Purified anti-human C5L2 | BioLegend 342402 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human C5L2

catalog :

342402

quantity :

100 μg

price :

229 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1D9-M12

reactivity :

human

application :

western blot, flow cytometry, immunohistochemistry - paraffin section, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; fig 1f	Su S, Chen J, Yao H, Liu J, Yu S, Lao L, et al. CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness. Cell. 2018;172:841-856.e16 pubmed publisher
flow cytometry; human; fig 4b	Janesch P, Rouha H, Weber S, Malafa S, Gross K, Maierhofer B, et al. Selective sensitization of human neutrophils to LukGH mediated cytotoxicity by Staphylococcus aureus and IL-8. J Infect. 2017;74:473-483 pubmed publisher
blocking or activating experiments; human; loading ...; fig 1a	An L, Gorman J, Stephens G, Swerdlow B, Warrener P, Bonnell J, et al. Complement C5a induces PD-L1 expression and acts in synergy with LPS through Erk1/2 and JNK signaling pathways. Sci Rep. 2016;6:33346 pubmed publisher
	Yu S, Lu Y, Su A, Chen J, Li J, Zhou B, et al. A CD10-OGP Membrane Peptolytic Signaling Axis in Fibroblasts Regulates Lipid Metabolism of Cancer Stem Cells via SCD1. Adv Sci (Weinh). 2021;8:e2101848 pubmed publisher
	Fukushima T, Tanaka Y, Hamey F, Chang C, Oki T, Asada S, et al. Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium. Cell Rep. 2019;29:4144-4158.e7 pubmed publisher
	Kolter J, Feuerstein R, Zeis P, Hagemeyer N, Paterson N, d Errico P, et al. A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves. Immunity. 2019;50:1482-1497.e7 pubmed publisher
	Colley C, Popovic B, Sridharan S, Debreczeni J, Hargeaves D, Fung M, et al. Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors. MAbs. 2018;10:104-117 pubmed publisher
	Fonseca M, McGuire S, Counts S, Tenner A. Complement activation fragment C5a receptors, CD88 and C5L2, are associated with neurofibrillary pathology. J Neuroinflammation. 2013;10:25 pubmed publisher

product information

Antigen :

C5L2

Apps. Abbrev. :

Flow Cytometry, Western Blotting

Cat # :

342402

Clone :

1D9-M12

Item :

Purified anti-human C5L2

Isotype :

Mouse IgG2a, κ

Other Names :

GPR77, C5a receptor-like 2, C5a anaphylatoxin chemotactic receptor

Size :

100 μg

Price (USD) :

229 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Application Notes :

Additional reported applications include: Western blotting 1,3 and blocking 2,3 . The LEAF or Ultra-LEAF purified antibody is recommended for functional assays (contact our custom solutions team) . . Clone 1D9-M12 is known to block C5a binding to C5L2, but does not react with C5a receptor. It has been reported that this clone is not effective in immunohistochemistry of formalin-fixed paraffin-embedded sections 1 .

more info or order :

BioLegend product webpage