PE/Cyanine5 anti-human CD206 (MMR) | BioLegend 321108 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Cyanine5 anti-human CD206 (MMR)

catalog :

321108

quantity :

100 tests

price :

305 USD

clonality :

monoclonal

host :

mouse

conjugate :

PE-Cy5

clone name :

15-2

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:50; loading ...; fig s6a	Frank A, Ebersberger S, Fink A, Lampe S, Weigert A, Schmid T, et al. Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype. Nat Commun. 2019;10:1135 pubmed publisher
	Camiolo M, Zhou X, Oriss T, Yan Q, Gorry M, Horne W, et al. High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status. Cell Rep. 2021;35:108974 pubmed publisher
	Bourdely P, Anselmi G, Vaivode K, Ramos R, Missolo Koussou Y, Hidalgo S, et al. Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells. Immunity. 2020;53:335-352.e8 pubmed publisher
	Weisberg S, Carpenter D, Chait M, Dogra P, Gartrell Corrado R, Chen A, et al. Tissue-Resident Memory T Cells Mediate Immune Homeostasis in the Human Pancreas through the PD-1/PD-L1 Pathway. Cell Rep. 2019;29:3916-3932.e5 pubmed publisher
	Mertens C, Mora J, Oren B, Grein S, Winslow S, Scholich K, et al. Macrophage-derived lipocalin-2 transports iron in the tumor microenvironment. Oncoimmunology. 2018;7:e1408751 pubmed publisher
	Mertens C, Akam E, Rehwald C, Brüne B, Tomat E, Jung M. Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression. PLoS ONE. 2016;11:e0166164 pubmed publisher
	MartÃnez Cingolani C, Grandclaudon M, Jeanmougin M, Jouve M, Zollinger R, Soumelis V. Human blood BDCA-1 dendritic cells differentiate into Langerhans-like cells with thymic stromal lymphopoietin and TGF-Î². Blood. 2014;124:2411-20 pubmed publisher

product information

Antigen :

CD206

Apps. Abbrev. :

Cat # :

321108

Clone :

15-2

Item :

PE/Cyanine5 anti-human CD206 (MMR)

Isotype :

Mouse IgG1, κ

Other Names :

MMR (macrophage mannose receptor), MR (mannose receptor), CD206, MRC1

Size :

100 tests

Price (USD) :

305 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PE_CYANINE5

Immunogen :

Purified human mannose receptor

Application Notes :

The 15-2 antibody blocks the interaction of MMR with its ligand, and inhibits mannose receptor-mediated degradation of t-PA by macrophages. Additional reported applications of this antibody (for the relevant formats) include: Western blotting^1, blocking of ligand binding^1,2, immunofluorescence^3, and immunohistochemical staining of acetone-fixed frozen tissue sections^1. The Utra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 321149 and 321150).;

more info or order :

BioLegend product webpage