APC anti-human MICA/MICB | BioLegend 320907 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human MICA/MICB

catalog :

320907

quantity :

25 tests

price :

149 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

6D4

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 11

Reference
Gerace D, Zhou Q, Kenty J, Veres A, Sintov E, Wang X, et al. Engineering human stem cell-derived islets to evade immune rejection and promote localized immune tolerance. Cell Rep Med. 2023;4:100879 pubmed publisher
Tran T, Kim Y, Duong T, Thangaraj J, Chu T, Jung S, et al. Natural killer cell therapy potentially enhances the antitumor effects of bevacizumab plus irinotecan in a glioblastoma mouse model. Front Immunol. 2022;13:1009484 pubmed publisher
Wu X, Sharma A, Oldenburg J, Weiher H, Essler M, Skowasch D, et al. NKG2D Engagement Alone Is Sufficient to Activate Cytokine-Induced Killer Cells While 2B4 Only Provides Limited Coactivation. Front Immunol. 2021;12:731767 pubmed publisher
Wu J, Chen Z, Wickström S, Gao J, He X, Jing X, et al. Interleukin-33 is a Novel Immunosuppressor that Protects Cancer Cells from TIL Killing by a Macrophage-Mediated Shedding Mechanism. Adv Sci (Weinh). 2021;8:e2101029 pubmed publisher
Martínez Sánchez M, Fuster J, Campillo J, Galera A, Bermúdez Cortés M, Llinares M, et al. Expression of NK Cell Receptor Ligands on Leukemic Cells Is Associated with the Outcome of Childhood Acute Leukemia. Cancers (Basel). 2021;13: pubmed publisher
Ng W, Gong C, Yan X, Si G, Fang C, Wang L, et al. Targeting CD155 by rediocide-A overcomes tumour immuno-resistance to natural killer cells. Pharm Biol. 2021;59:47-53 pubmed publisher
Wu X, Zhang Y, Li Y, Schmidt Wolf I. Increase of Antitumoral Effects of Cytokine-Induced Killer Cells by Antibody-Mediated Inhibition of MICA Shedding. Cancers (Basel). 2020;12: pubmed publisher
Yao C, Ni Z, Gong C, Zhu X, Wang L, Xu Z, et al. Rocaglamide enhances NK cell-mediated killing of non-small cell lung cancer cells by inhibiting autophagy. Autophagy. 2018;14:1831-1844 pubmed publisher
Thomas M, Nyanhete T, Tuero I, Venzon D, Robert Guroff M. Beyond Oncolytics: E1B55K-Deleted Adenovirus as a Vaccine Delivery Vector. PLoS ONE. 2016;11:e0158505 pubmed publisher
Mo C, Dai Y, Kang N, Cui L, He W. Ectopic expression of human MutS homologue 2 on renal carcinoma cells is induced by oxidative stress with interleukin-18 promotion via p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal kinase (JNK) signaling pathways. J Biol Chem. 2012;287:19242-54 pubmed publisher
Okita R, Mougiakakos D, Ando T, Mao Y, Sarhan D, Wennerberg E, et al. HER2/HER3 signaling regulates NK cell-mediated cytotoxicity via MHC class I chain-related molecule A and B expression in human breast cancer cell lines. J Immunol. 2012;188:2136-45 pubmed publisher

product information

Antigen :

MICA MICB

Apps. Abbrev. :

Cat # :

320907

Clone :

6D4

Item :

APC anti-human MICA/MICB

Isotype :

Mouse IgG2a, κ

Other Names :

PERB11, MIC, MHC class I chain-related protein A, MICA, PERB11.1, MHC class I chain-related protein B, MICB, PERB11.2

Size :

25 tests

Price (USD) :

149 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC

Application Notes :

Additional reported (for the relevant formats) applications include: immunohistochemistry^2,3,5 of acetone-fixed frozen sections and formalin-fixed paraffin-embedded tissue sections, immunoprecipitation^7, and blocking^2,3 of MIC mediated cytotoxicity. The Ultra-LEAF™ Purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 320919 & 320120).;

more info or order :

BioLegend product webpage