product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-human FOXP3
catalog :
320213
quantity :
25 tests
price :
165 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF647
clone name :
259D
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 29
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:50; fig 1d
Leclerc M, Voilin E, Gros G, Corgnac S, de Montpreville V, Validire P, et al. Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1. Nat Commun. 2019;10:3345 pubmed publisher
  • flow cytometry; human; loading ...; fig s8c
Wen Z, Jin K, Shen Y, Yang Z, Li Y, Wu B, et al. N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation. Nat Immunol. 2019;20:313-325 pubmed publisher
  • flow cytometry; human; loading ...; fig 5a
Richardson J, Armbruster N, Günter M, Henes J, Autenrieth S. Staphylococcus aureus PSM Peptides Modulate Human Monocyte-Derived Dendritic Cells to Prime Regulatory T Cells. Front Immunol. 2018;9:2603 pubmed publisher
Zhao Q, Ren H, Yang N, Xia X, Chen Q, Zhou D, et al. Bifidobacterium pseudocatenulatum-Mediated Bile Acid Metabolism to Prevent Rheumatoid Arthritis via the Gut-Joint Axis. Nutrients. 2023;15: pubmed publisher
Krammer S, Yang Z, Mitl xe4 nder H, Grund J, Trump S, Mittler S, et al. Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells. Cells. 2022;12: pubmed publisher
VanDyke D, Iglesias M, Tomala J, Young A, Smith J, Perry J, et al. Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection. Cell Rep. 2022;41:111478 pubmed publisher
Yang Zhou J, Werner J, Glehr G, Geissler E, Hutchinson J, Kronenberg K. Identification and Isolation of Type II NKT Cell Subsets in Human Blood and Liver. Front Immunol. 2022;13:898473 pubmed publisher
Ferrer Font L, Small S, Lewer B, Pilkington K, Johnston L, Park L, et al. Panel Optimization for High-Dimensional Immunophenotyping Assays Using Full-Spectrum Flow Cytometry. Curr Protoc. 2021;1:e222 pubmed publisher
Ibrahim O, Basse P, Jiang W, Guru K, Chatta G, Kalinski P. NFκB-Activated COX2/PGE2/EP4 Axis Controls the Magnitude and Selectivity of BCG-Induced Inflammation in Human Bladder Cancer Tissues. Cancers (Basel). 2021;13: pubmed publisher
Szabo P, Dogra P, Gray J, Wells S, Connors T, Weisberg S, et al. Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19. Immunity. 2021;54:797-814.e6 pubmed publisher
Laing A, Lorenc A, Del Molino Del Barrio I, Das A, Fish M, Monin L, et al. A dynamic COVID-19 immune signature includes associations with poor prognosis. Nat Med. 2020;26:1623-1635 pubmed publisher
Woolsey C, Jankeel A, Matassov D, Geisbert J, Agans K, Borisevich V, et al. Immune correlates of postexposure vaccine protection against Marburg virus. Sci Rep. 2020;10:3071 pubmed publisher
Burbano Y, Paz A, Caldon C, Constain J, Gonzáles G, Hernández J, et al. Low Frequency Of Regulatory B-Cells And Increased CD4+ and CD8+ Interferon-γ-producing cells in patients with tropical spastic paraparesis associated with human T-cell lymphotropic virus type. Rev Soc Bras Med Trop. 2019;52:e20190101 pubmed publisher
Santoni de Sio F, Passerini L, Restelli S, Valente M, Pramov A, Maccari M, et al. Role of human forkhead box P3 in early thymic maturation and peripheral T-cell homeostasis. J Allergy Clin Immunol. 2018;142:1909-1921.e9 pubmed publisher
Mackroth M, Abel A, Steeg C, Schulze zur Wiesch J, Jacobs T. Acute Malaria Induces PD1+CTLA4+ Effector T Cells with Cell-Extrinsic Suppressor Function. PLoS Pathog. 2016;12:e1005909 pubmed publisher
Demaret J, Dupont G, Venet F, Friggeri A, Lepape A, Rimmelé T, et al. STAT5 phosphorylation in T cell subsets from septic patients in response to recombinant human interleukin-7: a pilot study. J Leukoc Biol. 2015;97:791-6 pubmed publisher
Dupont G, Demaret J, Venet F, Malergue F, Malcus C, Poitevin Later F, et al. Comparative dose-responses of recombinant human IL-2 and IL-7 on STAT5 phosphorylation in CD4+FOXP3- cells versus regulatory T cells: a whole blood perspective. Cytokine. 2014;69:146-9 pubmed publisher
Vudattu N, Waldron Lynch F, Truman L, Deng S, Preston Hurlburt P, Torres R, et al. Humanized mice as a model for aberrant responses in human T cell immunotherapy. J Immunol. 2014;193:587-96 pubmed publisher
Ferraro A, D Alise A, Raj T, Asinovski N, Phillips R, Ergun A, et al. Interindividual variation in human T regulatory cells. Proc Natl Acad Sci U S A. 2014;111:E1111-20 pubmed publisher
Chen C, Huang D, Yao S, Halliday L, Zeng G, Wang R, et al. IL-2 simultaneously expands Foxp3+ T regulatory and T effector cells and confers resistance to severe tuberculosis (TB): implicative Treg-T effector cooperation in immunity to TB. J Immunol. 2012;188:4278-88 pubmed publisher
Presicce P, Orsborn K, King E, Pratt J, Fichtenbaum C, Chougnet C. Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy. PLoS ONE. 2011;6:e28118 pubmed publisher
Long S, Cerosaletti K, Bollyky P, Tatum M, Shilling H, Zhang S, et al. Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects. Diabetes. 2010;59:407-15 pubmed publisher
Long S, Walker M, Rieck M, James E, Kwok W, Sanda S, et al. Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects. Eur J Immunol. 2009;39:612-20 pubmed publisher
Gong G, Shao L, Wang Y, Chen C, Huang D, Yao S, et al. Phosphoantigen-activated V gamma 2V delta 2 T cells antagonize IL-2-induced CD4+CD25+Foxp3+ T regulatory cells in mycobacterial infection. Blood. 2009;113:837-45 pubmed publisher
Long S, Buckner J. Combination of rapamycin and IL-2 increases de novo induction of human CD4(+)CD25(+)FOXP3(+) T cells. J Autoimmun. 2008;30:293-302 pubmed publisher
Tran D, Ramsey H, Shevach E. Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype. Blood. 2007;110:2983-90 pubmed
Groh V, Smythe K, Dai Z, Spies T. Fas-ligand-mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity. Nat Immunol. 2006;7:755-62 pubmed
Gavin M, Torgerson T, Houston E, deRoos P, Ho W, Stray Pedersen A, et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci U S A. 2006;103:6659-64 pubmed
Yang Z, Novak A, Stenson M, Witzig T, Ansell S. Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma. Blood. 2006;107:3639-46 pubmed
product information
Antigen :
FOXP3
Apps. Abbrev. :
ICFC
Cat # :
320213
Clone :
259D
Item :
Alexa Fluor® 647 anti-human FOXP3
Isotype :
Mouse IgG1, κ
Other Names :
Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2
Size :
25 tests
Price (USD) :
165 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A647
Immunogen :
Full-length FOXP3 protein
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA