Alexa Fluor® 647 anti-human/mouse integrin β7 | BioLegend 321221 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 647 anti-human/mouse integrin β7

catalog :

321221

quantity :

25 tests

price :

147 USD

clonality :

monoclonal

host :

rat

conjugate :

AF647

clone name :

FIB504

reactivity :

human, mouse, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 2a	Tyler C, McCarthy N, Lindsay J, Stagg A, Moser B, Eberl M. Antigen-Presenting Human γδ T Cells Promote Intestinal CD4+ T Cell Expression of IL-22 and Mucosal Release of Calprotectin. J Immunol. 2017;198:3417-3425 pubmed publisher
flow cytometry; mouse; fig 2a	Yokota Nakatsuma A, Ohoka Y, Takeuchi H, Song S, Iwata M. Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties. Sci Rep. 2016;6:37914 pubmed publisher
	Sinclair L, Barthelemy C, Cantrell D. Single Cell Glucose Uptake Assays: A Cautionary Tale. Immunometabolism. 2020;2:e200029 pubmed publisher
	Chew H, De Lima P, Gonzalez Cruz J, Banushi B, Echejoh G, Hu L, et al. Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell. 2020;180:895-914.e27 pubmed publisher
	Daglas M, Draxler D, Ho H, McCutcheon F, Galle A, Au A, et al. Activated CD8+ T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice. Cell Rep. 2019;29:1178-1191.e6 pubmed publisher
	Risnes L, Christophersen A, Dahal Koirala S, Neumann R, Sandve G, Sarna V, et al. Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease. J Clin Invest. 2018;128:2642-2650 pubmed publisher
	Sun H, Lagarrigue F, Gingras A, Fan Z, Ley K, Ginsberg M. Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development. J Cell Biol. 2018;217:1453-1465 pubmed publisher
	Lee C, Zhang H, Singh S, Koo L, Kabat J, Tsang H, et al. C/EBPδ drives interactions between human MAIT cells and endothelial cells that are important for extravasation. elife. 2018;7: pubmed publisher
	den Hartog G, van Osch T, Vos M, Meijer B, Savelkoul H, van Neerven R, et al. BAFF augments IgA2 and IL-10 production by TLR7/8 stimulated total peripheral blood B cells. Eur J Immunol. 2018;48:283-292 pubmed publisher
	Boardman D, Philippeos C, Fruhwirth G, Ibrahim M, Hannen R, Cooper D, et al. Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection. Am J Transplant. 2017;17:931-943 pubmed publisher
	Ohmori K, Luo Y, Jia Y, Nishida J, Wang Z, Bunting K, et al. IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen. J Immunol. 2009;182:2835-41 pubmed publisher

product information

Antigen :

Integrin beta7

Apps. Abbrev. :

Cat # :

321221

Clone :

FIB504

Item :

Alexa Fluor® 647 anti-human/mouse integrin β7

Isotype :

Rat IgG2a, κ

Other Names :

β7 Integrin, integrin βp, ITGB7

Size :

25 tests

Price (USD) :

147 USD

Reactivity :

Human, Mouse, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

A647

Immunogen :

TK1 cells

Application Notes :

The FIB504 antibody has been reported to react with mouse and human ß7 integrin and to block ß7 integrin-mediated cell adhesion in in vitro and in vivo studies. Additional reported applications (for the relevant formats) include: blocking of cell adhesion^1,3,4. The Ultra-LEAF™ purified FIB504 antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 321233-321238).;

more info or order :

BioLegend product webpage