product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-human CD40
catalog :
334321
quantity :
25 tests
price :
141 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE/Cy7
clone name :
5C3
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 6h
Findlay E, Currie A, Zhang A, Ovciarikova J, Young L, Stevens H, et al. Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy. Oncoimmunology. 2019;8:1608106 pubmed publisher
Mehta A, Cheney E, Hartl C, Pantelidou C, Oliwa M, Castrillon J, et al. Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer. Nat Cancer. 2021;2:66-82 pubmed publisher
Nowak W, Grendas L, Sanmarco L, Estecho I, Arena Á, Eberhardt N, et al. Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR. EBioMedicine. 2019;50:290-305 pubmed publisher
Grandclaudon M, Perrot Dockès M, Trichot C, Karpf L, Abouzid O, Chauvin C, et al. A Quantitative Multivariate Model of Human Dendritic Cell-T Helper Cell Communication. Cell. 2019;179:432-447.e21 pubmed publisher
Ziebart A, Huber U, Jeske S, Laban S, Doescher J, Hoffmann T, et al. The influence of chemotherapy on adenosine-producing B cells in patients with head and neck squamous cell carcinoma. Oncotarget. 2018;9:5834-5847 pubmed publisher
Rusconi M, Gerardi F, Santus W, Lizio A, Sansone V, Lunetta C, et al. Inflammatory role of dendritic cells in Amyotrophic Lateral Sclerosis revealed by an analysis of patients' peripheral blood. Sci Rep. 2017;7:7853 pubmed publisher
product information
Antigen :
CD40
Apps. Abbrev. :
Flow Cytometry
Cat # :
334321
Clone :
5C3
Item :
PE/Cyanine7 anti-human CD40
Isotype :
Mouse IgG1, κ
Other Names :
BP50, TNFRSF5
Size :
25 tests
Price (USD) :
141 USD
Reactivity :
Human, Cynomolgus, Rhesus
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE_CYANINE7
Application Notes :
Additional reported applications (for the relevant formats) include: costimulation of B cell proliferation 1 , partial inhibition of CD40 binding to CD40L 3 , and B cell rescue from apoptosis 1 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA