Pacific Blue™ anti-human/mouse CLA | BioLegend 321307 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Pacific Blue™ anti-human/mouse CLA

catalog :

321307

quantity :

25 μg

price :

124 USD

clonality :

monoclonal

host :

rat

conjugate :

Pacific Blue

clone name :

HECA-452

reactivity :

human, mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 4

Reference
Xu Y, Nipper M, Dominguez A, Ye Z, Akanuma N, Lopez K, et al. Reconstitution of human PDAC using primary cells reveals oncogenic transcriptomic features at tumor onset. Nat Commun. 2024;15:818 pubmed publisher
Nipper M, Xu Y, Liu J, Yin X, Liu Z, Ye Z, et al. TGFβ and Hippo Signaling Pathways Coordinate to Promote Acinar to Ductal Metaplasia in Human Pancreas. Cells. 2024;13: pubmed publisher
Mondal N, Silva M, Castano A, Maus M, Sackstein R. Glycoengineering of chimeric antigen receptor (CAR) T-cells to enforce E-selectin binding. J Biol Chem. 2019;294:18465-18474 pubmed publisher
Liu J, Akanuma N, Liu C, Naji A, Halff G, Washburn W, et al. TGF-?1 promotes acinar to ductal metaplasia of human pancreatic acinar cells. Sci Rep. 2016;6:30904 pubmed publisher

product information

Antigen :

CLA

Apps. Abbrev. :

Cat # :

321307

Clone :

HECA-452

Item :

Pacific Blue™ anti-human/mouse CLA

Isotype :

Rat IgM, κ

Other Names :

Cutaneous Lymphocyte-associated Antigen (CLA)

Size :

25 μg

Price (USD) :

124 USD

Reactivity :

Human, Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Application Notes :

The HECA-452 antibody cross-reacts with mouse skin homing lymphocytes^4. Treatment of activated HUVEC cells with HECA-452 antibody inhibits lymphocyte adhesion. Additional reported applications (for the relevant formats) include: blocking of lymphocyte binding to E-selectin^3, and immunohistochemistry^1,2 of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections.;

more info or order :

BioLegend product webpage