PerCP/Cyanine5.5 anti-human CD206 (MMR) | BioLegend 321121 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PerCP/Cyanine5.5 anti-human CD206 (MMR)

catalog :

321121

quantity :

25 tests

price :

176 USD

clonality :

monoclonal

host :

mouse

conjugate :

PerCP/Cy5.5

clone name :

15-2

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:100; loading ...; fig 6f	Liu Y, Wang L, Song Q, Ali M, Crowe W, Kucera G, et al. Intrapleural nano-immunotherapy promotes innate and adaptive immune responses to enhance anti-PD-L1 therapy for malignant pleural effusion. Nat Nanotechnol. 2022;17:206-216 pubmed publisher
flow cytometry; human; loading ...; fig 2a	Haque A, Moriyama M, Kubota K, Ishiguro N, Sakamoto M, Chinju A, et al. CD206+ tumor-associated macrophages promote proliferation and invasion in oral squamous cell carcinoma via EGF production. Sci Rep. 2019;9:14611 pubmed publisher
	Douthwaite H, Arteagabeitia A, Mukhopadhyay S. Differentiation of Human Induced Pluripotent Stem Cell into Macrophages. Bio Protoc. 2022;12:e4361 pubmed publisher
	Mulder K, Patel A, Kong W, Piot C, Halitzki E, Dunsmore G, et al. Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease. Immunity. 2021;54:1883-1900.e5 pubmed publisher
	Vierboom M, Dijkman K, Sombroek C, Hofman S, Boot C, Vervenne R, et al. Stronger induction of trained immunity by mucosal BCG or MTBVAC vaccination compared to standard intradermal vaccination. Cell Rep Med. 2021;2:100185 pubmed publisher
	Leach S, Gibbings S, Tewari A, Atif S, Vestal B, Danhorn T, et al. Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes. Cell Rep. 2020;33:108337 pubmed publisher
	Wu X, Hollingshead N, Roberto J, Knupp A, Kenerson H, Chen A, et al. Human Liver Macrophage Subsets Defined by CD32. Front Immunol. 2020;11:2108 pubmed publisher
	Ray S, Baban B, Tucker M, Seaton A, Chang K, Mannon E, et al. Oral NaHCO3 Activates a Splenic Anti-Inflammatory Pathway: Evidence That Cholinergic Signals Are Transmitted via Mesothelial Cells. J Immunol. 2018;200:3568-3586 pubmed publisher
	Zhao L, Wang W, Huang S, Yang Z, Xu L, Yang Q, et al. The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts. Genome Biol. 2018;19:35 pubmed publisher
	Hartwig T, Montinaro A, von Karstedt S, Sevko A, Surinova S, Chakravarthy A, et al. The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2. Mol Cell. 2017;65:730-742.e5 pubmed publisher
	Li C, Luo X, Lin Y, Tang X, Ling L, Wang L, et al. A Higher Frequency of CD14+ CD169+ Monocytes/Macrophages in Patients with Colorectal Cancer. PLoS ONE. 2015;10:e0141817 pubmed publisher

product information

Antigen :

CD206

Apps. Abbrev. :

Cat # :

321121

Clone :

15-2

Item :

PerCP/Cyanine5.5 anti-human CD206 (MMR)

Isotype :

Mouse IgG1, κ

Other Names :

MMR (macrophage mannose receptor), MR (mannose receptor), CD206, MRC1

Size :

25 tests

Price (USD) :

176 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PERCP_CYANINE5.5

Immunogen :

Purified human mannose receptor

Application Notes :

The 15-2 antibody blocks the interaction of MMR with its ligand, and inhibits mannose receptor-mediated degradation of t-PA by macrophages. Additional reported applications of this antibody (for the relevant formats) include: Western blotting^1, blocking of ligand binding^1,2, immunofluorescence^3, and immunohistochemical staining of acetone-fixed frozen tissue sections^1. The Utra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 321149 and 321150).;

more info or order :

BioLegend product webpage