product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 488 anti-mouse/rat/human FOXP3
catalog :
320012
quantity :
100 tests
price :
370 USD
clonality :
monoclonal
host :
mouse
conjugate :
AF488
clone name :
150D
reactivity :
human, mouse, rat, rhesus macaque
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 59
Published Application/Species/Sample/DilutionReference
  • flow cytometry; rat; loading ...; fig 10a
Bath N, Verhoven B, Wilson N, Zeng W, Zhong W, Coons L, et al. APRIL/BLyS deficient rats prevent donor specific antibody (DSA) production and cell proliferation in rodent kidney transplant model. PLoS ONE. 2022;17:e0275564 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5e
Lee A, Pingali S, Pinilla Ibarz J, Atchison M, Koumenis C, Argon Y, et al. Loss of AID exacerbates the malignant progression of CLL. Leukemia. 2022;36:2430-2442 pubmed publisher
  • flow cytometry; mouse; fig 2f
Wu B, Song M, Dong Q, Xiang G, Li J, Ma X, et al. UBR5 promotes tumor immune evasion through enhancing IFN-γ-induced PDL1 transcription in triple negative breast cancer. Theranostics. 2022;12:5086-5102 pubmed publisher
  • flow cytometry; human; loading ...; fig 1c
Pan C, Wu Q, Wang S, Mei Z, Zhang L, Gao X, et al. Combination with Toll-like receptor 4 (TLR4) agonist reverses GITR agonism mediated M2 polarization of macrophage in Hepatocellular carcinoma. Oncoimmunology. 2022;11:2073010 pubmed publisher
  • flow cytometry; mouse; fig 5g
Horiuchi S, Wu H, Liu W, Schmitt N, Provot J, Liu Y, et al. Tox2 is required for the maintenance of GC TFH cells and the generation of memory TFH cells. Sci Adv. 2021;7:eabj1249 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 1a
Amoozgar Z, Kloepper J, Ren J, Tay R, Kazer S, Kiner E, et al. Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas. Nat Commun. 2021;12:2582 pubmed publisher
  • flow cytometry; human; 1:100; loading ...; fig 7a
Martínez Fábregas J, Wilmes S, Wang L, Hafer M, Pohler E, Lokau J, et al. Kinetics of cytokine receptor trafficking determine signaling and functional selectivity. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Cornelissen L, Blanas A, van der Horst J, Kruijssen L, Zaal A, O Toole T, et al. Disruption of sialic acid metabolism drives tumor growth by augmenting CD8+ T cell apoptosis. Int J Cancer. 2019;144:2290-2302 pubmed publisher
  • flow cytometry; rhesus macaque; loading ...; fig 2g
Hoang T, Harper J, Pino M, Wang H, Micci L, King C, et al. Bone Marrow-Derived CD4+ T Cells Are Depleted in Simian Immunodeficiency Virus-Infected Macaques and Contribute to the Size of the Replication-Competent Reservoir. J Virol. 2019;93: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2a
Varelias A, Bunting M, Ormerod K, Koyama M, Olver S, Straube J, et al. Recipient mucosal-associated invariant T cells control GVHD within the colon. J Clin Invest. 2018;128:1919-1936 pubmed publisher
  • flow cytometry; mouse; 1:50; loading ...; fig 5b
Hasan Z, Koizumi S, Sasaki D, Yamada H, Arakaki N, Fujihara Y, et al. JunB is essential for IL-23-dependent pathogenicity of Th17 cells. Nat Commun. 2017;8:15628 pubmed publisher
  • flow cytometry; mouse; fig 6
Tagliamonte M, Petrizzo A, Napolitano M, Luciano A, Rea D, Barbieri A, et al. A novel multi-drug metronomic chemotherapy significantly delays tumor growth in mice. J Transl Med. 2016;14:58 pubmed publisher
Zhao Q, Yu J, Zhou H, Wang X, Zhang C, Hu J, et al. Intestinal dysbiosis exacerbates the pathogenesis of psoriasis-like phenotype through changes in fatty acid metabolism. Signal Transduct Target Ther. 2023;8:40 pubmed publisher
Yu J, Zhou B, Zhang S, Yin H, Sun L, Pu Y, et al. Design of a self-driven probiotic-CRISPR/Cas9 nanosystem for sono-immunometabolic cancer therapy. Nat Commun. 2022;13:7903 pubmed publisher
Li Q, Sun X, Yu K, Lv J, Miao C, Yang J, et al. Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance. Cell Rep. 2022;40:111308 pubmed publisher
Liu B, Mao Z, Yin N, Gu Q, Qi Y, Li X, et al. MW‑9, a chalcones derivative bearing heterocyclic moieties, attenuates experimental autoimmune encephalomyelitis via suppressing pathogenic TH17 cells. Mol Med Rep. 2022;26: pubmed publisher
Du J, Wang Q, Yang S, Chen S, Fu Y, Spath S, et al. FOXP3 exon 2 controls Treg stability and autoimmunity. Sci Immunol. 2022;7:eabo5407 pubmed publisher
Campisi L, Chizari S, Ho J, Gromova A, Arnold F, Mosca L, et al. Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4. Nature. 2022;606:945-952 pubmed publisher
Anderson A, Wu I, Parrillo A, Wolf M, Maestas D, Graham I, et al. An immunologically active, adipose-derived extracellular matrix biomaterial for soft tissue reconstruction: concept to clinical trial. NPJ Regen Med. 2022;7:6 pubmed publisher
Chaurio R, Anadon C, Lee Costich T, Payne K, Biswas S, Harro C, et al. TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures. Immunity. 2022;55:115-128.e9 pubmed publisher
An J, Ding Y, Yu C, Li J, You S, Liu Z, et al. AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells. iScience. 2022;25:103570 pubmed publisher
Shi R, Zhao K, Wang T, Yuan J, Zhang D, Xiang W, et al. 5-aza-2'-deoxycytidine potentiates anti-tumor immunity in colorectal peritoneal metastasis by modulating ABC A9-mediated cholesterol accumulation in macrophages. Theranostics. 2022;12:875-890 pubmed publisher
Machhi J, Yeapuri P, Lu Y, Foster E, Chikhale R, Herskovitz J, et al. CD4+ effector T cells accelerate Alzheimer's disease in mice. J Neuroinflammation. 2021;18:272 pubmed publisher
Nakazawa Y, Nishiyama N, Koizumi H, Kanemaru K, Nakahashi Oda C, Shibuya A. Tumor-derived extracellular vesicles regulate tumor-infiltrating regulatory T cells via the inhibitory immunoreceptor CD300a. elife. 2021;10: pubmed publisher
Schmitz T, Hoffmann V, Olliges E, Bobinger A, Popovici R, Nößner E, et al. Reduced frequency of perforin-positive CD8+ T cells in menstrual effluent of endometriosis patients. J Reprod Immunol. 2021;148:103424 pubmed publisher
Gkountidi A, Garnier L, Dubrot J, Angelillo J, Harl xe9 G, Brighouse D, et al. MHC Class II Antigen Presentation by Lymphatic Endothelial Cells in Tumors Promotes Intratumoral Regulatory T cell-Suppressive Functions. Cancer Immunol Res. 2021;9:748-764 pubmed publisher
Schiller M, Azulay Debby H, Boshnak N, Elyahu Y, Korin B, Ben Shaanan T, et al. Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation. Immunity. 2021;54:1022-1036.e8 pubmed publisher
Nesterenko P, McLaughlin J, Cheng D, Bangayan N, Burton Sojo G, Seet C, et al. Droplet-based mRNA sequencing of fixed and permeabilized cells by CLInt-seq allows for antigen-specific TCR cloning. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Wang N, Yi H, Fang L, Jin J, Ma Q, Shen Y, et al. CD226 Attenuates Treg Proliferation via Akt and Erk Signaling in an EAE Model. Front Immunol. 2020;11:1883 pubmed publisher
Mirando A, Patil A, Rafie C, Christmas B, Pandey N, Stearns V, et al. Regulation of the tumor immune microenvironment and vascular normalization in TNBC murine models by a novel peptide. Oncoimmunology. 2020;9:1760685 pubmed publisher
Renga G, Bellet M, Pariano M, Gargaro M, Stincardini C, D Onofrio F, et al. Thymosin α1 protects from CTLA-4 intestinal immunopathology. Life Sci Alliance. 2020;3: pubmed publisher
Meng K, Majedi F, Thauland T, Butte M. Mechanosensing through YAP controls T cell activation and metabolism. J Exp Med. 2020;217: pubmed publisher
Pflügler S, Svinka J, Scharf I, Crncec I, Filipits M, Charoentong P, et al. IDO1+ Paneth cells promote immune escape of colorectal cancer. Commun Biol. 2020;3:252 pubmed publisher
Runge E, Iyer A, Setter D, Kennedy F, Sanders V, Jones K. CD4+ T cell expression of the IL-10 receptor is necessary for facial motoneuron survival after axotomy. J Neuroinflammation. 2020;17:121 pubmed publisher
Lu Y, Zhao Q, Liao J, Song E, Xia Q, Pan J, et al. Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity. Cell. 2020;180:1081-1097.e24 pubmed publisher
Luck H, Khan S, Kim J, Copeland J, Revelo X, Tsai S, et al. Gut-associated IgA+ immune cells regulate obesity-related insulin resistance. Nat Commun. 2019;10:3650 pubmed publisher
Li X, Li D, Shi Q, Huang X, Ju X. Umbilical cord blood‑derived Helios‑positive regulatory T cells promote angiogenesis in acute lymphoblastic leukemia in mice via CCL22 and the VEGFA‑VEGFR2 pathway. Mol Med Rep. 2019;19:4195-4204 pubmed publisher
Becher J, Simula L, Volpe E, Procaccini C, La Rocca C, D Acunzo P, et al. AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis. Dev Cell. 2018;47:592-607.e6 pubmed publisher
Lin J, Izar B, Wang S, Yapp C, Mei S, Shah P, et al. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. elife. 2018;7: pubmed publisher
Su M, Hu R, Song Y, Liu Y, Lai L. Targeted deletion of c-Met in thymic epithelial cells leads to an autoimmune phenotype. Immunol Cell Biol. 2018;96:229-235 pubmed publisher
Chmielewski M, Abken H. CAR T Cells Releasing IL-18 Convert to T-Bethigh FoxO1low Effectors that Exhibit Augmented Activity against Advanced Solid Tumors. Cell Rep. 2017;21:3205-3219 pubmed publisher
Zhu D, Tan J, Maleken A, Muljadi R, Chan S, Lau S, et al. Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury. Stem Cell Res Ther. 2017;8:257 pubmed publisher
Perkins T, Rosenberg J, Le Coz C, Alaimo J, Trofa M, Mullegama S, et al. Smith-Magenis Syndrome Patients Often Display Antibody Deficiency but Not Other Immune Pathologies. J Allergy Clin Immunol Pract. 2017;5:1344-1350.e3 pubmed publisher
Dotsey E, Ushach I, Pone E, Nakajima R, Jasinskas A, Argueta D, et al. Transient Cannabinoid Receptor 2 Blockade during Immunization Heightens Intensity and Breadth of Antigen-specific Antibody Responses in Young and Aged mice. Sci Rep. 2017;7:42584 pubmed publisher
Groen B, van der Wijk A, van den Berg P, Lefrandt J, van den Berg G, Sollie K, et al. Immunological Adaptations to Pregnancy in Women with Type 1 Diabetes. Sci Rep. 2015;5:13618 pubmed publisher
Prado Garcia H, Romero Garcia S, Rumbo Nava U, Lopez Gonzalez J. Predominance of Th17 over regulatory T-cells in pleural effusions of patients with lung cancer implicates a proinflammatory profile. Anticancer Res. 2015;35:1529-35 pubmed
Xie L, Sun F, Wang J, Mao X, Xie L, Yang S, et al. mTOR signaling inhibition modulates macrophage/microglia-mediated neuroinflammation and secondary injury via regulatory T cells after focal ischemia. J Immunol. 2014;192:6009-19 pubmed publisher
Murakami R, Denda Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T. A unique dermal dendritic cell subset that skews the immune response toward Th2. PLoS ONE. 2013;8:e73270 pubmed publisher
Liu Y, Lan Q, Lu L, Chen M, Xia Z, Ma J, et al. Phenotypic and functional characteristic of a newly identified CD8+ Foxp3- CD103+ regulatory T cells. J Mol Cell Biol. 2014;6:81-92 pubmed publisher
Xiong Y, Khanna S, Grzenda A, Sarmento O, Svingen P, Lomberk G, et al. Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner. J Biol Chem. 2012;287:34372-85 pubmed publisher
Zhu P, Hata R, Ogasawara M, Cao F, Kameda K, Yamauchi K, et al. Targeted disruption of organic cation transporter 3 (Oct3) ameliorates ischemic brain damage through modulating histamine and regulatory T cells. J Cereb Blood Flow Metab. 2012;32:1897-908 pubmed publisher
Oida T, Weiner H. TGF-? induces surface LAP expression on murine CD4 T cells independent of Foxp3 induction. PLoS ONE. 2010;5:e15523 pubmed publisher
Haque A, Stanley A, Amante F, Rivera F, Zhou Y, Kuns R, et al. Therapeutic glucocorticoid-induced TNF receptor-mediated amplification of CD4+ T cell responses enhances antiparasitic immunity. J Immunol. 2010;184:2583-92 pubmed publisher
Klunker S, Chong M, Mantel P, Palomares O, Bassin C, Ziegler M, et al. Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells. J Exp Med. 2009;206:2701-15 pubmed publisher
Fallarino F, Luca G, Calvitti M, Mancuso F, Nastruzzi C, Fioretti M, et al. Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone. J Exp Med. 2009;206:2511-26 pubmed publisher
Golovina T, Mikheeva T, Suhoski M, Aqui N, Tai V, Shan X, et al. CD28 costimulation is essential for human T regulatory expansion and function. J Immunol. 2008;181:2855-68 pubmed
Jordan J, Woods M, Olano J, Walker D. The absence of Toll-like receptor 4 signaling in C3H/HeJ mice predisposes them to overwhelming rickettsial infection and decreased protective Th1 responses. Infect Immun. 2008;76:3717-24 pubmed publisher
Valencia X, Yarboro C, Illei G, Lipsky P. Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus. J Immunol. 2007;178:2579-88 pubmed
Mayack S, Berg L. Cutting edge: an alternative pathway of CD4+ T cell differentiation is induced following activation in the absence of gamma-chain-dependent cytokine signals. J Immunol. 2006;176:2059-63 pubmed
product information
Antigen :
FOXP3
Apps. Abbrev. :
ICFC
Cat # :
320012
Clone :
150D
Item :
Alexa Fluor® 488 anti-mouse/rat/human FOXP3
Isotype :
Mouse IgG1, κ
Other Names :
Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2
Size :
100 tests
Price (USD) :
370 USD
Reactivity :
Human, Mouse, Rat
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
A488
Immunogen :
Full-length FOXP3 protein
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA