PE/Cyanine7 anti-human CD206 (MMR) | BioLegend 321124 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Cyanine7 anti-human CD206 (MMR)

catalog :

321124

quantity :

100 tests

price :

317 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

15-2

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig s5i	Qin L, Wang L, Zhang J, Zhou H, Yang Z, Wang Y, et al. Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancer. Sci Adv. 2022;8:eabn3774 pubmed publisher
	Gu J, Chu X, Huo Y, Liu C, Chen Q, Hu S, et al. Gastric cancer-derived exosomes facilitate pulmonary metastasis by activating ERK-mediated immunosuppressive macrophage polarization. J Cell Biochem. 2023;124:557-572 pubmed publisher
	Yamaguchi Y, Gibson J, Ou K, Lopez L, Ng R, Leggett N, et al. PD-L1 blockade restores CAR T cell activity through IFN-γ-regulation of CD163+ M2 macrophages. J Immunother Cancer. 2022;10: pubmed publisher
	Wu Y, Jennings N, Sun Y, Dasari S, Bayraktar E, Corvigno S, et al. Targeting CCR2+ macrophages with BET inhibitor overcomes adaptive resistance to anti-VEGF therapy in ovarian cancer. J Cancer Res Clin Oncol. 2022;148:803-821 pubmed publisher
	Billing F, Walter B, Fink S, Arefaine E, Pickarski L, Maier S, et al. Altered Proinflammatory Responses to Polyelectrolyte Multilayer Coatings Are Associated with Differences in Protein Adsorption and Wettability. ACS Appl Mater Interfaces. 2021;13:55534-55549 pubmed publisher
	Mikhalkevich N, O Carroll I, Tkavc R, Lund K, Sukumar G, Dalgard C, et al. Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses. PLoS Pathog. 2021;17:e1009305 pubmed publisher
	Bryson B, Rosebrock T, Tafesse F, Itoh C, Nibasumba A, Babunovic G, et al. Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis. Nat Commun. 2019;10:2329 pubmed publisher
	Becker J, Kinast V, Döring M, Lipps C, Durán V, Spanier J, et al. Human monocyte-derived macrophages inhibit HCMV spread independent of classical antiviral cytokines. Virulence. 2018;9:1669-1684 pubmed publisher
	Lewis D, Petersen L, York A, Ahuja S, Chae H, Joseph L, et al. Nanotherapeutics for inhibition of atherogenesis and modulation of inflammation in atherosclerotic plaques. Cardiovasc Res. 2016;109:283-93 pubmed publisher

product information

Antigen :

CD206

Apps. Abbrev. :

Cat # :

321124

Clone :

15-2

Item :

PE/Cyanine7 anti-human CD206 (MMR)

Isotype :

Mouse IgG1, κ

Other Names :

MMR (macrophage mannose receptor), MR (mannose receptor), CD206, MRC1

Size :

100 tests

Price (USD) :

317 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PE_CYANINE7

Immunogen :

Purified human mannose receptor

Application Notes :

The 15-2 antibody blocks the interaction of MMR with its ligand, and inhibits mannose receptor-mediated degradation of t-PA by macrophages. Additional reported applications of this antibody (for the relevant formats) include: Western blotting^1, blocking of ligand binding^1,2, immunofluorescence^3, and immunohistochemical staining of acetone-fixed frozen tissue sections^1. The Utra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 321149 and 321150).;

more info or order :

BioLegend product webpage