product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-mouse/rat/human FOXP3
catalog :
320014
quantity :
100 tests
price :
370 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF647
clone name :
150D
reactivity :
human, mouse, rat, rhesus macaque
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 64
Published Application/Species/Sample/DilutionReference
  • flow cytometry; rat; loading ...; fig 10a
Bath N, Verhoven B, Wilson N, Zeng W, Zhong W, Coons L, et al. APRIL/BLyS deficient rats prevent donor specific antibody (DSA) production and cell proliferation in rodent kidney transplant model. PLoS ONE. 2022;17:e0275564 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5e
Lee A, Pingali S, Pinilla Ibarz J, Atchison M, Koumenis C, Argon Y, et al. Loss of AID exacerbates the malignant progression of CLL. Leukemia. 2022;36:2430-2442 pubmed publisher
  • flow cytometry; mouse; fig 2f
Wu B, Song M, Dong Q, Xiang G, Li J, Ma X, et al. UBR5 promotes tumor immune evasion through enhancing IFN-γ-induced PDL1 transcription in triple negative breast cancer. Theranostics. 2022;12:5086-5102 pubmed publisher
  • flow cytometry; human; loading ...; fig 1c
Pan C, Wu Q, Wang S, Mei Z, Zhang L, Gao X, et al. Combination with Toll-like receptor 4 (TLR4) agonist reverses GITR agonism mediated M2 polarization of macrophage in Hepatocellular carcinoma. Oncoimmunology. 2022;11:2073010 pubmed publisher
  • flow cytometry; mouse; fig 5g
Horiuchi S, Wu H, Liu W, Schmitt N, Provot J, Liu Y, et al. Tox2 is required for the maintenance of GC TFH cells and the generation of memory TFH cells. Sci Adv. 2021;7:eabj1249 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 1a
Amoozgar Z, Kloepper J, Ren J, Tay R, Kazer S, Kiner E, et al. Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas. Nat Commun. 2021;12:2582 pubmed publisher
  • flow cytometry; human; loading ...; fig 4f
Di Blasi D, Boldanova T, Mori L, Terracciano L, Heim M, De Libero G. Unique T-Cell Populations Define Immune-Inflamed Hepatocellular Carcinoma. Cell Mol Gastroenterol Hepatol. 2020;9:195-218 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Cornelissen L, Blanas A, van der Horst J, Kruijssen L, Zaal A, O Toole T, et al. Disruption of sialic acid metabolism drives tumor growth by augmenting CD8+ T cell apoptosis. Int J Cancer. 2019;144:2290-2302 pubmed publisher
  • flow cytometry; rhesus macaque; loading ...; fig 2g
Hoang T, Harper J, Pino M, Wang H, Micci L, King C, et al. Bone Marrow-Derived CD4+ T Cells Are Depleted in Simian Immunodeficiency Virus-Infected Macaques and Contribute to the Size of the Replication-Competent Reservoir. J Virol. 2019;93: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Varelias A, Bunting M, Ormerod K, Koyama M, Olver S, Straube J, et al. Recipient mucosal-associated invariant T cells control GVHD within the colon. J Clin Invest. 2018;128:1919-1936 pubmed publisher
  • flow cytometry; mouse; 1:50; loading ...; fig 5b
Hasan Z, Koizumi S, Sasaki D, Yamada H, Arakaki N, Fujihara Y, et al. JunB is essential for IL-23-dependent pathogenicity of Th17 cells. Nat Commun. 2017;8:15628 pubmed publisher
  • flow cytometry; human
Wang Z, Wei M, Zhang H, Chen H, Germana S, Huang C, et al. Diphtheria-toxin based anti-human CCR4 immunotoxin for targeting human CCR4(+) cells in vivo. Mol Oncol. 2015;9:1458-70 pubmed publisher
  • flow cytometry; mouse; fig 2
Liechtenstein T, Perez Janices N, Blanco Luquin I, Goyvaerts C, Schwarze J, Dufait I, et al. Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy. Oncoimmunology. 2014;3:e945378 pubmed
  • flow cytometry; mouse
Thauland T, Koguchi Y, Dustin M, Parker D. CD28-CD80 interactions control regulatory T cell motility and immunological synapse formation. J Immunol. 2014;193:5894-903 pubmed publisher
Zhao K, Ren C, Tang D, Zhao L, Chen X, Wang Y, et al. The altering cellular components and function in tumor microenvironment during remissive and relapsed stages of anti-CD19 CAR T-cell treated lymphoma mice. Front Immunol. 2023;14:1101769 pubmed publisher
Li Y, Zhang H, Wang R, Wang Y, Li R, Zhu M, et al. Tumor Cell Nanovaccines Based on Genetically Engineered Antibody-Anchored Membrane. Adv Mater. 2023;35:e2208923 pubmed publisher
Ou W, Stewart S, White A, Kwizera E, Xu J, Fang Y, et al. In-situ cryo-immune engineering of tumor microenvironment with cold-responsive nanotechnology for cancer immunotherapy. Nat Commun. 2023;14:392 pubmed publisher
Blomberg O, Spagnuolo L, Garner H, Voorwerk L, Isaeva O, van Dyk E, et al. IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer. Cancer Cell. 2023;41:106-123.e10 pubmed publisher
Yang J, Pei G, Sun X, Xiao Y, Miao C, Zhou L, et al. RhoB affects colitis through modulating cell signaling and intestinal microbiome. Microbiome. 2022;10:149 pubmed publisher
Li Q, Sun X, Yu K, Lv J, Miao C, Yang J, et al. Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance. Cell Rep. 2022;40:111308 pubmed publisher
Zhong W, Lin W, Yang Y, Chen D, Cao X, Xu M, et al. An acquired phosphatidylinositol 4-phosphate transport initiates T-cell deterioration and leukemogenesis. Nat Commun. 2022;13:4390 pubmed publisher
Chan J, Loughland J, de la Parte L, Okano S, Ssewanyana I, Nalubega M, et al. Age-dependent changes in circulating Tfh cells influence development of functional malaria antibodies in children. Nat Commun. 2022;13:4159 pubmed publisher
Liu H, Wu W, Sun G, Chia T, Cao L, Liu X, et al. Optimal target saturation of ligand-blocking anti-GITR antibody IBI37G5 dictates FcγR-independent GITR agonism and antitumor activity. Cell Rep Med. 2022;3:100660 pubmed publisher
Pathania A, Prathipati P, Olwenyi O, Chava S, Smith O, Gupta S, et al. miR-15a and miR-15b modulate natural killer and CD8+T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma. Mol Ther Oncolytics. 2022;25:308-329 pubmed publisher
Wang R, Chen J, Wang W, Zhao Z, Wang H, Liu S, et al. CD40L-armed oncolytic herpes simplex virus suppresses pancreatic ductal adenocarcinoma by facilitating the tumor microenvironment favorable to cytotoxic T cell response in the syngeneic mouse model. J Immunother Cancer. 2022;10: pubmed publisher
Gao R, He B, Huang Q, Wang Z, Yan M, Lam E, et al. Cancer cell immune mimicry delineates onco-immunologic modulation. iScience. 2021;24:103133 pubmed publisher
Chen Y, Wu Q, Wei J, Hu J, Zheng S. Effects of aspirin, vitamin D3, and progesterone on pregnancy outcomes in an autoimmune recurrent spontaneous abortion model. Braz J Med Biol Res. 2021;54:e9570 pubmed publisher
Gonzalez M, Bamidele A, Svingen P, Sagstetter M, Smyrk T, Gaballa J, et al. BMI1 maintains the Treg epigenomic landscape to prevent inflammatory bowel disease. J Clin Invest. 2021;131: pubmed publisher
Prosser A, Huang W, Liu L, Dart S, Watson M, De Boer B, et al. Dynamic changes to tissue-resident immunity after MHC-matched and MHC-mismatched solid organ transplantation. Cell Rep. 2021;35:109141 pubmed publisher
