APC anti-human CD172a/b (SIRPα/β) | BioLegend 323810 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human CD172a/b (SIRPα/β)

catalog :

323810

quantity :

100 tests

price :

303 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

SE5A5

reactivity :

human, rat

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; rat; loading ...; fig 1a	Yang X, Zhou J, He J, Liu J, Wang H, Liu Y, et al. An Immune System-Modified Rat Model for Human Stem Cell Transplantation Research. Stem Cell Reports. 2018;11:514-521 pubmed publisher
flow cytometry; human; loading ...; fig s1b	Lopes F, BÃ¡lint Å, Valvo S, Felce J, Hessel E, Dustin M, et al. Membrane nanoclusters of FcÎ³RI segregate from inhibitory SIRPÎ± upon activation of human macrophages. J Cell Biol. 2017;216:1123-1141 pubmed publisher
	Chakraborty M, Chu K, Shrestha A, Revelo X, Zhang X, Gold M, et al. Mechanical Stiffness Controls Dendritic Cell Metabolism and Function. Cell Rep. 2021;34:108609 pubmed publisher
	Evans R, Antonelou M, Sathiananthamoorthy S, Rega M, Henderson S, Ceron Gutierrez L, et al. Inherited salt-losing tubulopathies are associated with immunodeficiency due to impaired IL-17 responses. Nat Commun. 2020;11:4368 pubmed publisher
	Gruber C, Calis J, Buta S, Evrony G, Martin J, Uhl S, et al. Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function. Immunity. 2020;53:672-684.e11 pubmed publisher
	Antonucci L, Porcu C, Timperi E, Santini S, Iannucci G, Balsano C. Circulating Neutrophils of Nonalcoholic Steatohepatitis Patients Show an Activated Phenotype and Suppress T Lymphocytes Activity. J Immunol Res. 2020;2020:4570219 pubmed publisher
	Hataye J, Casazza J, Best K, Liang C, Immonen T, Ambrozak D, et al. Principles Governing Establishment versus Collapse of HIV-1 Cellular Spread. Cell Host Microbe. 2019;26:748-763.e20 pubmed publisher
	Huang B, Chen Z, Geng L, Wang J, Liang H, Cao Y, et al. Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways. Cell. 2019;179:1160-1176.e24 pubmed publisher
	Findlay E, Currie A, Zhang A, Ovciarikova J, Young L, Stevens H, et al. Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy. Oncoimmunology. 2019;8:1608106 pubmed publisher

product information

Antigen :

CD172a/b

Apps. Abbrev. :

Cat # :

323810

Clone :

SE5A5

Item :

APC anti-human CD172a/b (SIRPα/β)

Isotype :

Mouse IgG1, κ

Other Names :

SIRPa, SIRPb, SIRPalpha/beta, BIT, SHPS1, MFR, P84, PTPNS1, CD172 antigen-like family member A, CD172 antigen-like family member B

Size :

100 tests

Price (USD) :

303 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC

Immunogen :

NIH-3T3/hu-SIRPα cell line

Application Notes :

Clone SE5A5 recognizes a common epitope on SIRPa (90 kD) and SIRPß (50 kD)^3. A high degree of homology has been found between SIRP family isoforms alpha and beta at the level of extracellular domains. Consequently, many anti SIRP antibody clones, such as SE5A5, have been reported to cross react with several SIRP isoforms^1,4,5. It reacts with CD172a and has weak cross-reaction with CD172b. This antibody is able to block the binding of SIRPa (SIRPa1 and SIRPa2) to CD47^1,6.;

more info or order :

BioLegend product webpage