product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human CD88 (C5aR)
catalog :
344302
quantity :
100 μg
price :
121 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S5/1
reactivity :
human
application :
flow cytometry, blocking or activating experiments
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1e
Kim J, Jeong J, Jung J, Jeon H, Lee S, Lim J, et al. Immunological characteristics and possible pathogenic role of urinary CD11c+ macrophages in lupus nephritis. Rheumatology (Oxford). 2020;: pubmed publisher
  • flow cytometry; human; fig 3a
Jeong J, Hong S, Kwon O, Ghang B, Hwang I, Kim Y, et al. CD14+ Cells with the Phenotype of Infiltrated Monocytes Consist of Distinct Populations Characterized by Anti-inflammatory as well as Pro-inflammatory Activity in Gouty Arthritis. Front Immunol. 2017;8:1260 pubmed publisher
  • flow cytometry; human; fig 4b
Janesch P, Rouha H, Weber S, Malafa S, Gross K, Maierhofer B, et al. Selective sensitization of human neutrophils to LukGH mediated cytotoxicity by Staphylococcus aureus and IL-8. J Infect. 2017;74:473-483 pubmed publisher
  • blocking or activating experiments; human; loading ...; fig 1a
An L, Gorman J, Stephens G, Swerdlow B, Warrener P, Bonnell J, et al. Complement C5a induces PD-L1 expression and acts in synergy with LPS through Erk1/2 and JNK signaling pathways. Sci Rep. 2016;6:33346 pubmed publisher
  • flow cytometry; human; fig 3
Hünniger K, Bieber K, Martin R, Lehnert T, Figge M, Löffler J, et al. A second stimulus required for enhanced antifungal activity of human neutrophils in blood is provided by anaphylatoxin C5a. J Immunol. 2015;194:1199-210 pubmed publisher
Cytlak U, Resteu A, Pagan S, Green K, Milne P, Maisuria S, et al. Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans. Immunity. 2020;53:353-370.e8 pubmed publisher
Friebel E, Kapolou K, Unger S, Núñez N, Utz S, Rushing E, et al. Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes. Cell. 2020;181:1626-1642.e20 pubmed publisher
Dutertre C, Becht E, Irac S, Khalilnezhad A, Narang V, Khalilnezhad S, et al. Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells. Immunity. 2019;51:573-589.e8 pubmed publisher
Evrard M, Kwok I, Chong S, Teng K, Becht E, Chen J, et al. Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions. Immunity. 2018;48:364-379.e8 pubmed publisher
Lee E, Gillrie M, Li L, Arnason J, Kim J, Babes L, et al. Leukotriene B4-Mediated Neutrophil Recruitment Causes Pulmonary Capillaritis during Lethal Fungal Sepsis. Cell Host Microbe. 2018;23:121-133.e4 pubmed publisher
Colley C, Popovic B, Sridharan S, Debreczeni J, Hargeaves D, Fung M, et al. Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors. MAbs. 2018;10:104-117 pubmed publisher
product information
Antigen :
CD88
Apps. Abbrev. :
Flow Cytometry
Cat # :
344302
Clone :
S5/1
Item :
Purified anti-human CD88 (C5aR)
Isotype :
Mouse IgG2a, κ
Other Names :
C5a ligand, C5a anaphylatoxin receptor, C5AR, C5R1, C5AR1
Size :
100 μg
Price (USD) :
121 USD
Reactivity :
Human, African Green, Baboon
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
Recombinant peptide huC5aR N-terminal -NT (Asp15-Asp27)
Application Notes :
Clone S5/1 blocks the binding of C5a to CD88.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA