Ultra-LEAF™ Purified anti-human CD206 (MMR) | BioLegend 321149 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-human CD206 (MMR)

catalog :

321149

quantity :

100 μg

price :

270 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

15-2

reactivity :

human

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

BioLegend product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:100; loading ...; fig 4d, 7c	Beider K, Voevoda Dimenshtein V, Zoabi A, Rosenberg E, Magen H, Ostrovsky O, et al. CXCL13 chemokine is a novel player in multiple myeloma osteolytic microenvironment, M2 macrophage polarization, and tumor progression. J Hematol Oncol. 2022;15:144 pubmed publisher
flow cytometry; human; loading ...; fig s14b	Stewart B, Ferdinand J, Young M, Mitchell T, Loudon K, Riding A, et al. Spatiotemporal immune zonation of the human kidney. Science. 2019;365:1461-1466 pubmed publisher
flow cytometry; human; loading ...; fig 2a	Haque A, Moriyama M, Kubota K, Ishiguro N, Sakamoto M, Chinju A, et al. CD206+ tumor-associated macrophages promote proliferation and invasion in oral squamous cell carcinoma via EGF production. Sci Rep. 2019;9:14611 pubmed publisher
	Donado C, Cao A, Simmons D, Croker B, Brennan P, Brenner M. A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling. Cell Rep. 2020;31:107466 pubmed publisher

product information

Antigen :

CD206

Apps. Abbrev. :

FC, WB, ICC, IHC-F

Cat # :

321149

Clone :

15-2

Item :

Ultra-LEAF™ Purified anti-human CD206 (MMR)

Isotype :

Mouse IgG1, κ

Other Names :

MMR (macrophage mannose receptor), MR (mannose receptor), CD206, MRC1

Size :

100 μg

Price (USD) :

270 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ULEAF

Immunogen :

Purified human mannose receptor

Application Notes :

The 15-2 antibody blocks the interaction of MMR with its ligand, and inhibits mannose receptor-mediated degradation of t-PA by macrophages. Additional reported applications of this antibody (for the relevant formats) include: Western blotting^1, blocking of ligand binding^1,2, immunofluorescence^3, and immunohistochemical staining of acetone-fixed frozen tissue sections^1. The Utra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 321149 and 321150).;

more info or order :

BioLegend product webpage