product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 605™ anti-human CD8
catalog :
344741
quantity :
25 tests
price :
201 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV605
clone name :
SK1
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 15
Reference
Lah S, Kim S, Kang I, Kim H, Hupperetz C, Jung H, et al. Engineering second-generation TCR-T cells by site-specific integration of TRAF-binding motifs into the CD247 locus. J Immunother Cancer. 2023;11: pubmed publisher
Zhu X, Li Q, George V, Spanoudis C, Gilkes C, Shrestha N, et al. A novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice. Front Immunol. 2023;14:1114802 pubmed publisher
Estep B, Kuhlmann C, Osuka S, Suryavanshi G, Nagaoka Kamata Y, Samuel C, et al. Skewed fate and hematopoiesis of CD34+ HSPCs in umbilical cord blood amid the COVID-19 pandemic. iScience. 2022;25:105544 pubmed publisher
VanDyke D, Iglesias M, Tomala J, Young A, Smith J, Perry J, et al. Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection. Cell Rep. 2022;41:111478 pubmed publisher
Reuschl A, Mesner D, Shivkumar M, Whelan M, Pallett L, Guerra Assun xe7 xe3 o J, et al. HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells. Cell Rep. 2022;39:110650 pubmed publisher
Yen M, Ren J, Liu Q, Glassman C, Sheahan T, Picton L, et al. Facile discovery of surrogate cytokine agonists. Cell. 2022;185:1414-1430.e19 pubmed publisher
Leclercq G, Haegel H, Toso A, Zimmermann T, Green L, Steinhoff N, et al. JAK and mTOR inhibitors prevent cytokine release while retaining T cell bispecific antibody in vivo efficacy. J Immunother Cancer. 2022;10: pubmed publisher
Sulejmani O, Grunewald L, Andersch L, Schwiebert S, Klaus A, Winkler A, et al. Inhibiting Lysine Demethylase 1A Improves L1CAM-Specific CAR T Cell Therapy by Unleashing Antigen-Independent Killing via the FAS-FASL Axis. Cancers (Basel). 2021;13: pubmed publisher
Leclercq G, Haegel H, Schneider A, Giusti A, Marrer Berger E, Boetsch C, et al. Src/lck inhibitor dasatinib reversibly switches off cytokine release and T cell cytotoxicity following stimulation with T cell bispecific antibodies. J Immunother Cancer. 2021;9: pubmed publisher
Zirngibl F, Ivasko S, Grunewald L, Klaus A, Schwiebert S, Ruf P, et al. GD2-directed bispecific trifunctional antibody outperforms dinutuximab beta in a murine model for aggressive metastasized neuroblastoma. J Immunother Cancer. 2021;9: pubmed publisher
Xie G, Luo X, Ma T, Frouard J, Neidleman J, Hoh R, et al. Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4+ T cell subsets in vivo. Cell Rep. 2021;35:109038 pubmed publisher
Hsiue E, Wright K, Douglass J, Hwang M, Mog B, Pearlman A, et al. Targeting a neoantigen derived from a common TP53 mutation. Science. 2021;371: pubmed publisher
Glassman C, Mathiharan Y, Jude K, Su L, Panova O, Lupardus P, et al. Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells. Cell. 2021;184:983-999.e24 pubmed publisher
Peng S, Zaretsky J, Ng A, Chour W, Bethune M, Choi J, et al. Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood. Cell Rep. 2019;28:2728-2738.e7 pubmed publisher
Ling Y, Krishnan S, Chan C, Diep H, Ferens D, Chin Dusting J, et al. Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension. Pharmacol Res. 2017;116:77-86 pubmed publisher
product information
Antigen :
CD8
Apps. Abbrev. :
FC
Cat # :
344741
Clone :
SK1
Item :
Brilliant Violet 605™ anti-human CD8
Isotype :
Mouse IgG1, κ
Other Names :
T8, Leu2
Size :
25 tests
Price (USD) :
201 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV605
Application Notes :
Clone SK1 recognizes the a chain of CD8. Additional reported applications (for the relevant formats) include: proteogenomics^8, immunohistochemistry of acetone-fixed frozen tissue sections, and spatial biology (IBEX)^9,10. This clone was tested in-house and does not demonstrate utility for formalin-fixed paraffin-embedded (FFPE) human tonsil sections.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA