Ultra-LEAF™ Purified anti-human CD314 (NKG2D) | BioLegend 320813 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Ultra-LEAF™ Purified anti-human CD314 (NKG2D)

catalog :

320813

quantity :

100 μg

price :

182 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1D11

reactivity :

human

application :

immunoprecipitation, flow cytometry

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 4a	Meckiff B, Ladell K, McLaren J, Ryan G, Leese A, James E, et al. Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells. J Immunol. 2019;203:1276-1287 pubmed publisher
flow cytometry; human; loading ...; fig 2a	Ingegnere T, Mariotti F, Pelosi A, Quintarelli C, De Angelis B, Tumino N, et al. Human CAR NK Cells: A New Non-viral Method Allowing High Efficient Transfection and Strong Tumor Cell Killing. Front Immunol. 2019;10:957 pubmed publisher
	Höfle J, Trenkner T, Kleist N, Schwane V, Vollmers S, Barcelona B, et al. Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells. EMBO Rep. 2022;:e54133 pubmed publisher
	Van der Meer J, de Jonge P, van der Waart A, Geerlings A, Moonen J, Brummelman J, et al. CD34+ progenitor-derived NK cell and gemcitabine combination therapy increases killing of ovarian cancer cells in NOD/SCID/IL2Rgnull mice. Oncoimmunology. 2021;10:1981049 pubmed publisher
	Dudek M, Pfister D, Donakonda S, Filpe P, Schneider A, Laschinger M, et al. Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH. Nature. 2021;592:444-449 pubmed publisher
	Thrash E, Kleinsteuber K, Hathaway E, Nazzaro M, Haas E, Hodi F, et al. High-Throughput Mass Cytometry Staining for Immunophenotyping Clinical Samples. STAR Protoc. 2020;1:100055 pubmed publisher
	Breman E, Demoulin B, Agaugué S, Mauen S, Michaux A, Springuel L, et al. Overcoming Target Driven Fratricide for T Cell Therapy. Front Immunol. 2018;9:2940 pubmed publisher
	Glasner A, Isaacson B, Mandelboim O. Expression and function of NKp46 W32R: the human homologous protein of mouse NKp46 W32R (Noé). Sci Rep. 2017;7:40944 pubmed publisher

product information

Antigen :

CD314

Apps. Abbrev. :

FC, IP, FA

Cat # :

320813

Clone :

1D11

Item :

Ultra-LEAF™ Purified anti-human CD314 (NKG2D)

Isotype :

Mouse IgG1, κ

Other Names :

NKG2D

Size :

100 μg

Price (USD) :

182 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

ULEAF

Application Notes :

The 1D11 antibody blocks MICA binding to T cells, induces redirected lysis, and costimulates T cells activation and proliferation. Additional reported (for the relevant formats) applications include: immunoprecipitation^1,2, blocking of ligand binding, induction of redirected cell lysis, and costimulation of T cells proliferation^2-7. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 320814) with endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered.;

more info or order :

BioLegend product webpage