product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD68
catalog :
333810
quantity :
100 tests
price :
320 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
Y1/82A
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig s5h
Qin L, Wang L, Zhang J, Zhou H, Yang Z, Wang Y, et al. Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancer. Sci Adv. 2022;8:eabn3774 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:20; loading ...; fig 1g
Patra V, Strobl J, Gruber Wackernagel A, Vieyra Garcia P, Stary G, Wolf P. CD11b+ cells markedly express the itch cytokine interleukin-31 in polymorphic light eruption. Br J Dermatol. 2019;181:1079-1081 pubmed publisher
  • flow cytometry; human; fig s3
Llibre A, López Macías C, Marafioti T, Mehta H, Partridge A, Kanzig C, et al. LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation. J Immunol. 2016;196:2085-94 pubmed publisher
  • immunohistochemistry; human; 1:10; fig 2
Xue J, Sharma V, Hsieh M, Chawla A, Murali R, Pandol S, et al. Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis. Nat Commun. 2015;6:7158 pubmed publisher
Chung J, Tang P, Chan M, Xue V, Huang X, Ng C, et al. Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma. Nat Commun. 2023;14:1794 pubmed publisher
Jia J, Zheng L, Ye L, Chen J, Shu S, Xu S, et al. CD11c+ microglia promote white matter repair after ischemic stroke. Cell Death Dis. 2023;14:156 pubmed publisher
Cao B, Liu M, Wang L, Zhu K, Cai M, Chen X, et al. Remodelling of tumour microenvironment by microwave ablation potentiates immunotherapy of AXL-specific CAR T cells against non-small cell lung cancer. Nat Commun. 2022;13:6203 pubmed publisher
Teng Y, Zou M, Liu S, Jia Y, Zhang K, Yuan Z, et al. Dual-Action Icariin-Containing Thermosensitive Hydrogel for Wound Macrophage Polarization and Hair-Follicle Neogenesis. Front Bioeng Biotechnol. 2022;10:902894 pubmed publisher
Liu W, xd6 stberg N, Yalcınkaya M, Dou H, Endo Umeda K, Tang Y, et al. Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis. J Clin Invest. 2022;132: pubmed publisher
Wu J, Feng Z, Chen L, Li Y, Bian H, Geng J, et al. TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models. Nat Commun. 2022;13:676 pubmed publisher
Sun L, Kees T, Almeida A, Liu B, He X, Ng D, et al. Activating a collaborative innate-adaptive immune response to control metastasis. Cancer Cell. 2021;39:1361-1374.e9 pubmed publisher
Chen Y, Yan B, Xu F, Hui Z, Zhao G, Liu J, et al. Neoadjuvant chemoimmunotherapy in resectable stage IIIA/IIIB non-small cell lung cancer. Transl Lung Cancer Res. 2021;10:2193-2204 pubmed publisher
Obradovic A, Chowdhury N, Haake S, Ager C, Wang V, Vlahos L, et al. Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages. Cell. 2021;184:2988-3005.e16 pubmed publisher
Luvanda M, Posch W, Vosper J, Zaderer V, Noureen A, Lass Fl xf6 rl C, et al. Dexamethasone Promotes Aspergillus fumigatus Growth in Macrophages by Triggering M2 Repolarization via Targeting PKM2. J Fungi (Basel). 2021;7: pubmed publisher
Tamo L, Fytianos K, Caldana F, Simillion C, Feki A, Nita I, et al. Interactome Analysis of iPSC Secretome and Its Effect on Macrophages In Vitro. Int J Mol Sci. 2021;22: pubmed publisher
Ma L, Gonzàlez Juncà A, Zheng Y, Ouyang H, Illa Bochaca I, Horst K, et al. Inflammation Mediates the Development of Aggressive Breast Cancer Following Radiotherapy. Clin Cancer Res. 2021;27:1778-1791 pubmed publisher
Rai M, Hammonds J, Pujato M, Mayhew C, Roskin K, Spearman P. Comparative analysis of human microglial models for studies of HIV replication and pathogenesis. Retrovirology. 2020;17:35 pubmed publisher
Walter F, Winter E, Rahn S, Heidland J, Meier S, Struzek A, et al. Chitosan nanoparticles as antigen vehicles to induce effective tumor specific T cell responses. PLoS ONE. 2020;15:e0239369 pubmed publisher
Thieme C, Anft M, Paniskaki K, Blazquez Navarro A, Doevelaar A, Seibert F, et al. Robust T Cell Response Toward Spike, Membrane, and Nucleocapsid SARS-CoV-2 Proteins Is Not Associated with Recovery in Critical COVID-19 Patients. Cell Rep Med. 2020;1:100092 pubmed publisher
Wang X, Luo X, Chen C, Tang Y, Li L, Mo B, et al. The Ap-2α/Elk-1 axis regulates Sirpα-dependent tumor phagocytosis by tumor-associated macrophages in colorectal cancer. Signal Transduct Target Ther. 2020;5:35 pubmed publisher
Hou X, Chen G, Bracamonte Baran W, Choi H, Diny N, Sung J, et al. The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis. Cell Rep. 2019;28:172-189.e7 pubmed publisher
Rahn S, Krüger S, Mennrich R, Goebel L, Wesch D, Oberg H, et al. POLE Score: a comprehensive profiling of programmed death 1 ligand 1 expression in pancreatic ductal adenocarcinoma. Oncotarget. 2019;10:1572-1588 pubmed publisher
Lin J, Izar B, Wang S, Yapp C, Mei S, Shah P, et al. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. elife. 2018;7: pubmed publisher
Xiang W, Shi R, Kang X, Zhang X, Chen P, Zhang L, et al. Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression. Nat Commun. 2018;9:2574 pubmed publisher
Du Q, Wu X, Wang T, Yang X, Wang Z, Niu Y, et al. Porcine Circovirus Type 2 Suppresses IL-12p40 Induction via Capsid/gC1qR-Mediated MicroRNAs and Signalings. J Immunol. 2018;201:533-547 pubmed publisher
Carlsen T, Kjærsgaard P, Jørgensen T, Foldbjerg R, Nielsen M, Poulsen T, et al. Interleukin-1α activation and localization in lipopolysaccharide-stimulated human monocytes and macrophages. J Immunol Methods. 2015;422:59-71 pubmed publisher
Bushway M, Gerber S, Fenton B, Miller R, Lord E, Murphy S. Morphological and phenotypic analyses of the human placenta using whole mount immunofluorescence. Biol Reprod. 2014;90:110 pubmed publisher
Ciccia F, Alessandro R, Rizzo A, Accardo Palumbo A, Raimondo S, Raiata F, et al. Macrophage phenotype in the subclinical gut inflammation of patients with ankylosing spondylitis. Rheumatology (Oxford). 2014;53:104-13 pubmed publisher
product information
Antigen :
CD68
Apps. Abbrev. :
ICFC
Cat # :
333810
Clone :
Y1/82A
Item :
APC anti-human CD68
Isotype :
Mouse IgG2b, κ
Other Names :
Macrosialin
Size :
100 tests
Price (USD) :
320 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Application Notes :
Additional reported application: immunohistochemical staining of frozen tissue sections. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA