PE anti-human CD172a/b (SIRPα/β) | BioLegend 323805 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human CD172a/b (SIRPα/β)

catalog :

323805

quantity :

25 tests

price :

122 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

SE5A5

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 3	Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed publisher
	Wang B, Nash T, Zhang X, Rao J, Abriola L, Kim Y, et al. Engineered cardiac tissue model of restrictive cardiomyopathy for drug discovery. Cell Rep Med. 2023;4:100976 pubmed publisher
	Zhang X, Wang B, Kim M, Nash T, Liu B, Rao J, et al. STK25 inhibits PKA signaling by phosphorylating PRKAR1A. Cell Rep. 2022;40:111203 pubmed publisher
	Cytlak U, Resteu A, Pagan S, Green K, Milne P, Maisuria S, et al. Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans. Immunity. 2020;53:353-370.e8 pubmed publisher
	Fu J, Zuber J, Martinez M, Shonts B, Obradovic A, Wang H, et al. Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool. Cell Stem Cell. 2019;24:227-239.e8 pubmed publisher
	Barman S, Kayama H, Okuzaki D, Ogino T, Osawa H, Matsuno H, et al. Identification of a human intestinal myeloid cell subset that regulates gut homeostasis. Int Immunol. 2016;28:533-545 pubmed

product information

Antigen :

CD172a/b

Apps. Abbrev. :

Cat # :

323805

Clone :

SE5A5

Item :

PE anti-human CD172a/b (SIRPα/β)

Isotype :

Mouse IgG1, κ

Other Names :

SIRPa, SIRPb, SIRPalpha/beta, BIT, SHPS1, MFR, P84, PTPNS1, CD172 antigen-like family member A, CD172 antigen-like family member B

Size :

25 tests

Price (USD) :

122 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Immunogen :

NIH-3T3/hu-SIRPα cell line

Application Notes :

Clone SE5A5 recognizes a common epitope on SIRPa (90 kD) and SIRPß (50 kD)^3. A high degree of homology has been found between SIRP family isoforms alpha and beta at the level of extracellular domains. Consequently, many anti SIRP antibody clones, such as SE5A5, have been reported to cross react with several SIRP isoforms^1,4,5. It reacts with CD172a and has weak cross-reaction with CD172b. This antibody is able to block the binding of SIRPa (SIRPa1 and SIRPa2) to CD47^1,6.;

more info or order :

BioLegend product webpage