product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human CD73 (Ecto-5'-nucleotidase)
catalog :
344003
quantity :
25 tests
price :
129 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
AD2
reactivity :
human
application :
flow cytometry
more info or order :
citations: 51
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1b
Marozin S, Simon Nobbe B, Irausek S, Chung L, Lepperdinger G. Kinship of conditionally immortalized cells derived from fetal bone to human bone-derived mesenchymal stroma cells. Sci Rep. 2021;11:10933 pubmed publisher
  • flow cytometry; human; fig 3
Rissiek A, Baumann I, Cuapio A, Mautner A, Kolster M, Arck P, et al. The expression of CD39 on regulatory T cells is genetically driven and further upregulated at sites of inflammation. J Autoimmun. 2015;58:12-20 pubmed publisher
  • flow cytometry; human
Schuler P, Saze Z, Hong C, Muller L, Gillespie D, Cheng D, et al. Human CD4+ CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells. Clin Exp Immunol. 2014;177:531-43 pubmed publisher
Ishiuchi N, Nakashima A, Maeda S, Miura Y, Miyasako K, Sasaki K, et al. Comparison of therapeutic effects of mesenchymal stem cells derived from superficial and deep subcutaneous adipose tissues. Stem Cell Res Ther. 2023;14:121 pubmed publisher
Robb K, Audet J, Gandhi R, Viswanathan S. Putative critical quality attribute matrix identifies mesenchymal stromal cells with potent immunomodulatory and angiogenic "fitness" ranges in response to culture process parameters. Front Immunol. 2022;13:972095 pubmed publisher
Liu C, Yu J, Liu B, Liu M, Song G, Zhu L, et al. BACH1 regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells. BMC Oral Health. 2022;22:536 pubmed publisher
Zhang J, Qu X, Li J, Harada A, Hua Y, Yoshida N, et al. Tissue Sheet Engineered Using Human Umbilical Cord-Derived Mesenchymal Stem Cells Improves Diabetic Wound Healing. Int J Mol Sci. 2022;23: pubmed publisher
Wang W, Yan M, Aarabi G, Peters U, Freytag M, Gosau M, et al. Cultivation of Cryopreserved Human Dental Pulp Stem Cells-A New Approach to Maintaining Dental Pulp Tissue. Int J Mol Sci. 2022;23: pubmed publisher
Hasmim M, Xiao M, Van Moer K, Kumar A, Oniga A, Mittelbronn M, et al. SNAI1-dependent upregulation of CD73 increases extracellular adenosine release to mediate immune suppression in TNBC. Front Immunol. 2022;13:982821 pubmed publisher
Dong N, Zhou P, Li D, Zhu H, Liu L, Ma H, et al. Intratracheal administration of umbilical cord-derived mesenchymal stem cells attenuates hyperoxia-induced multi-organ injury via heme oxygenase-1 and JAK/STAT pathways. World J Stem Cells. 2022;14:556-576 pubmed publisher
Yoshida R, Saigi M, Tani T, Springer B, Shibata H, Kitajima S, et al. MET-Induced CD73 Restrains STING-Mediated Immunogenicity of EGFR-Mutant Lung Cancer. Cancer Res. 2022;82:4079-4092 pubmed publisher
Liu C, Lu Y, Du P, Yang F, Guo P, Tang X, et al. Mesenchymal stem cells pretreated with proinflammatory cytokines accelerate skin wound healing by promoting macrophages migration and M2 polarization. Regen Ther. 2022;21:192-200 pubmed publisher
Polisetti N, Sharaf L, Reinhard T, Schlunck G. Isolation and ex vivo Expansion of Limbal Mesenchymal Stromal Cells. Bio Protoc. 2022;12: pubmed publisher
Chijimatsu R, Takeda T, Tsuji S, Sasaki K, Kato K, Kojima R, et al. Development of hydroxyapatite-coated nonwovens for efficient isolation of somatic stem cells from adipose tissues. Regen Ther. 2022;21:52-61 pubmed publisher
Zhu H, Zhuang Y, Li D, Dong N, Ma H, Liu L, et al. Cryo-Temperature Pretreatment Increases the Pro-Angiogenic Capacity of Three-Dimensional Mesenchymal Stem Cells via the PI3K-AKT Pathway. Cell Transplant. 2022;31:9636897221106996 pubmed publisher
Gao G, Wang L, Li C. Circ_0006790 carried by bone marrow mesenchymal stem cell-derived exosomes regulates S100A11 DNA methylation through binding to CBX7 in pancreatic ductal adenocarcinoma. Am J Cancer Res. 2022;12:1934-1959 pubmed
Sonoda S, Yamaza H, Yoshimaru K, Taguchi T, Yamaza T. Protocol to generate xenogeneic-free/serum-free human dental pulp stem cells. STAR Protoc. 2022;3:101386 pubmed publisher
Yao X, Ma Y, Zhou W, Liao Y, Jiang Z, Lin J, et al. In-cytoplasm mitochondrial transplantation for mesenchymal stem cells engineering and tissue regeneration. Bioeng Transl Med. 2022;7:e10250 pubmed publisher
Vaka R, Khan S, Ye B, Risha Y, Parent S, Courtman D, et al. Direct comparison of different therapeutic cell types susceptibility to inflammatory cytokines associated with COVID-19 acute lung injury. Stem Cell Res Ther. 2022;13:20 pubmed publisher
Sung S, Seo M, Kang K, Choi J, Lee S, Lim J, et al. Isolation and Characterization of Extracellular Vesicle from Mesenchymal Stem Cells of the Epidural Fat of the Spine. Asian Spine J. 2022;16:153-161 pubmed publisher
de Sousa B, Correia C, Ferreira J, Mano J, Furlani E, Soares dos Santos M, et al. Capacitive interdigitated system of high osteoinductive/conductive performance for personalized acting-sensing implants. NPJ Regen Med. 2021;6:80 pubmed publisher
Labedz Maslowska A, Szkaradek A, Mierzwinski T, Madeja Z, Zuba Surma E. Processing and Ex Vivo Expansion of Adipose Tissue-Derived Mesenchymal Stem/Stromal Cells for the Development of an Advanced Therapy Medicinal Product for use in Humans. Cells. 2021;10: pubmed publisher
Sung S, Kang K, Choi J, Lee S, Kim K, Lim J, et al. Comparisons of Extracellular Vesicles from Human Epidural Fat-Derived Mesenchymal Stem Cells and Fibroblast Cells. Int J Mol Sci. 2021;22: pubmed publisher
Cantoni C, Serra M, Parisi E, Azzarone B, Sementa A, Nasto L, et al. Stromal-like Wilms tumor cells induce human Natural Killer cell degranulation and display immunomodulatory properties towards NK cells. Oncoimmunology. 2021;10:1879530 pubmed publisher
Shi L, Han Q, Hong Y, Li W, Gong G, Cui J, et al. Inhibition of miR-199a-5p rejuvenates aged mesenchymal stem cells derived from patients with idiopathic pulmonary fibrosis and improves their therapeutic efficacy in experimental pulmonary fibrosis. Stem Cell Res Ther. 2021;12:147 pubmed publisher
Kenswil K, Pisterzi P, Sanchez Duffhues G, van Dijk C, Lolli A, Knuth C, et al. Endothelium-derived stromal cells contribute to hematopoietic bone marrow niche formation. Cell Stem Cell. 2021;28:653-670.e11 pubmed publisher
Costa M, Serra J, McDevitt T, Cabral J, da Silva C, Ferreira F. Dimethyloxalylglycine, a small molecule, synergistically increases the homing and angiogenic properties of human mesenchymal stromal cells when cultured as 3D spheroids. Biotechnol J. 2021;16:e2000389 pubmed publisher
Xin Y, Xu P, Wang X, Chen Y, Zhang Z, Zhang Y. Human foreskin-derived dermal stem/progenitor cell-conditioned medium combined with hyaluronic acid promotes extracellular matrix regeneration in diabetic wounds. Stem Cell Res Ther. 2021;12:49 pubmed publisher
Okamura G, Ebina K, Hirao M, Chijimatsu R, Yonetani Y, Etani Y, et al. Promoting Effect of Basic Fibroblast Growth Factor in Synovial Mesenchymal Stem Cell-Based Cartilage Regeneration. Int J Mol Sci. 2020;22: pubmed publisher
Labedz Maslowska A, Bryniarska N, Kubiak A, Kaczmarzyk T, Sekula Stryjewska M, Noga S, et al. Multilineage Differentiation Potential of Human Dental Pulp Stem Cells-Impact of 3D and Hypoxic Environment on Osteogenesis In Vitro. Int J Mol Sci. 2020;21: pubmed publisher
Lee E, Kim Y, Lim H, Ki G, Seo Y. The Histone Deacetylase Inhibitor (MS-275) Promotes Differentiation of Human Dental Pulp Stem Cells into Odontoblast-Like Cells Independent of the MAPK Signaling System. Int J Mol Sci. 2020;21: pubmed publisher
Peng H, Xue R, Ju Z, Qiu J, Wang J, Yan W, et al. Cancer-associated fibroblasts enhance the chemoresistance of CD73+ hepatocellular carcinoma cancer cells via HGF-Met-ERK1/2 pathway. Ann Transl Med. 2020;8:856 pubmed publisher
Schultheiß C, Paschold L, Simnica D, Mohme M, Willscher E, von Wenserski L, et al. Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease. Immunity. 2020;53:442-455.e4 pubmed publisher
Kicova M, Michalová Z, Coma M, Gabzdilova J, Dedinská K, Guman T, et al. The expression of CD73 on pathological B-cells is associated with shorter overall survival of patients with CLL. Neoplasma. 2020;67:933-938 pubmed publisher
Hong Y, He H, Jiang G, Zhang H, Tao W, Ding Y, et al. miR-155-5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction. Aging Cell. 2020;19:e13128 pubmed publisher
Bi R, Yin Q, Mei J, Chen K, Luo X, Fan Y, et al. Identification of human temporomandibular joint fibrocartilage stem cells with distinct chondrogenic capacity. Osteoarthritis Cartilage. 2020;28:842-852 pubmed publisher
Stocco E, Barbon S, Piccione M, Belluzzi E, Petrelli L, Pozzuoli A, et al. Infrapatellar Fat Pad Stem Cells Responsiveness to Microenvironment in Osteoarthritis: From Morphology to Function. Front Cell Dev Biol. 2019;7:323 pubmed publisher
Huang X, Zhang H, Liang X, Hong Y, Mao M, Han Q, et al. Adipose-Derived Mesenchymal Stem Cells Isolated from Patients with Abdominal Aortic Aneurysm Exhibit Senescence Phenomena. Oxid Med Cell Longev. 2019;2019:1305049 pubmed publisher
Zhang Y, Zhu W, He H, Fan B, Deng R, Hong Y, et al. Macrophage migration inhibitory factor rejuvenates aged human mesenchymal stem cells and improves myocardial repair. Aging (Albany NY). 2019;11:12641-12660 pubmed publisher
Ross N, Lohmann F, Carbonneau S, Fazal A, Weihofen W, Gleim S, et al. CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma. Nat Chem Biol. 2020;16:50-59 pubmed publisher
Sun T, Ju M, Dai X, Dong H, Gu W, Gao Y, et al. Multilevel defects in the hematopoietic niche in essential thrombocythemia. Haematologica. 2020;105:661-673 pubmed publisher
Kolodziej M, Strauss S, Lazaridis A, Bucan V, Kuhbier J, Vogt P, et al. Influence of glucose and insulin in human adipogenic differentiation models with adipose-derived stem cells. Adipocyte. 2019;8:254-264 pubmed publisher
Ryzhov S, May T, Dziodzio J, Emery I, Lucas F, Leclerc A, et al. Number of Circulating CD 73-Expressing Lymphocytes Correlates With Survival After Cardiac Arrest. J Am Heart Assoc. 2019;8:e010874 pubmed publisher
He H, Yu B, Liu Z, Ye G, You W, Hong Y, et al. Vascular progenitor cell senescence in patients with Marfan syndrome. J Cell Mol Med. 2019;23:4139-4152 pubmed publisher
Ali S, Turner J, Fountain S. P2Y2 and P2Y6 receptor activation elicits intracellular calcium responses in human adipose-derived mesenchymal stromal cells. Purinergic Signal. 2018;14:371-384 pubmed publisher
Wu L, Liu H, Guo H, Wu Q, Yu S, Qin Y, et al. Circulating and tumor-infiltrating myeloid-derived suppressor cells in cervical carcinoma patients. Oncol Lett. 2018;15:9507-9515 pubmed publisher
Jungwirth N, Salinas Tejedor L, Jin W, Gudi V, Skripuletz T, Stein V, et al. Mesenchymal Stem Cells Form 3D Clusters Following Intraventricular Transplantation. J Mol Neurosci. 2018;65:60-73 pubmed publisher
Blázquez Prunera A, Díez J, Gajardo R, Grancha S. Human mesenchymal stem cells maintain their phenotype, multipotentiality, and genetic stability when cultured using a defined xeno-free human plasma fraction. Stem Cell Res Ther. 2017;8:103 pubmed publisher
Saze Z, Schuler P, Hong C, Cheng D, Jackson E, Whiteside T. Adenosine production by human B cells and B cell-mediated suppression of activated T cells. Blood. 2013;122:9-18 pubmed publisher
Zhang M, Peng Y, Zhou Z, Zhou J, Wang Z, Lu M. Differentiation of human adipose-derived stem cells co-cultured with urothelium cell line toward a urothelium-like phenotype in a nude murine model. Urology. 2013;81:465.e15-22 pubmed publisher
Liao J, Al Shahrani M, Al Habib M, Tanaka T, Huang G. Cells isolated from inflamed periapical tissue express mesenchymal stem cell markers and are highly osteogenic. J Endod. 2011;37:1217-24 pubmed publisher
product information
Antigen :
CD73
Apps. Abbrev. :
FC
Cat # :
344003
Clone :
AD2
Item :
PE anti-human CD73 (Ecto-5'-nucleotidase)
Isotype :
Mouse IgG1, κ
Other Names :
Ecto-5'-nucleotidase, E.C3.1.3.5, L-VAP-2, NT5E, 5'-NT
Size :
25 tests
Price (USD) :
129 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Application Notes :
Additional reported applications (for the relevant formats) include:immunofluorescence^3.Clone AD2 has been noted to induce clustering and internalization of CD73 in vivo and inhibit metastasis in a murine breast cancer xenograft model^4.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA