product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Pacific Blue™ anti-human CD279 (PD-1)
catalog :
329916
quantity :
100 μg
price :
323 USD
clonality :
monoclonal
host :
mouse
conjugate :
Pacific Blue
clone name :
EH12.2H7
reactivity :
human, rhesus macaque
application :
flow cytometry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2c
Lu E, Wolfreys F, Muppidi J, Xu Y, Cyster J. S-Geranylgeranyl-L-glutathione is a ligand for human B cell-confinement receptor P2RY8. Nature. 2019;: pubmed publisher
  • flow cytometry; rhesus macaque; loading ...; fig s11c
Byrareddy S, Arthos J, Cicala C, Villinger F, Ortiz K, Little D, et al. Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy. Science. 2016;354:197-202 pubmed
Wu W, Chen Y, Huang L, Li W, Tao C, Shen H. Point mutation screening of tumor neoantigens and peptide-induced specific cytotoxic T lymphocytes using The Cancer Genome Atlas database. Oncol Lett. 2020;20:123 pubmed publisher
Sun B, Yang D, Dai H, Liu X, Jia R, Cui X, et al. Eradication of Hepatocellular Carcinoma by NKG2D-Based CAR-T Cells. Cancer Immunol Res. 2019;7:1813-1823 pubmed publisher
Sampedro Nuñez M, Serrano Somavilla A, Adrados M, Cameselle Teijeiro J, Blanco Carrera C, Cabezas Agricola J, et al. Analysis of expression of the PD-1/PD-L1 immune checkpoint system and its prognostic impact in gastroenteropancreatic neuroendocrine tumors. Sci Rep. 2018;8:17812 pubmed publisher
Zhao Y, Harrison D, Song Y, Ji J, Huang J, Hui E. Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells. Cell Rep. 2018;24:379-390.e6 pubmed publisher
Subudhi S, Aparicio A, Gao J, Zurita A, Araujo J, Logothetis C, et al. Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities. Proc Natl Acad Sci U S A. 2016;113:11919-11924 pubmed
Conrad J, Ramalingam R, Smith R, Barnett L, Lorey S, Wei J, et al. Dominant clonotypes within HIV-specific T cell responses are programmed death-1high and CD127low and display reduced variant cross-reactivity. J Immunol. 2011;186:6871-85 pubmed publisher
Monteiro P, Gosselin A, Wacleche V, El Far M, Said E, Kared H, et al. Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin ?7. J Immunol. 2011;186:4618-30 pubmed publisher
Radziewicz H, Ibegbu C, Hon H, Bedard N, Bruneau J, Workowski K, et al. Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling. J Immunol. 2010;184:2410-22 pubmed publisher
Vojnov L, Reed J, Weisgrau K, Rakasz E, Loffredo J, Piaskowski S, et al. Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic. J Virol. 2010;84:753-64 pubmed publisher
Jones R, Yue F, Gu X, Hunter D, Mujib S, Gyenes G, et al. Human immunodeficiency virus type 1 escapes from interleukin-2-producing CD4+ T-cell responses without high-frequency fixation of mutations. J Virol. 2009;83:8722-32 pubmed publisher
Chang W, Kim J, Kim Y, Kim Y, Lee J, Azuma M, et al. Cutting edge: Programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy. J Immunol. 2008;181:6707-10 pubmed
Zahn R, Rett M, Korioth Schmitz B, Sun Y, Buzby A, Goldstein S, et al. Simian immunodeficiency virus (SIV)-specific CD8+ T-cell responses in vervet African green monkeys chronically infected with SIVagm. J Virol. 2008;82:11577-88 pubmed publisher
product information
Antigen :
CD279
Apps. Abbrev. :
Flow Cytometry
Cat # :
329916
Clone :
EH12.2H7
Item :
Pacific Blue™ anti-human CD279 (PD-1)
Isotype :
Mouse IgG1, κ
Other Names :
PD-1, PDCD1
Size :
100 μg
Price (USD) :
323 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PB
Application Notes :
Additional reported applications (for the relevant formats) include: blocking of ligand binding 1-3 , immunohistochemical staining of paraformaldehyde fixed frozen sections 13 , and spatial biology (IBEX) 15,16 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 329911 and 329912). For highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 329926) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA