product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-human CD206 (MMR)
catalog :
321103
quantity :
25 tests
price :
106 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
15-2
reactivity :
human, mouse
application :
flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 29
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 3h
Tyagi A, Sharma S, Wu K, Wu S, Xing F, Liu Y, et al. Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung. Nat Commun. 2021;12:474 pubmed publisher
Rodriguez Perdigon M, Haeni L, Rothen Rutishauser B, R xfc egg C. Dual CSF1R inhibition and CD40 activation demonstrates anti-tumor activity in a 3D macrophage- HER2+ breast cancer spheroid model. Front Bioeng Biotechnol. 2023;11:1159819 pubmed publisher
Lin H, Fu L, Li P, Zhu J, Xu Q, Wang Y, et al. Fatty acids metabolism affects the therapeutic effect of anti-PD-1/PD-L1 in tumor immune microenvironment in clear cell renal cell carcinoma. J Transl Med. 2023;21:343 pubmed publisher
Chen S, Lu K, Hou Y, You Z, Shu C, Wei X, et al. YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6. J Immunother Cancer. 2023;11: pubmed publisher
Chung J, Tang P, Chan M, Xue V, Huang X, Ng C, et al. Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma. Nat Commun. 2023;14:1794 pubmed publisher
Gelsomino L, Barone I, Caruso A, Giordano F, Brindisi M, Morello G, et al. Proteomic Profiling of Extracellular Vesicles Released by Leptin-Treated Breast Cancer Cells: A Potential Role in Cancer Metabolism. Int J Mol Sci. 2022;23: pubmed publisher
Xu G, Niu L, Wang Y, Yang G, Zhu X, Yao Y, et al. HDAC6-dependent deacetylation of TAK1 enhances sIL-6R release to promote macrophage M2 polarization in colon cancer. Cell Death Dis. 2022;13:888 pubmed publisher
Ronaghan N, Soo M, Pena U, Tellis M, Duan W, Tabatabaei Zavareh N, et al. M1-like, but not M0- or M2-like, macrophages, reduce RSV infection of primary bronchial epithelial cells in a media-dependent fashion. PLoS ONE. 2022;17:e0276013 pubmed publisher
Nyazika T, Sibale L, Phiri J, De Ste Croix M, Jasiunaite Z, Mkandawire C, et al. Intracellular survival of Streptococcus pneumoniae in human alveolar macrophages is augmented with HIV infection. Front Immunol. 2022;13:992659 pubmed publisher
Teng Y, Zou M, Liu S, Jia Y, Zhang K, Yuan Z, et al. Dual-Action Icariin-Containing Thermosensitive Hydrogel for Wound Macrophage Polarization and Hair-Follicle Neogenesis. Front Bioeng Biotechnol. 2022;10:902894 pubmed publisher
Wu J, Sun Z, Liu S, Chen Z, Yuan Z, Zou M, et al. The ASIC3-M-CSF-M2 macrophage-positive feedback loop modulates fibroblast-to-myofibroblast differentiation in skin fibrosis pathogenesis. Cell Death Dis. 2022;13:527 pubmed publisher
Rodriguez Perdigon M, Jimaja S, Haeni L, Bruns N, Rothen Rutishauser B, R xfc egg C. Polymersomes-Mediated Delivery of CSF1R Inhibitor to Tumor Associated Macrophages Promotes M2 to M1-Like Macrophage Repolarization. Macromol Biosci. 2022;22:e2200168 pubmed publisher
Ma C, He D, Tian P, Wang Y, He Y, Wu Q, et al. miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher
Feuerer N, Marzi J, Brauchle E, Carvajal Berrio D, Billing F, Weiss M, et al. Lipidome profiling with Raman microspectroscopy identifies macrophage response to surface topographies of implant materials. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Conforti A, Wahlers T, Paunel Görgülü A. Neutrophil extracellular traps modulate inflammatory markers and uptake of oxidized LDL by human and murine macrophages. PLoS ONE. 2021;16:e0259894 pubmed publisher
Yoshimori M, Nishio M, Ohashi A, Tateishi M, Mimura A, Wada N, et al. Interferon-γ Produced by EBV-Positive Neoplastic NK-Cells Induces Differentiation into Macrophages and Procoagulant Activity of Monocytes, Which Leads to HLH. Cancers (Basel). 2021;13: pubmed publisher
Winkler C, King M, Berthe J, Ferraioli D, Garuti A, Grillo F, et al. SLFN11 captures cancer-immunity interactions associated with platinum sensitivity in high-grade serous ovarian cancer. JCI Insight. 2021;6: pubmed publisher
Dai X, Heng B, Bai Y, You F, Sun X, Li Y, et al. Restoration of electrical microenvironment enhances bone regeneration under diabetic conditions by modulating macrophage polarization. Bioact Mater. 2021;6:2029-2038 pubmed publisher
Argüello R, Combes A, Char R, Gigan J, Baaziz A, Bousiquot E, et al. SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution. Cell Metab. 2020;32:1063-1075.e7 pubmed publisher
Kim S, Saeidi S, Zhong X, Gwak S, Muna I, Park S, et al. Breast cancer cell debris diminishes therapeutic efficacy through heme oxygenase-1-mediated inactivation of M1-like tumor-associated macrophages. Neoplasia. 2020;22:606-616 pubmed publisher
Mansouri S, Katikaneni D, Gogoi H, Pipkin M, Machuca T, Emtiazjoo A, et al. Lung IFNAR1hi TNFR2+ cDC2 promotes lung regulatory T cells induction and maintains lung mucosal tolerance at steady state. Mucosal Immunol. 2020;13:595-608 pubmed publisher
Aung A, Kumar V, Theprungsirikul J, Davey S, Varghese S. An Engineered Tumor-on-a-Chip Device with Breast Cancer-Immune Cell Interactions for Assessing T-cell Recruitment. Cancer Res. 2020;80:263-275 pubmed publisher
Krakow S, Crescimone M, Bartels C, Wiegering V, Eyrich M, Schlegel P, et al. Re-expression of CD14 in Response to a Combined IL-10/TLR Stimulus Defines Monocyte-Derived Cells With an Immunoregulatory Phenotype. Front Immunol. 2019;10:1484 pubmed publisher
Shen M, Chen Y, Xu L, Zhu R, Xue X, Tsai Y, et al. Increased infiltration of macrophages to radioresistant lung cancer cells contributes to the development of the additional resistance of tumor cells to the cytotoxic effects of NK cells. Int J Oncol. 2018;53:317-328 pubmed publisher
Mifuji K, Ishikawa M, Kamei N, Tanaka R, Arita K, Mizuno H, et al. Angiogenic conditioning of peripheral blood mononuclear cells promotes fracture healing. Bone Joint Res. 2017;6:489-498 pubmed publisher
Ball M, Shipman E, Kim H, Liby K, Pioli P. CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages. PLoS ONE. 2016;11:e0149600 pubmed publisher
Herter S, Herting F, Mundigl O, Waldhauer I, Weinzierl T, Fauti T, et al. Preclinical activity of the type II CD20 antibody GA101 (obinutuzumab) compared with rituximab and ofatumumab in vitro and in xenograft models. Mol Cancer Ther. 2013;12:2031-42 pubmed publisher
Zhang Q, Atsuta I, Liu S, Chen C, Shi S, Shi S, et al. IL-17-mediated M1/M2 macrophage alteration contributes to pathogenesis of bisphosphonate-related osteonecrosis of the jaws. Clin Cancer Res. 2013;19:3176-88 pubmed publisher
Dalli J, Serhan C. Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators. Blood. 2012;120:e60-72 pubmed publisher
product information
Antigen :
CD206
Apps. Abbrev. :
FC
Cat # :
321103
Clone :
15-2
Item :
FITC anti-human CD206 (MMR)
Isotype :
Mouse IgG1, κ
Other Names :
MMR (macrophage mannose receptor), MR (mannose receptor), CD206, MRC1
Size :
25 tests
Price (USD) :
106 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
FITC
Immunogen :
Purified human mannose receptor
Application Notes :
The 15-2 antibody blocks the interaction of MMR with its ligand, and inhibits mannose receptor-mediated degradation of t-PA by macrophages. Additional reported applications of this antibody (for the relevant formats) include: Western blotting^1, blocking of ligand binding^1,2, immunofluorescence^3, and immunohistochemical staining of acetone-fixed frozen tissue sections^1. The Utra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 321149 and 321150).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA