PE anti-human CD74 | BioLegend 326808 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human CD74

catalog :

326808

quantity :

100 tests

price :

268 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

LN2

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Reference
Song S, Manook M, Kwun J, Jackson A, Knechtle S, Kelsoe G. Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells. Front Immunol. 2021;12:705140 pubmed publisher
Kashima Y, Shibahara D, Suzuki A, Muto K, Kobayashi I, Plotnick D, et al. Single-cell analyses reveal diverse mechanisms of resistance to EGFR tyrosine kinase inhibitors in lung cancer. Cancer Res. 2021;: pubmed publisher
Obradovic A, Chowdhury N, Haake S, Ager C, Wang V, Vlahos L, et al. Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages. Cell. 2021;184:2988-3005.e16 pubmed publisher
Fujino S, Miyoshi N, Ito A, Yasui M, Ohue M, Ogino T, et al. Crenolanib regulates ERK and AKT/mTOR signaling pathways in RAS/BRAF-mutated colorectal cancer cells and organoids. Mol Cancer Res. 2021;: pubmed publisher
van Kempen T, Leijten E, Lindenbergh M, Nordkamp M, Driessen C, Lebbink R, et al. Impaired proteolysis by SPPL2a causes CD74 fragment accumulation that can be recognized by anti-CD74 autoantibodies in human ankylosing spondylitis. Eur J Immunol. 2020;50:1209-1219 pubmed publisher
Zimmerman K, Bentley M, Lever J, Li Z, Crossman D, Song C, et al. Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species. J Am Soc Nephrol. 2019;30:767-781 pubmed publisher
Aldeghaither D, Zahavi D, Murray J, Fertig E, Graham G, Zhang Y, et al. A Mechanism of Resistance to Antibody-Targeted Immune Attack. Cancer Immunol Res. 2019;7:230-243 pubmed publisher
Kong X, Martinez Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick E, et al. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nat Immunol. 2018;19:973-985 pubmed publisher
Morris K, Nofchissey R, Pinchuk I, Beswick E. Chronic macrophage migration inhibitory factor exposure induces mesenchymal epithelial transition and promotes gastric and colon cancers. PLoS ONE. 2014;9:e98656 pubmed publisher
Fernandez Cuesta L, Plenker D, Osada H, Sun R, Menon R, Leenders F, et al. CD74-NRG1 fusions in lung adenocarcinoma. Cancer Discov. 2014;4:415-22 pubmed publisher
Tarnowski M, Grymula K, Liu R, Tarnowska J, Drukala J, Ratajczak J, et al. Macrophage migration inhibitory factor is secreted by rhabdomyosarcoma cells, modulates tumor metastasis by binding to CXCR4 and CXCR7 receptors and inhibits recruitment of cancer-associated fibroblasts. Mol Cancer Res. 2010;8:1328-43 pubmed publisher

product information

Antigen :

CD74

Apps. Abbrev. :

Cat # :

326808

Clone :

LN2

Item :

PE anti-human CD74

Isotype :

Mouse IgG1, κ

Other Names :

MHC Class II associated invariant chain, invariant chain, Ii, MHC class II chaperone, MIF receptor

Size :

100 tests

Price (USD) :

268 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Immunogen :

SU-DHL-4 cells

Application Notes :

Clone LN2 is reactive with an epitope residing within 60 amino acids of the extracytoplasmic, COOH terminus of the protein.^3Additional reported applications (for the relevant formats) include: immunohistochemical staining^1,2 of frozen sections and formalin-fixed paraffin-embedded sections^1,2, immunoprecipitation^1, and immunofluorescence^4.;

more info or order :

BioLegend product webpage