APC/Cyanine7 anti-human CD206 (MMR) | BioLegend 321119 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Cyanine7 anti-human CD206 (MMR)

catalog :

321119

quantity :

25 tests

price :

141 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC/Cy7

clone name :

15-2

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 4a	Machacek C, Supper V, Leksa V, Mitulovic G, Spittler A, Drbal K, et al. Folate Receptor ? Regulates Integrin CD11b/CD18 Adhesion of a Macrophage Subset to Collagen. J Immunol. 2016;197:2229-38 pubmed publisher
	Tu J, Tan X, Chen Y, Li Z, Zhang Y, Chen X, et al. Growth arrest-specific transcript 5 represses endometrial cancer development by promoting antitumor function of tumor-associated macrophages. Cancer Sci. 2022;113:2496-2512 pubmed publisher
	Muir L, Cho K, Geletka L, Baker N, Flesher C, Ehlers A, et al. Human CD206+ macrophages associate with diabetes and adipose tissue lymphoid clusters. JCI Insight. 2022;7: pubmed publisher
	Higham A, Baker J, Jackson N, Shah R, Lea S, Singh D. Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients. Cells. 2021;11: pubmed publisher
	van Doorn C, Steenbergen S, Walburg K, Ottenhoff T. Pharmacological Poly (ADP-Ribose) Polymerase Inhibitors Decrease Mycobacterium tuberculosis Survival in Human Macrophages. Front Immunol. 2021;12:712021 pubmed publisher
	Chruewkamlow N, Pruekprasert K, Phutthakunphithak P, Acharayothin O, Prapassaro T, Hongku K, et al. Novel culture media enhances mononuclear cells from patients with chronic limb-threatening ischemia to increase vasculogenesis and anti-inflammatory effect. Stem Cell Res Ther. 2021;12:520 pubmed publisher
	Sabree S, Voigt A, Blackwell S, Vishwakarma A, Chimenti M, Salem A, et al. Direct and indirect immune effects of CMP-001, a virus-like particle containing a TLR9 agonist. J Immunother Cancer. 2021;9: pubmed publisher
	Mehta A, Cheney E, Hartl C, Pantelidou C, Oliwa M, Castrillon J, et al. Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer. Nat Cancer. 2021;2:66-82 pubmed publisher
	Nam J, Son S, Park K, Moon J. Modularly Programmable Nanoparticle Vaccine Based on Polyethyleneimine for Personalized Cancer Immunotherapy. Adv Sci (Weinh). 2021;8:2002577 pubmed publisher
	Tamo L, Fytianos K, Caldana F, Simillion C, Feki A, Nita I, et al. Interactome Analysis of iPSC Secretome and Its Effect on Macrophages In Vitro. Int J Mol Sci. 2021;22: pubmed publisher
	Smith A, Watkins T, Theocharidis G, Lang I, Leschinsky M, Maione A, et al. A Novel Three-Dimensional Skin Disease Model to Assess Macrophage Function in Diabetes. Tissue Eng Part C Methods. 2021;27:49-58 pubmed publisher
	Zhang S, Shrestha C, Wisniewski B, Pham H, Hou X, Li W, et al. Consequences of CRISPR-Cas9-Mediated CFTR Knockout in Human Macrophages. Front Immunol. 2020;11:1871 pubmed publisher
	Bennstein S, Weinhold S, Manser A, Scherenschlich N, Noll A, Raba K, et al. Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells. elife. 2020;9: pubmed publisher
	Nikonova A, Khaitov M, Jackson D, Traub S, Trujillo Torralbo M, Kudlay D, et al. M1-like macrophages are potent producers of anti-viral interferons and M1-associated marker-positive lung macrophages are decreased during rhinovirus-induced asthma exacerbations. EBioMedicine. 2020;54:102734 pubmed publisher
	Castellaro A, Rodriguez Baili M, Di Tada C, Gil G. Tumor-Associated Macrophages Induce Endocrine Therapy Resistance in ER+ Breast Cancer Cells. Cancers (Basel). 2019;11: pubmed publisher
	Cornwell W, Kim V, Fan X, Vega M, Ramsey F, Criner G, et al. Activation and polarization of circulating monocytes in severe chronic obstructive pulmonary disease. BMC Pulm Med. 2018;18:101 pubmed publisher
	Martins A, Narayanan M, Prustel T, Fixsen B, Park K, Gottschalk R, et al. Environment Tunes Propagation of Cell-to-Cell Variation in the Human Macrophage Gene Network. Cell Syst. 2017;4:379-392.e12 pubmed publisher
	Norton S, Dunn E, McCall J, Munro F, Kemp R. Gut macrophage phenotype is dependent on the tumor microenvironment in colorectal cancer. Clin Transl Immunology. 2016;5:e76 pubmed publisher
	Cai Y, Sugimoto C, Arainga M, Midkiff C, Liu D, Alvarez X, et al. Preferential Destruction of Interstitial Macrophages over Alveolar Macrophages as a Cause of Pulmonary Disease in Simian Immunodeficiency Virus-Infected Rhesus Macaques. J Immunol. 2015;195:4884-91 pubmed publisher
	Isik G, van Montfort T, Boot M, Cobos Jiménez V, Kootstra N, Sanders R. Chimeric HIV-1 envelope glycoproteins with potent intrinsic granulocyte-macrophage colony-stimulating factor (GM-CSF) activity. PLoS ONE. 2013;8:e60126 pubmed publisher

product information

Antigen :

CD206

Apps. Abbrev. :

Cat # :

321119

Clone :

15-2

Item :

APC/Cyanine7 anti-human CD206 (MMR)

Isotype :

Mouse IgG1, κ

Other Names :

MMR (macrophage mannose receptor), MR (mannose receptor), CD206, MRC1

Size :

25 tests

Price (USD) :

141 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC_CYANINE7

Immunogen :

Purified human mannose receptor

Application Notes :

The 15-2 antibody blocks the interaction of MMR with its ligand, and inhibits mannose receptor-mediated degradation of t-PA by macrophages. Additional reported applications of this antibody (for the relevant formats) include: Western blotting^1, blocking of ligand binding^1,2, immunofluorescence^3, and immunohistochemical staining of acetone-fixed frozen tissue sections^1. The Utra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 321149 and 321150).;

more info or order :

BioLegend product webpage