product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 488 anti-human FOXP3
catalog :
320112
quantity :
100 tests
price :
370 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
206D
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 37
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 3
Herrera Rios D, Mughal S, Teuber Hanselmann S, Pierscianek D, Sucker A, Jansen P, et al. Macrophages/Microglia Represent the Major Source of Indolamine 2,3-Dioxygenase Expression in Melanoma Metastases of the Brain. Front Immunol. 2020;11:120 pubmed publisher
  • flow cytometry; human; loading ...; fig 1
Ondigo B, Ndombi E, Nicholson S, Oguso J, Carter J, Kittur N, et al. Functional Studies of T Regulatory Lymphocytes in Human Schistosomiasis in Western Kenya. Am J Trop Med Hyg. 2018;98:1770-1781 pubmed publisher
  • flow cytometry; human; loading ...; fig 3b
  • immunohistochemistry; human; loading ...; fig 3a
Amodio D, Cotugno N, Macchiarulo G, Rocca S, Dimopoulos Y, Castrucci M, et al. Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination. J Immunol. 2018;200:538-550 pubmed publisher
  • flow cytometry; human; loading ...; fig 1b
Wei C, Mei J, Tang L, Liu Y, Li D, Li M, et al. 1-Methyl-tryptophan attenuates regulatory T cells differentiation due to the inhibition of estrogen-IDO1-MRC2 axis in endometriosis. Cell Death Dis. 2016;7:e2489 pubmed publisher
Pernaa N, Keskitalo S, Chowdhury I, Nissinen A, Glumoff V, Keski Filppula R, et al. Heterozygous premature termination in zinc-finger domain of Krüppel-like factor 2 gene associates with dysregulated immunity. Front Immunol. 2022;13:819929 pubmed publisher
Riese P, Trittel S, Akmatov M, May M, Prokein J, Illig T, et al. Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly. Nat Commun. 2022;13:6894 pubmed publisher
Alam A, Levanduski E, Denz P, Villavicencio H, Bhatta M, Alhorebi L, et al. Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer. Cancer Cell. 2022;40:153-167.e11 pubmed publisher
Hirschberger S, Strauß G, Effinger D, Marstaller X, Ferstl A, Müller M, et al. Very-low-carbohydrate diet enhances human T-cell immunity through immunometabolic reprogramming. EMBO Mol Med. 2021;13:e14323 pubmed publisher
Delacher M, Simon M, Sanderink L, Hotz Wagenblatt A, Wuttke M, Schambeck K, et al. Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells. Immunity. 2021;54:702-720.e17 pubmed publisher
Wang S, Li M, Sun F, Chen C, Ye J, Li D, et al. Th17/Treg-cell balance in the peripheral blood of pregnant females with a history of recurrent spontaneous abortion receiving progesterone or cyclosporine A. Exp Ther Med. 2021;21:37 pubmed publisher
Faust H, Zhang H, Han J, Wolf M, Jeon O, Sadtler K, et al. IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis. J Clin Invest. 2020;130:5493-5507 pubmed publisher
Husseiny M, Fahmy A, Du W, Gu A, Garcia P, Ferreri K, et al. Development of Quantitative Methylation-Specific Droplet Digital PCR (ddMSP) for Assessment of Natural Tregs. Front Genet. 2020;11:300 pubmed publisher
Woolsey C, Jankeel A, Matassov D, Geisbert J, Agans K, Borisevich V, et al. Immune correlates of postexposure vaccine protection against Marburg virus. Sci Rep. 2020;10:3071 pubmed publisher
Dean J, Peters L, Fuhrman C, Seay H, Posgai A, Stimpson S, et al. Innate inflammation drives NK cell activation to impair Treg activity. J Autoimmun. 2020;108:102417 pubmed publisher
Burbano Y, Paz A, Caldon C, Constain J, Gonzáles G, Hernández J, et al. Low Frequency Of Regulatory B-Cells And Increased CD4+ and CD8+ Interferon-γ-producing cells in patients with tropical spastic paraparesis associated with human T-cell lymphotropic virus type. Rev Soc Bras Med Trop. 2019;52:e20190101 pubmed publisher
Van Gool F, Nguyen M, Mumbach M, Satpathy A, Rosenthal W, Giacometti S, et al. A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells. Immunity. 2019;50:362-377.e6 pubmed publisher
Kubin M, Kokkonen N, Palatsi R, Hägg P, Väyrynen J, Glumoff V, et al. Clinical Efficiency of Topical Calcipotriol/Betamethasone Treatment in Psoriasis Relies on Suppression of the Inflammatory TNF? - IL-23 - IL-17 Axis. Acta Derm Venereol. 2017;97:449-455 pubmed publisher
Fuhrman C, Yeh W, Seay H, Saikumar Lakshmi P, Chopra G, Zhang L, et al. Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226. J Immunol. 2015;195:145-55 pubmed publisher
Zsiros E, Duttagupta P, Dangaj D, Li H, Frank R, Garrabrant T, et al. The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy. Clin Cancer Res. 2015;21:2840-50 pubmed publisher
Jin J, Zhang W, Wong K, Kwak M, van Driel I, Yu Q. Inhibition of breast cancer resistance protein (ABCG2) in human myeloid dendritic cells induces potent tolerogenic functions during LPS stimulation. PLoS ONE. 2014;9:e104753 pubmed publisher
Hodi F, Lawrence D, Lezcano C, Wu X, Zhou J, Sasada T, et al. Bevacizumab plus ipilimumab in patients with metastatic melanoma. Cancer Immunol Res. 2014;2:632-42 pubmed publisher
Nettenstrom L, Alderson K, Raschke E, Evans M, Sondel P, Olek S, et al. An optimized multi-parameter flow cytometry protocol for human T regulatory cell analysis on fresh and viably frozen cells, correlation with epigenetic analysis, and comparison of cord and adult blood. J Immunol Methods. 2013;387:81-8 pubmed publisher
Kelsen J, Bartels L, Dige A, Hvas C, Frings Meuthen P, Boehme G, et al. 21 Days head-down bed rest induces weakening of cell-mediated immunity - Some spaceflight findings confirmed in a ground-based analog. Cytokine. 2012;59:403-9 pubmed publisher
Ryba M, Marek N, Hak Ł, Rybarczyk Kapturska K, Myśliwiec M, Trzonkowski P, et al. Anti-TNF rescue CD4+Foxp3+ regulatory T cells in patients with type 1 diabetes from effects mediated by TNF. Cytokine. 2011;55:353-61 pubmed publisher
Nigam P, Velu V, Kannanganat S, Chennareddi L, Kwa S, Siddiqui M, et al. Expansion of FOXP3+ CD8 T cells with suppressive potential in colorectal mucosa following a pathogenic simian immunodeficiency virus infection correlates with diminished antiviral T cell response and viral control. J Immunol. 2010;184:1690-701 pubmed publisher
Kmieciak M, Gowda M, Graham L, Godder K, Bear H, Marincola F, et al. Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function. J Transl Med. 2009;7:89 pubmed publisher
Nevala W, Vachon C, Leontovich A, Scott C, Thompson M, Markovic S. Evidence of systemic Th2-driven chronic inflammation in patients with metastatic melanoma. Clin Cancer Res. 2009;15:1931-9 pubmed publisher
Raghavan S, Cao D, Widhe M, Roth K, Herrath J, Engstrom M, et al. FOXP3 expression in blood, synovial fluid and synovial tissue during inflammatory arthritis and intra-articular corticosteroid treatment. Ann Rheum Dis. 2009;68:1908-15 pubmed publisher
Grant J, Bourcier K, Wallace S, Pan D, Conway A, Seyfert Margolis V, et al. Validated protocol for FoxP3 reveals increased expression in type 1 diabetes patients. Cytometry B Clin Cytom. 2009;76:69-78 pubmed publisher
Zheng Y, Manzotti C, Burke F, Dussably L, Qureshi O, Walker L, et al. Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3. J Immunol. 2008;181:1683-91 pubmed
Kavanagh B, O Brien S, Lee D, Hou Y, Weinberg V, Rini B, et al. CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion. Blood. 2008;112:1175-83 pubmed publisher
Zonios D, Falloon J, Bennett J, Shaw P, Chaitt D, Baseler M, et al. Idiopathic CD4+ lymphocytopenia: natural history and prognostic factors. Blood. 2008;112:287-94 pubmed publisher
Pillai V, Karandikar N. Attack on the clones? Human FOXP3 detection by PCH101, 236A/E7, 206D, and 259D reveals 259D as the outlier with lower sensitivity. Blood. 2008;111:463-4; author reply 464-6 pubmed
Hartigan O Connor D, Abel K, McCune J. Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression. J Exp Med. 2007;204:2679-92 pubmed
Tran D, Ramsey H, Shevach E. Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype. Blood. 2007;110:2983-90 pubmed
Gao Q, Qiu S, Fan J, Zhou J, Wang X, Xiao Y, et al. Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection. J Clin Oncol. 2007;25:2586-93 pubmed
Liu W, Putnam A, Xu Yu Z, Szot G, Lee M, Zhu S, et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med. 2006;203:1701-11 pubmed
product information
Antigen :
FOXP3
Apps. Abbrev. :
ICFC
Cat # :
320112
Clone :
206D
Item :
Alexa Fluor® 488 anti-human FOXP3
Isotype :
Mouse IgG1, κ
Other Names :
Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2
Size :
100 tests
Price (USD) :
370 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A488
Immunogen :
Full-length FOXP3 protein
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA