product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-human CD314 (NKG2D)
catalog :
320807
quantity :
25 tests
price :
139 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
1D11
reactivity :
human
application :
flow cytometry
more info or order :
citations: 22
Reference
Stitzlein L, Gangadharan A, Walsh L, Nam D, Espejo A, Singh M, et al. Comparison of pharmacological inhibitors of lysine-specific demethylase 1 in glioblastoma stem cells reveals inhibitor-specific efficacy profiles. Front Neurol. 2023;14:1112207 pubmed publisher
Wang S, Zhang X, Zou X, Wen M, Gan C, Jiang X, et al. Expansion of KRAS hotspot mutations reactive T cells from human pancreatic tumors using autologous T cells as the antigen-presenting cells. Cancer Immunol Immunother. 2023;72:1301-1313 pubmed publisher
Jeon S, Han A, Choi Y, Lee A, Lee J. Lymphoid Lineage γδ T Cells Were Successfully Generated from Human Pluripotent Stem Cells via Hemogenic Endothelium. Int J Stem Cells. 2023;16:108-116 pubmed publisher
Wang M, Wei Y, Li Y, Li H, Jin J, Lu Y, et al. Targeting breast cancer with a combination of DNT and LAG3 checkpoint blockage and its mechanism. Immun Inflamm Dis. 2022;10:e626 pubmed publisher
Welsh J, Killingsworth B, Kepley J, Traynor T, Cook S, Savage J, et al. MPAPASS software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays. Cell Rep Methods. 2022;2:100136 pubmed publisher
Oyer J, Croom Perez T, Dieffenthaller T, Robles Carillo L, Gitto S, Altomare D, et al. Cryopreserved PM21-Particle-Expanded Natural Killer Cells Maintain Cytotoxicity and Effector Functions In Vitro and In Vivo. Front Immunol. 2022;13:861681 pubmed publisher
Wang H, Cao K, Liu S, Xu Y, Tang L. Tim-3 Expression Causes NK Cell Dysfunction in Type 2 Diabetes Patients. Front Immunol. 2022;13:852436 pubmed publisher
Chen M, Li Y, Wu Y, Xie S, Ma J, Yue J, et al. Anti-Tumor Activity of Expanded PBMC-Derived NK Cells by Feeder-Free Protocol in Ovarian Cancer. Cancers (Basel). 2021;13: pubmed publisher
Wu X, Sharma A, Oldenburg J, Weiher H, Essler M, Skowasch D, et al. NKG2D Engagement Alone Is Sufficient to Activate Cytokine-Induced Killer Cells While 2B4 Only Provides Limited Coactivation. Front Immunol. 2021;12:731767 pubmed publisher
Gao Y, Lin H, Guo D, Cheng S, Zhou Y, Zhang L, et al. Suppression of 4.1R enhances the potency of NKG2D-CAR T cells against pancreatic carcinoma via activating ERK signaling pathway. Oncogenesis. 2021;10:62 pubmed publisher
Wu J, Chen Z, Wickström S, Gao J, He X, Jing X, et al. Interleukin-33 is a Novel Immunosuppressor that Protects Cancer Cells from TIL Killing by a Macrophage-Mediated Shedding Mechanism. Adv Sci (Weinh). 2021;8:e2101029 pubmed publisher
Bonte S, De Munter S, Billiet L, Goetgeluk G, Ingels J, Jansen H, et al. In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality. Oncoimmunology. 2021;10:1954800 pubmed publisher
Wu X, Zhang Y, Li Y, Schmidt Wolf I. Increase of Antitumoral Effects of Cytokine-Induced Killer Cells by Antibody-Mediated Inhibition of MICA Shedding. Cancers (Basel). 2020;12: pubmed publisher
Lu H, Jin L, Huang H, Ha S, Yang H, Chang R, et al. Trophoblast-derived CXCL12 promotes CD56bright CD82- CD29+ NK cell enrichment in the decidua. Am J Reprod Immunol. 2020;83: pubmed publisher
Sun B, Yang D, Dai H, Liu X, Jia R, Cui X, et al. Eradication of Hepatocellular Carcinoma by NKG2D-Based CAR-T Cells. Cancer Immunol Res. 2019;7:1813-1823 pubmed publisher
de Jonge K, Ebering A, Nassiri S, Maby El Hajjami H, Ouertatani Sakouhi H, Baumgaertner P, et al. Circulating CD56bright NK cells inversely correlate with survival of melanoma patients. Sci Rep. 2019;9:4487 pubmed publisher
Pahl J, Koch J, Götz J, Arnold A, Reusch U, Gantke T, et al. CD16A Activation of NK Cells Promotes NK Cell Proliferation and Memory-Like Cytotoxicity against Cancer Cells. Cancer Immunol Res. 2018;6:517-527 pubmed publisher
Alhaj Hussen K, Vu Manh T, Guimiot F, Nelson E, Chabaane E, Delord M, et al. Molecular and Functional Characterization of Lymphoid Progenitor Subsets Reveals a Bipartite Architecture of Human Lymphopoiesis. Immunity. 2017;47:680-696.e8 pubmed publisher
Guo S, Du Y, Liu X. Platelet-derived TGF-β1 mediates the down-modulation of NKG2D expression and may be responsible for impaired natural killer (NK) cytotoxicity in women with endometriosis. Hum Reprod. 2016;31:1462-74 pubmed publisher
Bigler M, Egli S, Hysek C, Hoenger G, Schmied L, Baldin F, et al. Stress-Induced In Vivo Recruitment of Human Cytotoxic Natural Killer Cells Favors Subsets with Distinct Receptor Profiles and Associates with Increased Epinephrine Levels. PLoS ONE. 2015;10:e0145635 pubmed publisher
Watanabe M, Kudo Y, Kawano M, Nakayama M, Nakamura K, Kameda M, et al. NKG2D functions as an activating receptor on natural killer cells in the common marmoset (Callithrix jacchus). Int Immunol. 2014;26:597-606 pubmed publisher
Paidipally P, Periasamy S, Barnes P, Dhiman R, Indramohan M, Griffith D, et al. NKG2D-dependent IL-17 production by human T cells in response to an intracellular pathogen. J Immunol. 2009;183:1940-5 pubmed publisher
product information
Antigen :
CD314
Apps. Abbrev. :
FC
Cat # :
320807
Clone :
1D11
Item :
APC anti-human CD314 (NKG2D)
Isotype :
Mouse IgG1, κ
Other Names :
NKG2D
Size :
25 tests
Price (USD) :
139 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
APC
Application Notes :
The 1D11 antibody blocks MICA binding to T cells, induces redirected lysis, and costimulates T cells activation and proliferation. Additional reported (for the relevant formats) applications include: immunoprecipitation^1,2, blocking of ligand binding, induction of redirected cell lysis, and costimulation of T cells proliferation^2-7. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 320814) with endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA