LEAF™ Purified anti-human CD337 (NKp30) | BioLegend 325203 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

LEAF™ Purified anti-human CD337 (NKp30)

catalog :

325203

quantity :

50 μg

price :

130 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P30-15

reactivity :

human, Rhesus monkey

application :

immunohistochemistry, neutralization, flow cytometry, blocking or activating experiments, mass cytometry

citations: 14

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s2a	van Erp E, Feyaerts D, Duijst M, Mulder H, Wicht O, Luytjes W, et al. Respiratory Syncytial Virus Infects Primary Neonatal and Adult Natural Killer Cells and Affects Their Antiviral Effector Function. J Infect Dis. 2019;219:723-733 pubmed publisher
blocking or activating experiments; human; 10 ug/ml; loading ...; fig s3e	Srpan K, Ambrose A, Karampatzakis A, Saeed M, Cartwright A, Guldevall K, et al. Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells. J Cell Biol. 2018;217:3267-3283 pubmed publisher
immunohistochemistry; human; 5 mg/ml; loading ...; fig s1b	Carisey A, Mace E, Saeed M, Davis D, Orange J. Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells. Curr Biol. 2018;28:489-502.e9 pubmed publisher
flow cytometry; human; loading ...; fig s3c	Cribbs A, Hookway E, Wells G, Lindow M, Obad S, Oerum H, et al. Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells. J Biol Chem. 2018;293:2422-2437 pubmed publisher
mass cytometry; human; loading ...; fig 4f	Herndler Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, et al. Humanized mouse model supports development, function, and tissue residency of human natural killer cells. Proc Natl Acad Sci U S A. 2017;114:E9626-E9634 pubmed publisher
	Ye W, Chew M, Hou J, Lai F, Leopold S, Loo H, et al. Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway. PLoS Pathog. 2018;14:e1007298 pubmed publisher
	Walwyn Brown K, Guldevall K, Saeed M, Pende D, Önfelt B, MacDonald A, et al. Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1. J Immunol. 2018;201:2028-2041 pubmed publisher
	Desimio M, Giuliani E, Ferraro A, Adorno G, Doria M. In Vitro Exposure to Prostratin but Not Bryostatin-1 Improves Natural Killer Cell Functions Including Killing of CD4+ T Cells Harboring Reactivated Human Immunodeficiency Virus. Front Immunol. 2018;9:1514 pubmed publisher
	Vargas Hernandez A, Mace E, Zimmerman O, Zerbe C, Freeman A, Rosenzweig S, et al. Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations. J Allergy Clin Immunol. 2018;141:2142-2155.e5 pubmed publisher
	Cruz González D, Gómez Martín D, Layseca Espinosa E, Baranda L, Abud Mendoza C, Alcocer Varela J, et al. Analysis of the regulatory function of natural killer cells from patients with systemic lupus erythematosus. Clin Exp Immunol. 2017;: pubmed publisher
	Streltsova M, Barsov E, Erokhina S, Kovalenko E. Retroviral gene transfer into primary human NK cells activated by IL-2 and K562 feeder cells expressing membrane-bound IL-21. J Immunol Methods. 2017;450:90-94 pubmed publisher
	Cichocki F, Valamehr B, Bjordahl R, Zhang B, Rezner B, Rogers P, et al. GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity. Cancer Res. 2017;77:5664-5675 pubmed publisher
	Correia D, Fogli M, Hudspeth K, da Silva M, Mavilio D, Silva Santos B. Differentiation of human peripheral blood V?1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells. Blood. 2011;118:992-1001 pubmed publisher
	Manaster I, Mizrahi S, Goldman Wohl D, Sela H, Stern Ginossar N, Lankry D, et al. Endometrial NK cells are special immature cells that await pregnancy. J Immunol. 2008;181:1869-76 pubmed

product information

Antigen :

CD337

Apps. Abbrev. :

Flow Cytometry, ELISA, Block

Cat # :

325203

Clone :

P30-15

Item :

LEAF™ Purified anti-human CD337 (NKp30)

Isotype :

Mouse IgG1, κ

Other Names :

NKp30, NCR3, Activating NK receptor NKp30, natural cytotoxicity triggering receptor 3

Size :

50 μg

Price (USD) :

130 USD

Reactivity :

Human, African Green, Baboon, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

LEAF

Immunogen :

Recombinant human NKp30

Application Notes :

Additional reported applications (for the relevant formats) include: ELISA, stimulation of human NK cells via NKp30 in a redirected lysis assay, and blocking of NKp30 function in solution 1,3,5 . The Ultra-LEAF™ purified antibody (Endotoxin 0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. Nos. 325223 325224).