Kato H, Perl A. Double-Edged Sword: Interleukin-2 Promotes T Regulatory Cell Differentiation but Also Expands Interleukin-13- and Interferon-γ-Producing CD8+ T Cells via STAT6-GATA-3 Axis in Systemic Lupus Erythematosus. Front Immunol. 2021;12:635531 pubmed publisher
Rodriguez Garcia A, Lynn R, Poussin M, Eiva M, Shaw L, O Connor R, et al. CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy. Nat Commun. 2021;12:877 pubmed publisher
Kim D, Kim H, Cho S, Yoo S, Kim W, Yeon H, et al. Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells. elife. 2021;10: pubmed publisher
Chen L, Zhang J, Zou Y, Wang F, Li J, Sun F, et al. Kdm2a deficiency in macrophages enhances thermogenesis to protect mice against HFD-induced obesity by enhancing H3K36me2 at the Pparg locus. Cell Death Differ. 2021;28:1880-1899 pubmed publisher
Aqel S, Yang X, Kraus E, Song J, Farinas M, Zhao E, et al. A STAT3 inhibitor ameliorates CNS autoimmunity by restoring Teff:Treg balance. JCI Insight. 2021;6: pubmed publisher
Hoang T, Pino M, Boddapati A, Viox E, Starke C, Upadhyay A, et al. Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques. Cell. 2021;184:460-475.e21 pubmed publisher
Zhang L, Wang W, Wang R, Zhang N, Shang H, Bi Y, et al. Reshaping the Immune Microenvironment by Oncolytic Herpes Simplex Virus in Murine Pancreatic Ductal Adenocarcinoma. Mol Ther. 2021;29:744-761 pubmed publisher
Hoang T, Pino M, Boddapati A, Viox E, Starke C, Upadhyay A, et al. Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques. bioRxiv. 2020;: pubmed publisher
Alissafi T, Kalafati L, Lazari M, Filia A, Kloukina I, Manifava M, et al. Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity. Cell Metab. 2020;32:591-604.e7 pubmed publisher
Toriyama K, Kuwahara M, Kondoh H, Mikawa T, Takemori N, Konishi A, et al. T cell-specific deletion of Pgam1 reveals a critical role for glycolysis in T cell responses. Commun Biol. 2020;3:394 pubmed publisher
Goggi J, Tan Y, Hartimath S, Jieu B, Hwang Y, Jiang L, et al. Granzyme B PET Imaging of Immune Checkpoint Inhibitor Combinations in Colon Cancer Phenotypes. Mol Imaging Biol. 2020;22:1392-1402 pubmed publisher
Abu El Rub E, Sareen N, Yan W, Alagarsamy K, Rafieerad A, Srivastava A, et al. Hypoxia-induced shift in the phenotype of proteasome from 26S toward immunoproteasome triggers loss of immunoprivilege of mesenchymal stem cells. Cell Death Dis. 2020;11:419 pubmed publisher
Liu Y, Tang B, Wang F, Tang L, Lei Y, Luo Y, et al. Parthenolide ameliorates colon inflammation through regulating Treg/Th17 balance in a gut microbiota-dependent manner. Theranostics. 2020;10:5225-5241 pubmed publisher
Harper J, Gordon S, Chan C, Wang H, Lindemuth E, Galardi C, et al. CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption. Nat Med. 2020;26:519-528 pubmed publisher
Lu Y, Zhao Q, Liao J, Song E, Xia Q, Pan J, et al. Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity. Cell. 2020;180:1081-1097.e24 pubmed publisher
He B, Johansson Percival A, Backhouse J, Li J, Lee G, Hamzah J, et al. Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy. Cell Rep. 2020;30:714-724.e5 pubmed publisher
Garo L, Ajay A, Fujiwara M, Beynon V, Kuhn C, Gabriely G, et al. Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity. Cell Rep. 2019;28:3353-3366.e5 pubmed publisher
Chen M, Reed R, Lane A. Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense. Cell Stem Cell. 2019;25:501-513.e5 pubmed publisher
Werbner M, Barsheshet Y, Werbner N, Zigdon M, Averbuch I, Ziv O, et al. Social-Stress-Responsive Microbiota Induces Stimulation of Self-Reactive Effector T Helper Cells. mSystems. 2019;4: pubmed publisher
Jayachandran R, Gumienny A, Bolinger B, Ruehl S, Lang M, Fucile G, et al. Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity. Immunity. 2019;50:152-165.e8 pubmed publisher
Frazier T, Lee S, Bowles A, Semon J, Bunnell B, Wu X, et al. Gender and age-related cell compositional differences in C57BL/6 murine adipose tissue stromal vascular fraction. Adipocyte. 2018;7:183-189 pubmed publisher
Best S, De Souza D, Kersbergen A, Policheni A, Dayalan S, Tull D, et al. Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment. Cell Metab. 2018;27:935-943.e4 pubmed publisher
Ma W, Liu Q, Yang J, Yang Y, Zhao Z, Ma H, et al. A Mouse Model of Autoimmune Cholangitis via Syngeneic Bile Duct Protein Immunization. Sci Rep. 2017;7:15246 pubmed publisher
McGary C, Deléage C, Harper J, Micci L, Ribeiro S, Paganini S, et al. CTLA-4+PD-1- Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques. Immunity. 2017;47:776-788.e5 pubmed publisher
Palacios Arreola M, Nava Castro K, Río Araiza V, Pérez Sánchez N, Morales Montor J. A single neonatal administration of Bisphenol A induces higher tumour weight associated to changes in tumour microenvironment in the adulthood. Sci Rep. 2017;7:10573 pubmed publisher
Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, et al. The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis. Nat Commun. 2014;5:3555 pubmed publisher
Li S, Cai C, Feng J, Li X, Wang Y, Yang J, et al. Peripheral T lymphocyte subset imbalances in children with enterovirus 71-induced hand, foot and mouth disease. Virus Res. 2014;180:84-91 pubmed publisher
Haque A, Stanley A, Amante F, Rivera F, Zhou Y, Kuns R, et al. Therapeutic glucocorticoid-induced TNF receptor-mediated amplification of CD4+ T cell responses enhances antiparasitic immunity. J Immunol. 2010;184:2583-92 pubmed publisher
Klunker S, Chong M, Mantel P, Palomares O, Bassin C, Ziegler M, et al. Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells. J Exp Med. 2009;206:2701-15 pubmed publisher
Fallarino F, Luca G, Calvitti M, Mancuso F, Nastruzzi C, Fioretti M, et al. Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone. J Exp Med. 2009;206:2511-26 pubmed publisher
Golovina T, Mikheeva T, Suhoski M, Aqui N, Tai V, Shan X, et al. CD28 costimulation is essential for human T regulatory expansion and function. J Immunol. 2008;181:2855-68 pubmed
Jordan J, Woods M, Olano J, Walker D. The absence of Toll-like receptor 4 signaling in C3H/HeJ mice predisposes them to overwhelming rickettsial infection and decreased protective Th1 responses. Infect Immun. 2008;76:3717-24 pubmed publisher
Valencia X, Yarboro C, Illei G, Lipsky P. Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus. J Immunol. 2007;178:2579-88 pubmed
Bamias G, Okazawa A, Rivera Nieves J, Arseneau K, De La Rue S, Pizarro T, et al. Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis. J Immunol. 2007;178:1809-18 pubmed
Mayack S, Berg L. Cutting edge: an alternative pathway of CD4+ T cell differentiation is induced following activation in the absence of gamma-chain-dependent cytokine signals. J Immunol. 2006;176:2059-63 pubmed
product information
Antigen :
FOXP3
Apps. Abbrev. :
ICFC
Cat # :
320014
Clone :
150D
Item :
Alexa Fluor® 647 anti-mouse/rat/human FOXP3
Isotype :
Mouse IgG1, κ
Other Names :
Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2
Size :
100 tests
Price (USD) :
370 USD
Reactivity :
Human, Mouse, Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A647
Immunogen :
Full-length FOXP3 protein
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA