APC anti-human/mouse integrin β7 | BioLegend 321207 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human/mouse integrin β7

catalog :

321207

quantity :

25 tests

price :

149 USD

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

FIB504

reactivity :

human, mouse, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 5a	Sens C, Altrock E, Rau K, Klemis V, von Au A, Pettera S, et al. An O-Glycosylation of Fibronectin Mediates Hepatic Osteodystrophy Through α4β1 Integrin. J Bone Miner Res. 2017;32:70-81 pubmed publisher
	Lorvik K, Meyer Myklestad M, Kushekar K, Handeland C, Medhus A, Lund Iversen M, et al. Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4+ T Cells in HIV-Infected Immunological Non-Responders. Front Immunol. 2021;12:744155 pubmed publisher
	Sandborn W, Mattheakis L, Modi N, Pugatch D, Bressler B, Lee S, et al. PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis. Gastroenterology. 2021;161:1853-1864.e10 pubmed publisher
	Liu C, Gong Y, Zhang H, Yang H, Zeng Y, Bian Z, et al. Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells. Cell Res. 2021;: pubmed publisher
	Yan J, Pandey S, Barnes B, Turner J, Abraham C. T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation. Cell Rep. 2020;31:107820 pubmed publisher
	Chng M, Lim M, Rouers A, Becht E, Lee B, Macary P, et al. Large-Scale HLA Tetramer Tracking of T Cells during Dengue Infection Reveals Broad Acute Activation and Differentiation into Two Memory Cell Fates. Immunity. 2019;51:1119-1135.e5 pubmed publisher
	Sun H, Lagarrigue F, Gingras A, Fan Z, Ley K, Ginsberg M. Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development. J Cell Biol. 2018;217:1453-1465 pubmed publisher
	Cuenca M, Romero X, Sintes J, Terhorst C, Engel P. Targeting of Ly9 (CD229) Disrupts Marginal Zone and B1 B Cell Homeostasis and Antibody Responses. J Immunol. 2016;196:726-37 pubmed publisher
	Yamada D, Kadono T, Masui Y, Yanaba K, Sato S. ?7 Integrin controls mast cell recruitment, whereas ?E integrin modulates the number and function of CD8+ T cells in immune complex-mediated tissue injury. J Immunol. 2014;192:4112-21 pubmed publisher
	Hennion Tscheltzoff O, LeBoeuf D, Gauthier S, Dupuis M, Assouline B, Grégoire A, et al. TCR triggering modulates the responsiveness and homeostatic proliferation of CD4+ thymic emigrants to IL-7 therapy. Blood. 2013;121:4684-93 pubmed publisher
	Ohmori K, Luo Y, Jia Y, Nishida J, Wang Z, Bunting K, et al. IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen. J Immunol. 2009;182:2835-41 pubmed publisher

product information

Antigen :

Integrin beta7

Apps. Abbrev. :

Cat # :

321207

Clone :

FIB504

Item :

APC anti-human/mouse integrin β7

Isotype :

Rat IgG2a, κ

Other Names :

β7 Integrin, integrin βp, ITGB7

Size :

25 tests

Price (USD) :

149 USD

Reactivity :

Human, Mouse, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC

Immunogen :

TK1 cells

Application Notes :

The FIB504 antibody has been reported to react with mouse and human ß7 integrin and to block ß7 integrin-mediated cell adhesion in in vitro and in vivo studies. Additional reported applications (for the relevant formats) include: blocking of cell adhesion^1,3,4. The Ultra-LEAF™ purified FIB504 antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 321233-321238).;

more info or order :

BioLegend product webpage