product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-human CD47
catalog :
323102
quantity :
100 μg
price :
118 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CC2C6
reactivity :
human, mouse
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2b
Logtenberg M, Jansen J, Raaben M, Toebes M, Franke K, Brandsma A, et al. Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy. Nat Med. 2019;25:612-619 pubmed publisher
  • flow cytometry; mouse; loading ...; fig e5d
Chen J, Zhong M, Guo H, Davidson D, Mishel S, Lu Y, et al. SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin. Nature. 2017;544:493-497 pubmed publisher
Safari H, Felder M, Kaczorowski N, Eniola Adefeso O. Effect of the Emulsion Solvent Evaporation Technique Cosolvent Choice on the Loading Efficiency and Release Profile of Anti-CD47 from PLGA Nanospheres. J Pharm Sci. 2022;111:2525-2530 pubmed publisher
Ganan Gomez I, Yang H, Ma F, Montalban Bravo G, Thongon N, Marchica V, et al. Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy. Nat Med. 2022;28:557-567 pubmed publisher
Mezzapelle R, De Marchis F, Passera C, Leo M, Brambilla F, Colombo F, et al. CXCR4 engagement triggers CD47 internalization and antitumor immunization in a mouse model of mesothelioma. EMBO Mol Med. 2021;13:e12344 pubmed publisher
Mooney R, Abidi W, Batalla Covello J, Ngai H, Hyde C, Machado D, et al. Allogeneic human neural stem cells for improved therapeutic delivery to peritoneal ovarian cancer. Stem Cell Res Ther. 2021;12:205 pubmed publisher
Burgess T, Amason J, Rubin J, Duveau D, Lamy L, Roberts D, et al. A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology. PLoS ONE. 2020;15:e0226661 pubmed publisher
Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, et al. Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin. elife. 2020;9: pubmed publisher
Mair B, Aldridge P, Atwal R, Philpott D, Zhang M, Masud S, et al. High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting. Nat Biomed Eng. 2019;3:796-805 pubmed publisher
Thier M, Hommerding O, Panten J, Pinna R, García González D, Berger T, et al. Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells. Cell Stem Cell. 2019;24:166-182.e13 pubmed publisher
Barrera L, Montes Servín E, Hernandez Martinez J, García Vicente M, Montes Servín E, Herrera Martínez M, et al. CD47 overexpression is associated with decreased neutrophil apoptosis/phagocytosis and poor prognosis in non-small-cell lung cancer patients. Br J Cancer. 2017;117:385-397 pubmed publisher
McCauley K, Hawkins F, Serra M, Thomas D, JACOB A, Kotton D. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell. 2017;20:844-857.e6 pubmed publisher
Mao T, Fu L, Wang J. Hypoxic exercise training causes erythrocyte senescence and rheological dysfunction by depressed Gardos channel activity. J Appl Physiol (1985). 2011;111:382-91 pubmed publisher
product information
Antigen :
CD47
Apps. Abbrev. :
FC, ICC
Cat # :
323102
Clone :
CC2C6
Item :
Purified anti-human CD47
Isotype :
Mouse IgG1, κ
Other Names :
Rh-associated protein, gp42, integrin-associated protein, IAP, neurophilin
Size :
100 μg
Price (USD) :
118 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PURE
Immunogen :
CCRF-CEM T-cell line
Application Notes :
The CC2C6 monoclonal antibody can block the binding of HCD47 antibody to CD47.Additional reported applications (for the relevant formats) include: blocking^2;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA