Purified anti-human CD58 (LFA-3) | BioLegend 330902 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-human CD58 (LFA-3)

catalog :

330902

quantity :

100 μg

price :

118 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TS2/9

reactivity :

human

application :

immunoprecipitation, flow cytometry, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:50; loading ...; fig 1e	Zurli V, Montecchi T, Heilig R, Poschke I, Volkmar M, Wimmer G, et al. Phosphoproteomics of CD2 signaling reveals AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells. Sci Signal. 2020;13: pubmed publisher
blocking or activating experiments; human; loading ...; fig 1c	Rölle A, Halenius A, Ewen E, Cerwenka A, Hengel H, Momburg F. CD2-CD58 interactions are pivotal for the activation and function of adaptive natural killer cells in human cytomegalovirus infection. Eur J Immunol. 2016;46:2420-2425 pubmed publisher
flow cytometry; human; fig 1	Jutz S, Leitner J, Schmetterer K, Doel Perez I, Majdic O, Grabmeier Pfistershammer K, et al. Assessment of costimulation and coinhibition in a triple parameter T cell reporter line: Simultaneous measurement of NF-ÎºB, NFAT and AP-1. J Immunol Methods. 2016;430:10-20 pubmed publisher
	Li Y, Moriyama T, Yoshimura S, Zhao X, Li Z, Yang X, et al. PAX5 epigenetically orchestrates CD58 transcription and modulates blinatumomab response in acute lymphoblastic leukemia. Sci Adv. 2022;8:eadd6403 pubmed publisher
	Xiong Y, Motomura H, Tamori S, Ozaki A, Onaga C, Hara Y, et al. High Expression of CD58 and ALDH1A3 Predicts a Poor Prognosis in Basal-like Breast Cancer. Anticancer Res. 2022;42:5223-5232 pubmed publisher
	Grandclaudon M, Perrot Dockès M, Trichot C, Karpf L, Abouzid O, Chauvin C, et al. A Quantitative Multivariate Model of Human Dendritic Cell-T Helper Cell Communication. Cell. 2019;179:432-447.e21 pubmed publisher

product information

Antigen :

CD58

Apps. Abbrev. :

FC, IP

Cat # :

330902

Clone :

TS2/9

Item :

Purified anti-human CD58 (LFA-3)

Isotype :

Mouse IgG1, κ

Other Names :

Lymphocyte function-associated antigen 3, LFA-3

Size :

100 μg

Price (USD) :

118 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PURE

Immunogen :

Human cytolytic T cells

Application Notes :

Additional reported applications include: immunoprecipitation^1, inhibition of cytolytic activity^1, augment of IL-1 release by TE cells^2;

more info or order :

BioLegend product webpage