PerCP anti-human CD4 | BioLegend 317431 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PerCP anti-human CD4

catalog :

317431

quantity :

25 tests

price :

153 USD

clonality :

monoclonal

host :

mouse

conjugate :

PerCP

clone name :

OKT4

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 7a	Saxena V, Piao W, Li L, Paluskievicz C, Xiong Y, Simon T, et al. Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses. Cell Rep. 2022;39:110727 pubmed publisher
flow cytometry; human; loading ...; fig 1	Ondigo B, Ndombi E, Nicholson S, Oguso J, Carter J, Kittur N, et al. Functional Studies of T Regulatory Lymphocytes in Human Schistosomiasis in Western Kenya. Am J Trop Med Hyg. 2018;98:1770-1781 pubmed publisher
flow cytometry; human; 1:25; loading ...; fig 2a	Siegers G, Barreira C, Postovit L, Dekaban G. CD11d ?2 integrin expression on human NK, B, and ?? T cells. J Leukoc Biol. 2017;101:1029-1035 pubmed publisher
	Wilson A, Randall K, Pettitt J, Ellyard J, Blumenthal A, Enders A, et al. Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2. Nat Commun. 2022;13:528 pubmed publisher
	Zhang H, Sun M, Wang J, Zeng B, Cao X, Han Y, et al. Identification of NY-ESO-1157-165 Specific Murine T Cell Receptors With Distinct Recognition Pattern for Tumor Immunotherapy. Front Immunol. 2021;12:644520 pubmed publisher
	Tao L, Farooq M, Gao Y, Zhang L, Niu C, Ajmal I, et al. CD19-CAR-T Cells Bearing a KIR/PD-1-Based Inhibitory CAR Eradicate CD19+HLA-C1- Malignant B Cells While Sparing CD19+HLA-C1+ Healthy B Cells. Cancers (Basel). 2020;12: pubmed publisher
	Vyas A, Negi P, Patra S, Maras J, Ramakrishna G, Sarin S, et al. Maternal Immunity Influences Vertical Transmission of Hepatitis B to Newborns. Hepatol Commun. 2019;3:795-811 pubmed publisher
	Zhai Y, Lin P, Feng Z, Lu H, Han Q, Chen J, et al. TNFAIP3-DEPTOR complex regulates inflammasome secretion through autophagy in ankylosing spondylitis monocytes. Autophagy. 2018;14:1629-1643 pubmed publisher
	Shan L, Deng K, Gao H, Xing S, Capoferri A, Durand C, et al. Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4+ T Cells Permissive for Latent HIV-1 Infection. Immunity. 2017;47:766-775.e3 pubmed publisher
	Ishizaka A, Sato H, Nakamura H, Koga M, Kikuchi T, Hosoya N, et al. Short Intracellular HIV-1 Transcripts as Biomarkers of Residual Immune Activation in Patients on Antiretroviral Therapy. J Virol. 2016;90:5665-5676 pubmed publisher
	Bartholomaeus P, Semmler L, Bukur T, Boisguerin V, Römer P, Tabares P, et al. Cell contact-dependent priming and Fc interaction with CD32+ immune cells contribute to the TGN1412-triggered cytokine response. J Immunol. 2014;192:2091-8 pubmed publisher
	Liu X, Gao N, Li M, Xu D, Hou Y, Wang Q, et al. Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction. PLoS ONE. 2013;8:e64531 pubmed publisher
	Cicin Sain L, Smyk Pearson S, Smyk Paerson S, Currier N, Byrd L, Koudelka C, et al. Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates. J Immunol. 2010;184:6739-45 pubmed publisher
	Kmieciak M, Gowda M, Graham L, Godder K, Bear H, Marincola F, et al. Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function. J Transl Med. 2009;7:89 pubmed publisher

product information

Antigen :

CD4

Apps. Abbrev. :

Cat # :

317431

Clone :

OKT4

Item :

PerCP anti-human CD4

Isotype :

Mouse IgG2b, κ

Other Names :

Size :

25 tests

Price (USD) :

153 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PERCP

Immunogen :

Human peripheral T cells

Application Notes :

The OKT4 antibody binds to the D3 domain of CD4 and does not block HIV binding. Additional reported applications (for the relevant formats) include: immunohistochemistry of frozen sections and blocking of T cell activation. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 317453 and 317454).In a small subset of individuals, the OKT4 clone does not bind to CD4 due to polymorphisms in CD4.^9;

more info or order :

BioLegend product webpage