product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-human CD107a (LAMP-1)
catalog :
328611
quantity :
25 tests
price :
141 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF647
clone name :
H4A3
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200; loading ...; fig s2a
Okumura G, Iguchi Manaka A, Murata R, Yamashita Kanemaru Y, Shibuya A, Shibuya K. Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells. J Exp Med. 2020;217: pubmed publisher
  • flow cytometry; human; loading ...; fig 6d
Lynn R, Weber E, Sotillo E, Gennert D, Xu P, Good Z, et al. c-Jun overexpression in CAR T cells induces exhaustion resistance. Nature. 2019;576:293-300 pubmed publisher
  • flow cytometry; human; loading ...; fig 4d
Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed publisher
Avia M, Rojas J, Miorin L, Pascual E, van Rijn P, Martin V, et al. Virus-induced autophagic degradation of STAT2 as a mechanism for interferon signaling blockade. EMBO Rep. 2019;20:e48766 pubmed publisher
Monel B, McKeon A, Lamothe Molina P, Jani P, Boucau J, Pacheco Y, et al. HIV Controllers Exhibit Effective CD8+ T Cell Recognition of HIV-1-Infected Non-activated CD4+ T Cells. Cell Rep. 2019;27:142-153.e4 pubmed publisher
Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed publisher
Raj D, Yang M, Rodgers D, Hampton E, Begum J, Mustafa A, et al. Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma. Gut. 2018;: pubmed publisher
Carisey A, Mace E, Saeed M, Davis D, Orange J. Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells. Curr Biol. 2018;28:489-502.e9 pubmed publisher
Okada Y, Kimura T, Nakagawa T, Okamoto K, Fukuya A, Goji T, et al. EGFR Downregulation after Anti-EGFR Therapy Predicts the Antitumor Effect in Colorectal Cancer. Mol Cancer Res. 2017;15:1445-1454 pubmed publisher
Villarroya Beltri C, Baixauli F, Mittelbrunn M, Fernandez Delgado I, Torralba D, Moreno Gonzalo O, et al. ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins. Nat Commun. 2016;7:13588 pubmed publisher
Krishna B, Lau B, Jackson S, Wills M, Sinclair J, Poole E. Transient activation of human cytomegalovirus lytic gene expression during latency allows cytotoxic T cell killing of latently infected cells. Sci Rep. 2016;6:24674 pubmed publisher
Terahara K, Ishii H, Nomura T, Takahashi N, Takeda A, Shiino T, et al. Vaccine-induced CD107a+ CD4+ T cells are resistant to depletion following AIDS virus infection. J Virol. 2014;88:14232-40 pubmed publisher
Salio M, Ghadbane H, Dushek O, Shepherd D, Cypen J, Gileadi U, et al. Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation. Proc Natl Acad Sci U S A. 2013;110:E4753-61 pubmed publisher
De Keersmaecker B, Allard S, Lacor P, Schots R, Thielemans K, Aerts J. Expansion of polyfunctional HIV-specific T cells upon stimulation with mRNA electroporated dendritic cells in the presence of immunomodulatory drugs. J Virol. 2012;86:9351-60 pubmed publisher
Baron Gaillard C, Pallesi Pocachard E, Massey Harroche D, Richard F, Arsanto J, Chauvin J, et al. Hook2 is involved in the morphogenesis of the primary cilium. Mol Biol Cell. 2011;22:4549-62 pubmed publisher
Watanabe A, Tatematsu M, Saeki K, Shibata S, Shime H, Yoshimura A, et al. Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation. J Biol Chem. 2011;286:10702-11 pubmed publisher
product information
Antigen :
CD107a
Apps. Abbrev. :
Flow Cytometry
Cat # :
328611
Clone :
H4A3
Item :
Alexa Fluor® 647 anti-human CD107a (LAMP-1)
Isotype :
Mouse IgG1, κ
Other Names :
Lysosome-Associated Membrane Protein 1, LGP-120, LAMP-1
Size :
25 tests
Price (USD) :
141 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A647
Immunogen :
Human adult adherent peripheral blood cells
Application Notes :
Additional reported applications (for the relevant formats) include: Western blotting 8 , immunohistochemical staining 2 , immunofluorescence 5,7 , and immunoprecipitation 5 . This antibody is specific to human LAMP-1. Positive control: Hela cells; LAMP-1 molecular weight appears to be at about 110 kDa on the gel due to high glycosylation.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA