product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-human CD8
catalog :
344712
quantity :
100 tests
price :
325 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE/Cy7
clone name :
SK1
reactivity :
human, mouse, rhesus macaque
application :
flow cytometry
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 2b
Trapecar M, Khan S, Cohn B, Wu F, Sanjabi S. B cells are the predominant mediators of early systemic viral dissemination during rectal LCMV infection. Mucosal Immunol. 2018;11:1158-1167 pubmed publisher
  • flow cytometry; human; 1:50; loading ...; fig 2a
Siegers G, Barreira C, Postovit L, Dekaban G. CD11d ?2 integrin expression on human NK, B, and ?? T cells. J Leukoc Biol. 2017;101:1029-1035 pubmed publisher
  • flow cytometry; human
Jiang B, Wu X, Li X, Yang X, Zhou Y, Yan H, et al. Expansion of NK cells by engineered K562 cells co-expressing 4-1BBL and mMICA, combined with soluble IL-21. Cell Immunol. 2014;290:10-20 pubmed publisher
Chen Y, Tong P, WHITEMAN N, Moghaddam A, Zarghami M, Zuiani A, et al. Immune recall improves antibody durability and breadth to SARS-CoV-2 variants. Sci Immunol. 2022;:eabp8328 pubmed publisher
Mo Y, To K, Zhou R, Liu L, Cao T, Huang H, et al. Mitochondrial Dysfunction Associates With Acute T Lymphocytopenia and Impaired Functionality in COVID-19 Patients. Front Immunol. 2021;12:799896 pubmed publisher
Beatson R, Parente Pereira A, Halim L, Cozzetto D, Hull C, Whilding L, et al. TGF-β1 potentiates Vγ9Vδ2 T cell adoptive immunotherapy of cancer. Cell Rep Med. 2021;2:100473 pubmed publisher
Muliaditan T, Halim L, Whilding L, Draper B, Achkova D, Kausar F, et al. Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors. Cell Rep Med. 2021;2:100457 pubmed publisher
Gussarow D, Bonifacius A, Cossmann A, Stankov M, Mausberg P, Tischer Zimmermann S, et al. Long-Lasting Immunity Against SARS-CoV-2: Dream or Reality?. Front Med (Lausanne). 2021;8:770381 pubmed publisher
Bonifacius A, Tischer Zimmermann S, Dragon A, Gussarow D, Vogel A, Krettek U, et al. COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses. Immunity. 2021;54:340-354.e6 pubmed publisher
Pierce C, Preston Hurlburt P, Dai Y, Aschner C, Cheshenko N, Galen B, et al. Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients. Sci Transl Med. 2020;12: pubmed publisher
Lickliter J, Gan H, Voskoboynik M, Arulananda S, Gao B, Nagrial A, et al. A First-in-Human Dose Finding Study of Camrelizumab in Patients with Advanced or Metastatic Cancer in Australia. Drug Des Devel Ther. 2020;14:1177-1189 pubmed publisher
Arif S, Gomez Tourino I, Kamra Y, Pujol Autonell I, Hanton E, Tree T, et al. GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells. Diabetologia. 2020;63:1186-1198 pubmed publisher
Manukyan G, Martirosyan A, Slavik L, Margaryan S, Ulehlova J, Mikulkova Z, et al. Anti-domain 1 β2 glycoprotein antibodies increase expression of tissue factor on monocytes and activate NK Cells and CD8+ cells in vitro. Auto Immun Highlights. 2020;11:5 pubmed publisher
James K, Gomes T, Elmentaite R, Kumar N, Gulliver E, King H, et al. Distinct microbial and immune niches of the human colon. Nat Immunol. 2020;21:343-353 pubmed publisher
van Beek J, Flórez Grau G, Gorris M, Mathan T, Schreibelt G, Bol K, et al. Human pDCs Are Superior to cDC2s in Attracting Cytolytic Lymphocytes in Melanoma Patients Receiving DC Vaccination. Cell Rep. 2020;30:1027-1038.e4 pubmed publisher
Renner K, Bruss C, Schnell A, Koehl G, Becker H, Fante M, et al. Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy. Cell Rep. 2019;29:135-150.e9 pubmed publisher
Franco L, Gadkari M, Howe K, Sun J, Kardava L, Kumar P, et al. Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses. J Exp Med. 2019;216:384-406 pubmed publisher
Neal J, Li X, Zhu J, Giangarrà V, Grzeskowiak C, Ju J, et al. Organoid Modeling of the Tumor Immune Microenvironment. Cell. 2018;175:1972-1988.e16 pubmed publisher
Buchan S, Dou L, Remer M, Booth S, Dunn S, Lai C, et al. Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function. Immunity. 2018;49:958-970.e7 pubmed publisher
Iannetta M, Zingaropoli M, Bellizzi A, Morreale M, Pontecorvo S, D Abramo A, et al. Natalizumab Affects T-Cell Phenotype in Multiple Sclerosis: Implications for JCV Reactivation. PLoS ONE. 2016;11:e0160277 pubmed publisher
Lima J, Martins C, Nunes G, Sousa M, Branco J, Borrego L. Impact of Labor on Peripheral Blood Maternal T-Cell Subsets and on Regulatory T and B Cells. Reprod Sci. 2017;24:276-284 pubmed publisher
Ch en I, Tsau J, Molkentin J, Komatsu M, Hedrick S. Mechanisms of necroptosis in T cells. J Exp Med. 2011;208:633-41 pubmed publisher
product information
Antigen :
CD8
Apps. Abbrev. :
Flow Cytometry
Cat # :
344712
Clone :
SK1
Item :
PE/Cyanine7 anti-human CD8
Isotype :
Mouse IgG1, κ
Other Names :
T8, Leu2
Size :
100 tests
Price (USD) :
325 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE_CYANINE7
Application Notes :
Clone SK1 recognizes the a chain of CD8. Additional reported applications (for the relevant formats) include: proteogenomics 8 , immunohistochemistry of acetone-fixed frozen tissue sections, and spatial biology (IBEX) 9,10 . This clone was tested in-house and does not demonstrate utility for formalin-fixed paraffin-embedded (FFPE) human tonsil sections.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA