product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-human CD107a (LAMP-1)
catalog :
328606
quantity :
100 tests
price :
226 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
H4A3
reactivity :
human
application :
flow cytometry
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:200; loading ...; fig 5d
Bennstein S, Weinhold S, Manser A, Scherenschlich N, Noll A, Raba K, et al. Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells. elife. 2020;9: pubmed publisher
  • flow cytometry; human; fig 4
Srivastava R, Khan A, Spencer D, Vahed H, Lopes P, Thai N, et al. HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgenic. J Immunol. 2015;194:2232-48 pubmed publisher
  • flow cytometry; human; fig 4
Khan A, Srivastava R, Spencer D, Garg S, Fremgen D, Vahed H, et al. Phenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpes. J Virol. 2015;89:3776-92 pubmed publisher
Bilich T, Nelde A, Heitmann J, Maringer Y, Roerden M, Bauer J, et al. T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals. Sci Transl Med. 2021;13: pubmed publisher
Bertulli C, Marzollo A, Doria M, Di Cesare S, La Scola C, Mencarelli F, et al. Expanding Phenotype of Schimke Immuno-Osseous Dysplasia: Congenital Anomalies of the Kidneys and of the Urinary Tract and Alteration of NK Cells. Int J Mol Sci. 2020;21: pubmed publisher
Nguyen M, Hosokawa K, Yoroidaka T, Maruyama H, Espinoza J, Elbadry M, et al. Resistance of KIR Ligand-Missing Leukocytes to NK Cells In Vivo in Patients with Acquired Aplastic Anemia. Immunohorizons. 2020;4:430-441 pubmed publisher
Ni J, Wang X, Stojanovic A, Zhang Q, Wincher M, Bühler L, et al. Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity. Immunity. 2020;52:1075-1087.e8 pubmed publisher
Bilich T, Nelde A, Bauer J, Walz S, Roerden M, Salih H, et al. Mass spectrometry-based identification of a B-cell maturation antigen-derived T-cell epitope for antigen-specific immunotherapy of multiple myeloma. Blood Cancer J. 2020;10:24 pubmed publisher
Xu H, Wang B, Ono M, Kagita A, Fujii K, Sasakawa N, et al. Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility. Cell Stem Cell. 2019;: pubmed publisher
Khan A, Srivastava R, Vahed H, Roy S, Walia S, Kim G, et al. Human Asymptomatic Epitope Peptide/CXCL10-Based Prime/Pull Vaccine Induces Herpes Simplex Virus-Specific Gamma Interferon-Positive CD107+ CD8+ T Cells That Infiltrate the Corneas and Trigeminal Ganglia of Humanized HLA Transgenic Rabbits and Protect . J Virol. 2018;92: pubmed publisher
Dockry E, O Leary S, Gleeson L, Lyons J, Keane J, Gray S, et al. Epigenetic induction of CD1d expression primes lung cancer cells for killing by invariant natural killer T cells. Oncoimmunology. 2018;7:e1428156 pubmed publisher
Pahl J, Koch J, Götz J, Arnold A, Reusch U, Gantke T, et al. CD16A Activation of NK Cells Promotes NK Cell Proliferation and Memory-Like Cytotoxicity against Cancer Cells. Cancer Immunol Res. 2018;6:517-527 pubmed publisher
Felices M, Lenvik A, McElmurry R, Chu S, Hinderlie P, Bendzick L, et al. Continuous treatment with IL-15 exhausts human NK cells via a metabolic defect. JCI Insight. 2018;3: pubmed publisher
Lettau M, Armbrust F, Dohmen K, Drews L, Poch T, Dietz M, et al. Mechanistic peculiarities of activation-induced mobilization of cytotoxic effector proteins in human T cells. Int Immunol. 2018;30:215-228 pubmed publisher
Giuliani E, Vassena L, Di Cesare S, Malagnino V, Desimio M, Andreoni M, et al. NK cells of HIV-1-infected patients with poor CD4+ T-cell reconstitution despite suppressive HAART show reduced IFN-? production and high frequency of autoreactive CD56bright cells. Immunol Lett. 2017;190:185-193 pubmed publisher
Burel J, Apte S, McCarthy J, Doolan D. Plasmodium vivax but Not Plasmodium falciparum Blood-Stage Infection in Humans Is Associated with the Expansion of a CD8+ T Cell Population with Cytotoxic Potential. PLoS Negl Trop Dis. 2016;10:e0005031 pubmed publisher
Davis Z, Cogswell A, Scott H, Mertsching A, Boucau J, Wambua D, et al. A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells. PLoS Pathog. 2016;12:e1005421 pubmed publisher
Schlecker E, Fiegler N, Arnold A, Altevogt P, Rose John S, Moldenhauer G, et al. Metalloprotease-mediated tumor cell shedding of B7-H6, the ligand of the natural killer cell-activating receptor NKp30. Cancer Res. 2014;74:3429-40 pubmed publisher
Hendricks D, Balfour H, Dunmire S, Schmeling D, Hogquist K, Lanier L. Cutting edge: NKG2C(hi)CD57+ NK cells respond specifically to acute infection with cytomegalovirus and not Epstein-Barr virus. J Immunol. 2014;192:4492-6 pubmed publisher
Salio M, Ghadbane H, Dushek O, Shepherd D, Cypen J, Gileadi U, et al. Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation. Proc Natl Acad Sci U S A. 2013;110:E4753-61 pubmed publisher
De Keersmaecker B, Allard S, Lacor P, Schots R, Thielemans K, Aerts J. Expansion of polyfunctional HIV-specific T cells upon stimulation with mRNA electroporated dendritic cells in the presence of immunomodulatory drugs. J Virol. 2012;86:9351-60 pubmed publisher
Tai Y, Horton H, Kong S, Pong E, Chen H, Cemerski S, et al. Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function. Blood. 2012;119:2074-82 pubmed publisher
Baron Gaillard C, Pallesi Pocachard E, Massey Harroche D, Richard F, Arsanto J, Chauvin J, et al. Hook2 is involved in the morphogenesis of the primary cilium. Mol Biol Cell. 2011;22:4549-62 pubmed publisher
Watanabe A, Tatematsu M, Saeki K, Shibata S, Shime H, Yoshimura A, et al. Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation. J Biol Chem. 2011;286:10702-11 pubmed publisher
Kwant Mitchell A, Pek E, Rosenthal K, Ashkar A. Development of functional human NK cells in an immunodeficient mouse model with the ability to provide protection against tumor challenge. PLoS ONE. 2009;4:e8379 pubmed publisher
product information
Antigen :
CD107a
Apps. Abbrev. :
Flow Cytometry
Cat # :
328606
Clone :
H4A3
Item :
FITC anti-human CD107a (LAMP-1)
Isotype :
Mouse IgG1, κ
Other Names :
Lysosome-Associated Membrane Protein 1, LGP-120, LAMP-1
Size :
100 tests
Price (USD) :
226 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
FITC
Immunogen :
Human adult adherent peripheral blood cells
Application Notes :
Additional reported applications (for the relevant formats) include: Western blotting 8 , immunohistochemical staining 2 , immunofluorescence 5,7 , and immunoprecipitation 5 . This antibody is specific to human LAMP-1. Positive control: Hela cells; LAMP-1 molecular weight appears to be at about 110 kDa on the gel due to high glycosylation.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA