product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-human HLA-A2
catalog :
343305
quantity :
25 tests
price :
129 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
BB7.2
reactivity :
human
application :
flow cytometry
more info or order :
citations: 24
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 3e, 3f
Albanese M, Tagawa T, Bouvet M, Maliqi L, Lutter D, Hoser J, et al. Epstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells. Proc Natl Acad Sci U S A. 2016;113:E6467-E6475 pubmed
  • flow cytometry; human; fig 5
Rancan C, Schirrmann L, Hüls C, Zeidler R, Moosmann A. Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells. PLoS Pathog. 2015;11:e1004906 pubmed publisher
  • flow cytometry; human
Matheson N, Peden A, Lehner P. Antibody-free magnetic cell sorting of genetically modified primary human CD4+ T cells by one-step streptavidin affinity purification. PLoS ONE. 2014;9:e111437 pubmed publisher
Xiao C, Ren Z, Zhang B, Mao L, Zhu G, Gao L, et al. Insufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults. Nat Aging. 2023;3:418-435 pubmed publisher
Jenkins E, K xf6 rbel M, O Brien Ball C, McColl J, Chen K, Kotowski M, et al. Antigen discrimination by T cells relies on size-constrained microvillar contact. Nat Commun. 2023;14:1611 pubmed publisher
Sun Y, Papadaki G, Devlin C, Danon J, Young M, Winters T, et al. Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes. Sci Adv. 2023;9:eade7151 pubmed publisher
Vidard L. 4-1BB and cytokines trigger human NK, γδ T, and CD8+ T cell proliferation and activation, but are not required for their effector functions. Immun Inflamm Dis. 2023;11:e749 pubmed publisher
Xiao C, Mao L, Wang Z, Gao L, Zhu G, Su J, et al. SARS-CoV-2 variant B.1.1.7 caused HLA-A2+ CD8+ T cell epitope mutations for impaired cellular immune response. iScience. 2022;25:103934 pubmed publisher
Qiu C, Xiao C, Wang Z, Zhu G, Mao L, Chen X, et al. CD8+ T-Cell Epitope Variations Suggest a Potential Antigen HLA-A2 Binding Deficiency for Spike Protein of SARS-CoV-2. Front Immunol. 2021;12:764949 pubmed publisher
Melacarne A, Ferrari V, Tiraboschi L, Mishto M, Liepe J, Aralla M, et al. Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides. Cell Rep. 2021;36:109312 pubmed publisher
Deng J, Pan J, Qiu M, Mao L, Wang Z, Zhu G, et al. Identification of HLA-A2 restricted CD8+ T cell epitopes in SARS-CoV-2 structural proteins. J Leukoc Biol. 2021;110:1171-1180 pubmed publisher
Pellegrini J, Martin C, Morelli M, Schander J, Tateosian N, Amiano N, et al. PGE2 displays immunosuppressive effects during human active tuberculosis. Sci Rep. 2021;11:13559 pubmed publisher
Pettmann J, Huhn A, Abu Shah E, Kutuzov M, Wilson D, Dustin M, et al. The discriminatory power of the T cell receptor. elife. 2021;10: pubmed publisher
FitzPatrick M, Provine N, Garner L, Powell K, Amini A, Irwin S, et al. Human intestinal tissue-resident memory T cells comprise transcriptionally and functionally distinct subsets. Cell Rep. 2021;34:108661 pubmed publisher
Bagati A, Kumar S, Jiang P, Pyrdol J, Zou A, Godicelj A, et al. Integrin αvβ6-TGFβ-SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer. Cancer Cell. 2021;39:54-67.e9 pubmed publisher
Klatt M, Aretz Z, Curcio M, Gejman R, Jones H, Scheinberg D. An input-controlled model system for identification of MHC bound peptides enabling laboratory comparisons of immunopeptidome experiments. J Proteomics. 2020;228:103921 pubmed publisher
Barili V, Fisicaro P, Montanini B, Acerbi G, Filippi A, Forleo G, et al. Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection. Nat Commun. 2020;11:604 pubmed publisher
Abdelaziz M, Ossmann S, Kaufmann A, Leitner J, Steinberger P, Willimsky G, et al. Development of a Human Cytomegalovirus (HCMV)-Based Therapeutic Cancer Vaccine Uncovers a Previously Unsuspected Viral Block of MHC Class I Antigen Presentation. Front Immunol. 2019;10:1776 pubmed publisher
Gu C, Wang L, Zurawski S, Oh S. Signaling Cascade through DC-ASGPR Induces Transcriptionally Active CREB for IL-10 Induction and Immune Regulation. J Immunol. 2019;: pubmed publisher
Gärtner K, Luckner M, Wanner G, Zeidler R. Engineering extracellular vesicles as novel treatment options: exploiting herpesviral immunity in CLL. J Extracell Vesicles. 2019;8:1573051 pubmed publisher
Lai J, Tan W, Too C, Choo J, Wong L, Mustafa F, et al. Targeting Epstein-Barr virus-transformed B lymphoblastoid cells using antibodies with T-cell receptor-like specificities. Blood. 2016;128:1396-407 pubmed publisher
Ameres S, Besold K, Plachter B, Moosmann A. CD8 T cell-evasive functions of human cytomegalovirus display pervasive MHC allele specificity, complementarity, and cooperativity. J Immunol. 2014;192:5894-905 pubmed publisher
Schuler P, Harasymczuk M, Visus C, DeLeo A, Trivedi S, Lei Y, et al. Phase I dendritic cell p53 peptide vaccine for head and neck cancer. Clin Cancer Res. 2014;20:2433-44 pubmed publisher
Wang X, Berger C, Wong C, Forman S, Riddell S, Jensen M. Engraftment of human central memory-derived effector CD8+ T cells in immunodeficient mice. Blood. 2011;117:1888-98 pubmed publisher
product information
Antigen :
HLA-A2
Apps. Abbrev. :
FC
Cat # :
343305
Clone :
BB7.2
Item :
PE anti-human HLA-A2
Isotype :
Mouse IgG2b, κ
Other Names :
MHC-class I
Size :
25 tests
Price (USD) :
129 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Immunogen :
Papain solubilized HLA-A2
Application Notes :
The BB7.2 antibody recognizes human leukocyte antigen (HLA) A2 which is a subset of MHC-class I molecules encoded by A*02 alleles.Additional reported applications (for the relevant formats) include: immunoprecipitation^3.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA