LEAF™ Purified anti-human CD272 (BTLA) | BioLegend 344503 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

LEAF™ Purified anti-human CD272 (BTLA)

catalog :

344503

quantity :

50 μg

price :

150 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MIH26

reactivity :

human

application :

flow cytometry

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 3d	Domae E, Hirai Y, Ikeo T, Goda S, Shimizu Y. Cytokine-mediated activation of human ex vivo-expanded V?9V?2 T cells. Oncotarget. 2017;8:45928-45942 pubmed publisher
flow cytometry; human; loading ...; fig 3b	Kinosada H, Yasunaga J, Shimura K, Miyazato P, Onishi C, Iyoda T, et al. HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors. PLoS Pathog. 2017;13:e1006120 pubmed publisher
flow cytometry; human; loading ...; fig 5c	Piancone F, Saresella M, Marventano I, La Rosa F, Zoppis M, Agostini S, et al. B Lymphocytes in Multiple Sclerosis: Bregs and BTLA/CD272 Expressing-CD19+ Lymphocytes Modulate Disease Severity. Sci Rep. 2016;6:29699 pubmed publisher
flow cytometry; human; fig 7	Jutz S, Leitner J, Schmetterer K, Doel Perez I, Majdic O, Grabmeier Pfistershammer K, et al. Assessment of costimulation and coinhibition in a triple parameter T cell reporter line: Simultaneous measurement of NF-ÎºB, NFAT and AP-1. J Immunol Methods. 2016;430:10-20 pubmed publisher
	Celis Gutierrez J, Blattmann P, Zhai Y, Jarmuzynski N, Ruminski K, Gregoire C, et al. Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy. Cell Rep. 2019;27:3315-3330.e7 pubmed publisher
	Ripamonti A, Provasi E, Lorenzo M, De Simone M, Ranzani V, Vangelisti S, et al. Repression of miR-31 by BCL6 stabilizes the helper function of human follicular helper T cells. Proc Natl Acad Sci U S A. 2017;114:12797-12802 pubmed publisher

product information

Antigen :

CD272

Apps. Abbrev. :

Flow Cytometry, Agonist

Cat # :

344503

Clone :

MIH26

Item :

LEAF™ Purified anti-human CD272 (BTLA)

Isotype :

Mouse IgG2a, κ

Other Names :

BTLA, B and T lymphocyte attenuator

Size :

50 μg

Price (USD) :

150 USD

Reactivity :

Human, African Green

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

LEAF

Immunogen :

Human BTLA transfected cells

Application Notes :

Additional reported applications (for the relevant formats) include: inhibition of T cell proliferation and cytokine production 1 . Clone MIH26 has agonistic activity on BTLA, resulting in the inhibition of activation. The Ultra-LEAF™ purified antibody (Endotoxin 0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for use in in vitro and in vivo biofunctional assays.