PE anti-human/mouse integrin β7 | BioLegend 321204 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-human/mouse integrin β7

catalog :

321204

quantity :

100 tests

price :

252 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

FIB504

reactivity :

human, mouse, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 6

Reference
Min H, Moon J, Lee S, Lee A, Lee C, Lee J, et al. Expanded IL-22+ Group 3 Innate Lymphoid Cells and Role of Oxidized LDL-C in the Pathogenesis of Axial Spondyloarthritis with Dyslipidaemia. Immune Netw. 2021;21:e43 pubmed publisher
Sandborn W, Mattheakis L, Modi N, Pugatch D, Bressler B, Lee S, et al. PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis. Gastroenterology. 2021;161:1853-1864.e10 pubmed publisher
Dai B, Hackney J, Ichikawa R, Nguyen A, Elstrott J, Orozco L, et al. Dual targeting of lymphocyte homing and retention through α4β7 and αEβ7 inhibition in inflammatory bowel disease. Cell Rep Med. 2021;2:100381 pubmed publisher
Kawamoto E, Nago N, Okamoto T, Gaowa A, Masui Ito A, Akama Y, et al. The Lectin-Like Domain of Thrombomodulin Inhibits β1 Integrin-Dependent Binding of Human Breast Cancer-Derived Cell Lines to Fibronectin. Biomedicines. 2021;9: pubmed publisher
Durant L, Stentz R, Noble A, Brooks J, Gicheva N, Reddi D, et al. Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease. Microbiome. 2020;8:88 pubmed publisher
Candia E, Reyes P, Covian C, Rodriguez F, Wainstein N, Morales J, et al. Single and combined effect of retinoic acid and rapamycin modulate the generation, activity and homing potential of induced human regulatory T cells. PLoS ONE. 2017;12:e0182009 pubmed publisher

product information

Antigen :

Integrin beta7

Apps. Abbrev. :

Cat # :

321204

Clone :

FIB504

Item :

PE anti-human/mouse integrin β7

Isotype :

Rat IgG2a, κ

Other Names :

β7 Integrin, integrin βp, ITGB7

Size :

100 tests

Price (USD) :

252 USD

Reactivity :

Human, Mouse, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

TK1 cells

Application Notes :

The FIB504 antibody has been reported to react with mouse and human ß7 integrin and to block ß7 integrin-mediated cell adhesion in in vitro and in vivo studies. Additional reported applications (for the relevant formats) include: blocking of cell adhesion^1,3,4. The Ultra-LEAF™ purified FIB504 antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 321233-321238).;

more info or order :

BioLegend product webpage