Ultra-LEAF™ Purified anti-human CD335 (NKp46) | BioLegend 331947 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-human CD335 (NKp46)

catalog :

331947

quantity :

100 μg

price :

198 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9.00E+02

reactivity :

human, mouse

application :

flow cytometry, blocking or activating experiments, other, mass cytometry

more info or order :

BioLegend product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; loading ...; fig s5d	Jiang Z, Qin L, Tang Y, Liao R, Shi J, He B, et al. Human induced-T-to-natural killer cells have potent anti-tumour activities. Biomark Res. 2022;10:13 pubmed publisher
blocking or activating experiments; human; 10 ug/ml; loading ...; fig 2e	Zhu Y, Xie J, Shi J. Rac1/ROCK-driven membrane dynamics promote natural killer cell cytotoxicity via granzyme-induced necroptosis. BMC Biol. 2021;19:140 pubmed publisher
flow cytometry; human; loading ...; fig s1	Katano I, Ito R, Kawai K, Takahashi T. Improved Detection of in vivo Human NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity Using a Novel NOG-FcγR-Deficient Human IL-15 Transgenic Mouse. Front Immunol. 2020;11:532684 pubmed publisher
other; mouse	Tseng H, Xiong W, Badeti S, Yang Y, Ma M, Liu T, et al. Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma. Nat Commun. 2020;11:4810 pubmed publisher
flow cytometry; human; loading ...	Hood S, Cosma G, Foulds G, Johnson C, Reeder S, McArdle S, et al. Identifying prostate cancer and its clinical risk in asymptomatic men using machine learning of high dimensional peripheral blood flow cytometric natural killer cell subset phenotyping data. elife. 2020;9: pubmed publisher
mass cytometry; human; loading ...; fig 1b, 1d, s2	Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed publisher
flow cytometry; human; loading ...	Sanz Ortega L, Rojas J, Portilla Y, Pérez Yagüe S, Barber D. Magnetic Nanoparticles Attached to the NK Cell Surface for Tumor Targeting in Adoptive Transfer Therapies Does Not Affect Cellular Effector Functions. Front Immunol. 2019;10:2073 pubmed publisher
	van Vliet A, Peters E, Vodegel D, Steenmans D, Raimo M, Gibbs S, et al. Early TRAIL-engagement elicits potent multimodal targeting of melanoma by CD34+ progenitor cell-derived NK cells. iScience. 2023;26:107078 pubmed publisher
	Cluff E, Magdaleno C, Fernandez E, House T, Swaminathan S, Varadaraj A, et al. Hypoxia-inducible factor-1 alpha expression is induced by IL-2 via the PI3K/mTOR pathway in hypoxic NK cells and supports effector functions in NKL cells and ex vivo expanded NK cells. Cancer Immunol Immunother. 2022;: pubmed publisher
	Hudson W, Gensheimer J, Hashimoto M, Wieland A, Valanparambil R, Li P, et al. Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection. Immunity. 2019;51:1043-1058.e4 pubmed publisher

product information

Antigen :

CD335

Apps. Abbrev. :

FC, FA

Cat # :

331947

Clone :

9.00E+02

Item :

Ultra-LEAF™ Purified anti-human CD335 (NKp46)

Isotype :

Mouse IgG1, κ

Other Names :

NKp46, NCR1

Size :

100 μg

Price (USD) :

198 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ULEAF

Immunogen :

NKp46-Fc fusion protein

Application Notes :

Clone 9E2 has been shown to block NK activation through NKp46.^6;

more info or order :

BioLegend product webpage