product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-human/mouse CLA
catalog :
321310
quantity :
100 tests
price :
268 USD
clonality :
monoclonal
host :
rat
conjugate :
AF647
clone name :
HECA-452
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 6b
Szilagyi B, Triebus J, Kressler C, De Almeida M, Tierling S, Durek P, et al. Gut memories do not fade: epigenetic regulation of lasting gut homing receptor expression in CD4+ memory T cells. Mucosal Immunol. 2017;10:1443-1454 pubmed publisher
  • flow cytometry; human; fig 6b
Fu N, Rios A, Pal B, Law C, Jamieson P, Liu R, et al. Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive. Nat Cell Biol. 2017;19:164-176 pubmed publisher
Kuri Cervantes L, Pampena M, Betts M. Phenotypic Characterization of SLex+ and CLA+ CD4+ T Cells. STAR Protoc. 2020;1:100154 pubmed publisher
Colomb F, Giron L, Kuri Cervantes L, Adeniji O, Ma T, Dweep H, et al. Sialyl-LewisX Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy. Cell Rep. 2020;32:107991 pubmed publisher
Carrascal M, Talina C, Borralho P, Gonçalo Mineiro A, Henriques A, Pen C, et al. Staining of E-selectin ligands on paraffin-embedded sections of tumor tissue. BMC Cancer. 2018;18:495 pubmed publisher
Hensel M, Peng T, Cheng A, De Rosa S, Wald A, Laing K, et al. Selective Expression of CCR10 and CXCR3 by Circulating Human Herpes Simplex Virus-Specific CD8 T Cells. J Virol. 2017;91: pubmed publisher
Betts R, Perkovic A, Mahapatra S, Del Bufalo A, Camara K, Howell A, et al. Contact sensitizers trigger human CD1-autoreactive T-cell responses. Eur J Immunol. 2017;47:1171-1180 pubmed publisher
Tyler C, McCarthy N, Lindsay J, Stagg A, Moser B, Eberl M. Antigen-Presenting Human γδ T Cells Promote Intestinal CD4+ T Cell Expression of IL-22 and Mucosal Release of Calprotectin. J Immunol. 2017;198:3417-3425 pubmed publisher
Silva M, Fung R, Donnelly C, Videira P, Sackstein R. Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology. J Immunol. 2017;198:3576-3587 pubmed publisher
Boardman D, Philippeos C, Fruhwirth G, Ibrahim M, Hannen R, Cooper D, et al. Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection. Am J Transplant. 2017;17:931-943 pubmed publisher
Ren Y, Nong L, Zhang S, Zhao J, Zhang X, Li T. Analysis of 142 Northern Chinese patients with peripheral T/NK-Cell lymphomas: subtype distribution, clinicopathologic features, and prognosis. Am J Clin Pathol. 2012;138:435-47 pubmed publisher
product information
Antigen :
CLA
Apps. Abbrev. :
FC
Cat # :
321310
Clone :
HECA-452
Item :
Alexa Fluor® 647 anti-human/mouse CLA
Isotype :
Rat IgM, κ
Other Names :
Cutaneous Lymphocyte-associated Antigen (CLA)
Size :
100 tests
Price (USD) :
268 USD
Reactivity :
Human, Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A647
Application Notes :
The HECA-452 antibody cross-reacts with mouse skin homing lymphocytes^4. Treatment of activated HUVEC cells with HECA-452 antibody inhibits lymphocyte adhesion. Additional reported applications (for the relevant formats) include: blocking of lymphocyte binding to E-selectin^3, and immunohistochemistry^1,2 of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA