product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human CD107a (LAMP-1)
catalog :
328602
quantity :
100 μg
price :
114 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H4A3
reactivity :
human, mouse, pigs
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200; loading ...; fig s2a
Okumura G, Iguchi Manaka A, Murata R, Yamashita Kanemaru Y, Shibuya A, Shibuya K. Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells. J Exp Med. 2020;217: pubmed publisher
  • flow cytometry; human; loading ...; fig 6d
Lynn R, Weber E, Sotillo E, Gennert D, Xu P, Good Z, et al. c-Jun overexpression in CAR T cells induces exhaustion resistance. Nature. 2019;576:293-300 pubmed publisher
  • flow cytometry; human; loading ...; fig 4d
Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed publisher
  • immunocytochemistry; pigs ; fig 3e
Kober A, Manavalan A, Tam Amersdorfer C, Holmér A, Saeed A, Fanaee Danesh E, et al. Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier. Biochim Biophys Acta Mol Cell Biol Lipids. 2017;1862:573-588 pubmed publisher
  • flow cytometry; human; loading ...; fig 6a
Demers K, Makedonas G, Buggert M, Eller M, Ratcliffe S, Goonetilleke N, et al. Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection. PLoS Pathog. 2016;12:e1005805 pubmed publisher
  • flow cytometry; human; fig 1
Leeansyah E, Svärd J, Dias J, Buggert M, Nyström J, Quigley M, et al. Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. PLoS Pathog. 2015;11:e1005072 pubmed publisher
  • flow cytometry; human
Axelsson Robertson R, Rao M, Loxton A, Walzl G, Bates M, Zumla A, et al. Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment. Int J Infect Dis. 2015;32:23-9 pubmed publisher
  • flow cytometry; human
Axelsson Robertson R, Ju J, Kim H, Zumla A, Maeurer M. Mycobacterium tuberculosis-specific and MHC class I-restricted CD8+ T-cells exhibit a stem cell precursor-like phenotype in patients with active pulmonary tuberculosis. Int J Infect Dis. 2015;32:13-22 pubmed publisher
  • flow cytometry; human; fig 4
Srivastava R, Khan A, Spencer D, Vahed H, Lopes P, Thai N, et al. HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgenic. J Immunol. 2015;194:2232-48 pubmed publisher
  • flow cytometry; human; fig 4
Khan A, Srivastava R, Spencer D, Garg S, Fremgen D, Vahed H, et al. Phenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpes. J Virol. 2015;89:3776-92 pubmed publisher
  • flow cytometry; human; loading ...; fig 3d
van der Waart A, van de Weem N, Maas F, Kramer C, Kester M, Falkenburg J, et al. Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy. Blood. 2014;124:3490-500 pubmed publisher
Mendler A, Pierzchalski A, Bauer M, Roder S, Sattler A, Standl M, et al. MAIT cell activation in adolescents is impacted by bile acid concentrations and body weight. Clin Exp Immunol. 2020;200:199-213 pubmed publisher
Carlsten M, Namazi A, Reger R, Levy E, Berg M, St Hilaire C, et al. Bortezomib sensitizes multiple myeloma to NK cells via ER-stress-induced suppression of HLA-E and upregulation of DR5. Oncoimmunology. 2019;8:e1534664 pubmed publisher
Baranov M, Bianchi F, Schirmacher A, van Aart M, Maassen S, Muntjewerff E, et al. The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation. iScience. 2019;11:160-177 pubmed publisher
Sonnenschein H, Lawrence K, Wittenberg K, Slykas F, Dohleman E, Knoublauch J, et al. Suppressor of IKKepsilon forms direct interactions with cytoskeletal proteins, tubulin and α-actinin, linking innate immunity to the cytoskeleton. FEBS Open Bio. 2018;8:1064-1082 pubmed publisher
Speir M, Authier Hall A, Brooks C, Farrand K, Compton B, Anderson R, et al. Glycolipid-peptide conjugate vaccines enhance CD8+ T cell responses against human viral proteins. Sci Rep. 2017;7:14273 pubmed publisher
Baranov M, Revelo N, Dingjan I, Maraspini R, ter Beest M, Honigmann A, et al. SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis. Cell Rep. 2016;17:1518-1531 pubmed publisher
Kabanova A, Sanseviero F, Candi V, Gamberucci A, Gozzetti A, Campoccia G, et al. Human Cytotoxic T Lymphocytes Form Dysfunctional Immune Synapses with B Cells Characterized by Non-Polarized Lytic Granule Release. Cell Rep. 2016;15:9-18 pubmed publisher
Salio M, Ghadbane H, Dushek O, Shepherd D, Cypen J, Gileadi U, et al. Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation. Proc Natl Acad Sci U S A. 2013;110:E4753-61 pubmed publisher
De Keersmaecker B, Allard S, Lacor P, Schots R, Thielemans K, Aerts J. Expansion of polyfunctional HIV-specific T cells upon stimulation with mRNA electroporated dendritic cells in the presence of immunomodulatory drugs. J Virol. 2012;86:9351-60 pubmed publisher
Baron Gaillard C, Pallesi Pocachard E, Massey Harroche D, Richard F, Arsanto J, Chauvin J, et al. Hook2 is involved in the morphogenesis of the primary cilium. Mol Biol Cell. 2011;22:4549-62 pubmed publisher
Watanabe A, Tatematsu M, Saeki K, Shibata S, Shime H, Yoshimura A, et al. Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation. J Biol Chem. 2011;286:10702-11 pubmed publisher
product information
Antigen :
CD107a
Apps. Abbrev. :
Flow Cytometry, ICC, Western Blotting, IHC-P, IP
Cat # :
328602
Clone :
H4A3
Item :
Purified anti-human CD107a (LAMP-1)
Isotype :
Mouse IgG1, κ
Other Names :
Lysosome-Associated Membrane Protein 1, LGP-120, LAMP-1
Size :
100 μg
Price (USD) :
114 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
Human adult adherent peripheral blood cells
Application Notes :
Additional reported applications (for the relevant formats) include: Western blotting 8 , immunohistochemical staining 2 , immunofluorescence 5,7 , and immunoprecipitation 5 . This antibody is specific to human LAMP-1. Positive control: Hela cells; LAMP-1 molecular weight appears to be at about 110 kDa on the gel due to high glycosylation.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA