product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD272 (BTLA)
catalog :
344509
quantity :
25 tests
price :
143 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
MIH26
reactivity :
human
application :
flow cytometry
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 5c
Piancone F, Saresella M, Marventano I, La Rosa F, Zoppis M, Agostini S, et al. B Lymphocytes in Multiple Sclerosis: Bregs and BTLA/CD272 Expressing-CD19+ Lymphocytes Modulate Disease Severity. Sci Rep. 2016;6:29699 pubmed publisher
Bourdely P, Anselmi G, Vaivode K, Ramos R, Missolo Koussou Y, Hidalgo S, et al. Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells. Immunity. 2020;53:335-352.e8 pubmed publisher
Zhang J, Lu Y, Wang W, Liu G, Chen C, Shen L, et al. BTLA-Expressing Dendritic Cells in Patients With Tuberculosis Exhibit Reduced Production of IL-12/IFN-α and Increased Production of IL-4 and TGF-β, Favoring Th2 and Foxp3+ Treg Polarization. Front Immunol. 2020;11:518 pubmed publisher
Li X, Wang R, Fan P, Yao X, Qin L, Peng Y, et al. A Comprehensive Analysis of Key Immune Checkpoint Receptors on Tumor-Infiltrating T Cells From Multiple Types of Cancer. Front Oncol. 2019;9:1066 pubmed publisher
Abd Hamid M, Wang R, Yao X, Fan P, Li X, Chang X, et al. Enriched HLA-E and CD94/NKG2A interaction limits antitumor CD8+ tumor-infiltrating T lymphocyte responses. Cancer Immunol Res. 2019;: pubmed publisher
Anzengruber F, Ignatova D, Schlaepfer T, Chang Y, French L, Pascolo S, et al. Divergent LAG-3 versus BTLA, TIGIT, and FCRL3 expression in Sézary syndrome. Leuk Lymphoma. 2019;60:1899-1907 pubmed publisher
Spodzieja M, Lach S, Iwaszkiewicz J, Cesson V, Kalejta K, Olive D, et al. Design of short peptides to block BTLA/HVEM interactions for promoting anticancer T-cell responses. PLoS ONE. 2017;12:e0179201 pubmed publisher
product information
Antigen :
CD272
Apps. Abbrev. :
Flow Cytometry
Cat # :
344509
Clone :
MIH26
Item :
APC anti-human CD272 (BTLA)
Isotype :
Mouse IgG2a, κ
Other Names :
BTLA, B and T lymphocyte attenuator
Size :
25 tests
Price (USD) :
143 USD
Reactivity :
Human, African Green
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Immunogen :
Human BTLA transfected cells
Application Notes :
Additional reported applications (for the relevant formats) include: inhibition of T cell proliferation and cytokine production 1 . Clone MIH26 has agonistic activity on BTLA, resulting in the inhibition of activation. The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for use in in vitro and in vivo biofunctional assays.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA