product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-human CD47
catalog :
323106
quantity :
100 tests
price :
229 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
CC2C6
reactivity :
human
application :
flow cytometry
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s8b
DeWeirdt P, Sanson K, Sangree A, Hegde M, Hanna R, Feeley M, et al. Optimization of AsCas12a for combinatorial genetic screens in human cells. Nat Biotechnol. 2020;: pubmed publisher
  • flow cytometry; human; loading ...; fig 1b
Logtenberg M, Jansen J, Raaben M, Toebes M, Franke K, Brandsma A, et al. Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy. Nat Med. 2019;25:612-619 pubmed publisher
Hu X, White K, Olroyd A, Dejesus R, Dominguez A, Dowdle W, et al. Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques. Nat Biotechnol. 2023;: pubmed publisher
Hu X, Manner K, Dejesus R, White K, Gattis C, Ngo P, et al. Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice. Nat Commun. 2023;14:2020 pubmed publisher
Falc xf3 n Cama V, Montero Gonz xe1 lez T, Acosta Medina E, Guillen Nieto G, Berlanga Acosta J, Fern xe1 ndez Ortega C, et al. Evidence of SARS-CoV-2 infection in postmortem lung, kidney, and liver samples, revealing cellular targets involved in COVID-19 pathogenesis. Arch Virol. 2023;168:96 pubmed publisher
Li M, Yu H, Qi F, Ye Y, Hu D, Cao J, et al. Anti-CD47 immunotherapy in combination with BCL-2 inhibitor to enhance anti-tumor activity in B-cell lymphoma. Hematol Oncol. 2022;40:596-608 pubmed publisher
Wang H, Wen C, Chen S, Li W, Qin Q, He L, et al. ROS/JNK/C-Jun Pathway is Involved in Chaetocin Induced Colorectal Cancer Cells Apoptosis and Macrophage Phagocytosis Enhancement. Front Pharmacol. 2021;12:729367 pubmed publisher
Cantoni C, Serra M, Parisi E, Azzarone B, Sementa A, Nasto L, et al. Stromal-like Wilms tumor cells induce human Natural Killer cell degranulation and display immunomodulatory properties towards NK cells. Oncoimmunology. 2021;10:1879530 pubmed publisher
Burgess T, Amason J, Rubin J, Duveau D, Lamy L, Roberts D, et al. A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology. PLoS ONE. 2020;15:e0226661 pubmed publisher
Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, et al. Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin. elife. 2020;9: pubmed publisher
Barrera L, Montes Servín E, Hernandez Martinez J, García Vicente M, Montes Servín E, Herrera Martínez M, et al. CD47 overexpression is associated with decreased neutrophil apoptosis/phagocytosis and poor prognosis in non-small-cell lung cancer patients. Br J Cancer. 2017;117:385-397 pubmed publisher
product information
Antigen :
CD47
Apps. Abbrev. :
FC
Cat # :
323106
Clone :
CC2C6
Item :
FITC anti-human CD47
Isotype :
Mouse IgG1, κ
Other Names :
Rh-associated protein, gp42, integrin-associated protein, IAP, neurophilin
Size :
100 tests
Price (USD) :
229 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
FITC
Immunogen :
CCRF-CEM T-cell line
Application Notes :
The CC2C6 monoclonal antibody can block the binding of HCD47 antibody to CD47.Additional reported applications (for the relevant formats) include: blocking^2;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA