product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-human CD107a (LAMP-1)
catalog :
328626
quantity :
100 tests
price :
396 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV421
clone name :
H4A3
reactivity :
human
application :
flow cytometry
more info or order :
citations: 13
Reference
Motozono C, Toyoda M, Zahradník J, Saito A, Nasser H, Tan T, et al. SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity. Cell Host Microbe. 2021;29:1124-1136.e11 pubmed publisher
Clayton K, Mylvaganam G, Villasmil Ocando A, Stuart H, Maus M, Rashidian M, et al. HIV-infected macrophages resist efficient NK cell-mediated killing while preserving inflammatory cytokine responses. Cell Host Microbe. 2021;29:435-447.e9 pubmed publisher
Sim M, Rajagopalan S, Altmann D, Boyton R, Sun P, Long E. Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Sagebiel A, Steinert F, Lunemann S, Korner C, Schreurs R, Altfeld M, et al. Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine. Nat Commun. 2019;10:975 pubmed publisher
Jackson E, Zhang C, Kiani Z, Lisovsky I, Tallon B, Del Corpo A, et al. HIV exposed seronegative (HESN) compared to HIV infected individuals have higher frequencies of telomeric Killer Immunoglobulin-like Receptor (KIR) B motifs; Contribution of KIR B motif encoded genes to NK cell responsiveness. PLoS ONE. 2017;12:e0185160 pubmed publisher
Dai H, Griffin N, Bolyard C, Mao H, Zhang J, Cripe T, et al. The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells. Immunity. 2017;47:159-170.e10 pubmed publisher
Korner C, Simoneau C, Schommers P, Granoff M, Ziegler M, Hölzemer A, et al. HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells. Cell Host Microbe. 2017;22:111-119.e4 pubmed publisher
Roberts E, Carnathan D, Li H, Shaw G, Silvestri G, Betts M. Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques. PLoS Pathog. 2016;12:e1006135 pubmed publisher
Chalan P, Bijzet J, Kroesen B, Boots A, Brouwer E. Altered Natural Killer Cell Subsets in Seropositive Arthralgia and Early Rheumatoid Arthritis Are Associated with Autoantibody Status. J Rheumatol. 2016;43:1008-16 pubmed publisher
Terawaki S, Camosseto V, Prete F, Wenger T, Papadopoulos A, Rondeau C, et al. RUN and FYVE domain-containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4. J Cell Biol. 2015;210:1133-52 pubmed publisher
Rider P, Carmi Y, Yossef R, Guttman O, Eini H, Azam T, et al. IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation. J Immunol. 2015;195:1705-12 pubmed publisher
Braun M, Björkström N, Gupta S, Sundström K, Ahlm C, Klingström J, et al. NK cell activation in human hantavirus infection explained by virus-induced IL-15/IL15Rα expression. PLoS Pathog. 2014;10:e1004521 pubmed publisher
De Keersmaecker B, Allard S, Lacor P, Schots R, Thielemans K, Aerts J. Expansion of polyfunctional HIV-specific T cells upon stimulation with mRNA electroporated dendritic cells in the presence of immunomodulatory drugs. J Virol. 2012;86:9351-60 pubmed publisher
product information
Antigen :
CD107a
Apps. Abbrev. :
Flow Cytometry
Cat # :
328626
Clone :
H4A3
Item :
Brilliant Violet 421™ anti-human CD107a (LAMP-1)
Isotype :
Mouse IgG1, κ
Other Names :
Lysosome-Associated Membrane Protein 1, LGP-120, LAMP-1
Size :
100 tests
Price (USD) :
396 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV421
Immunogen :
Human adult adherent peripheral blood cells
Application Notes :
Additional reported applications (for the relevant formats) include: Western blotting 8 , immunohistochemical staining 2 , immunofluorescence 5,7 , and immunoprecipitation 5 . This antibody is specific to human LAMP-1. Positive control: Hela cells; LAMP-1 molecular weight appears to be at about 110 kDa on the gel due to high glycosylation.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA