PE anti-human CD195 (CCR5) Phospho (Ser349) | BioLegend 321606 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human CD195 (CCR5) Phospho (Ser349)

catalog :

321606

quantity :

100 tests

price :

317 USD

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

E11/19

reactivity :

human

application :

immunocytochemistry

more info or order :

BioLegend product webpage

citations: 3

Reference
Huffman A, Richman L, Crisalli L, Ganetsky A, Porter D, Vonderheide R, et al. Pharmacodynamic Monitoring Predicts Outcomes of CCR5 Blockade as Graft-versus-Host Disease Prophylaxis. Biol Blood Marrow Transplant. 2018;24:594-599 pubmed publisher
Scalley Kim M, Hess B, Kelly R, Krostag A, Lustig K, Marken J, et al. A novel highly potent therapeutic antibody neutralizes multiple human chemokines and mimics viral immune modulation. PLoS ONE. 2012;7:e43332 pubmed publisher
Dahl M, Berson A, Lora J, Fuentes M. A novel CCR5-specific pharmacodynamic assay in whole blood using phosphoflow cytometry highlights different ligand-dependent responses but similar properties of antagonists in CD8+ and CD4+ T lymphocytes. J Pharmacol Exp Ther. 2008;327:926-33 pubmed publisher

product information

Antigen :

CD195 Phospho Ser349

Apps. Abbrev. :

ICFC

Cat # :

321606

Clone :

E11/19

Item :

PE anti-human CD195 (CCR5) Phospho (Ser349)

Isotype :

Mouse IgG1, κ

Other Names :

CD195, CCR5, C-C chemokine receptor type 5, HIV-1 fusion co-receptor

Size :

100 tests

Price (USD) :

317 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Immunogen :

Phosphopeptide (CEAPERA(pS)(pS)VYTR(pS)TGEQI(pS)VGL) of CCR5

Application Notes :

The E11/19 monoclonal antibody binds to phosphoserine 349 corresponding to 22 c-terminal amino acid residues of human CCR5 and is useful for flow cytometric analysis, immunoblotting, and ELISA assay of CCR5 expression. Additional reported applications (for the relevant formats) include: immunofluorescence microscopy^1, and ELISA detection^1 when paired with T21/8 as the capture antibody (Cat. No. 321401/321402).;

more info or order :

BioLegend product webpage