product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-human CD40
catalog :
334332
quantity :
100 tests
price :
402 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV421
clone name :
5C3
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 4
Reference
Kerdidani D, Aerakis E, Verrou K, Angelidis I, Douka K, Maniou M, et al. Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts. J Exp Med. 2022;219: pubmed publisher
Hu X, Zhang A, Pan W, Xin Q, Chen J, Zhang L, et al. An IgD-Fc-Ig fusion protein restrains the activation of T and B cells by inhibiting IgD-IgDR-Lck signaling in rheumatoid arthritis. Acta Pharmacol Sin. 2022;43:387-400 pubmed publisher
Takiguchi H, Yang C, Yang C, Sahin B, Whalen B, Milne S, et al. Macrophages with reduced expressions of classical M1 and M2 surface markers in human bronchoalveolar lavage fluid exhibit pro-inflammatory gene signatures. Sci Rep. 2021;11:8282 pubmed publisher
Zimmerman M, Quicke K, O Neal J, Arora N, Machiah D, Priyamvada L, et al. Cross-Reactive Dengue Virus Antibodies Augment Zika Virus Infection of Human Placental Macrophages. Cell Host Microbe. 2018;24:731-742.e6 pubmed publisher
product information
Antigen :
CD40
Apps. Abbrev. :
FC
Cat # :
334332
Clone :
5C3
Item :
Brilliant Violet 421™ anti-human CD40
Isotype :
Mouse IgG1, κ
Other Names :
BP50, TNFRSF5
Size :
100 tests
Price (USD) :
402 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV421
Application Notes :
Additional reported applications (for the relevant formats) include: costimulation of B cell proliferation^1, partial inhibition of CD40 binding to CD40L^3, and B cell rescue from apoptosis^1. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA