PE/Cyanine5 anti-human CD4 | BioLegend 317411 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Cyanine5 anti-human CD4

catalog :

317411

quantity :

25 tests

price :

124 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OKT4

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 6

Reference
Maleki K, Tauriainen J, García M, Kerkman P, Christ W, Dias J, et al. MAIT cell activation is associated with disease severity markers in acute hantavirus infection. Cell Rep Med. 2021;2:100220 pubmed publisher
Pattekar A, Mayer L, Lau C, Liu C, Palko O, Bewtra M, et al. Norovirus-Specific CD8+ T Cell Responses in Human Blood and Tissues. Cell Mol Gastroenterol Hepatol. 2021;11:1267-1289 pubmed publisher
Freeman Z, Nirschl T, Hovelson D, Johnston R, Engelhardt J, Selby M, et al. A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target. J Clin Invest. 2020;130:1405-1416 pubmed publisher
Ivarsson M, Stiglund N, Marquardt N, Westgren M, Gidlöf S, Björkström N. Composition and dynamics of the uterine NK cell KIR repertoire in menstrual blood. Mucosal Immunol. 2017;10:322-331 pubmed publisher
Yang B, Zhai F, Jiang J, Wang X, Cao Z, Cheng X. Elevated expression of T-bet in mycobacterial antigen-specific CD4(+) T cells from patients with tuberculosis. Cell Immunol. 2015;298:1-8 pubmed publisher
Blom L, Poulsen B, Jensen B, Hansen A, Poulsen L. IL-33 induces IL-9 production in human CD4+ T cells and basophils. PLoS ONE. 2011;6:e21695 pubmed publisher

product information

Antigen :

CD4

Apps. Abbrev. :

Cat # :

317411

Clone :

OKT4

Item :

PE/Cyanine5 anti-human CD4

Isotype :

Mouse IgG2b, κ

Other Names :

Size :

25 tests

Price (USD) :

124 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PE_CYANINE5

Immunogen :

Human peripheral T cells

Application Notes :

The OKT4 antibody binds to the D3 domain of CD4 and does not block HIV binding. Additional reported applications (for the relevant formats) include: immunohistochemistry of frozen sections and blocking of T cell activation. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 317453 and 317454).In a small subset of individuals, the OKT4 clone does not bind to CD4 due to polymorphisms in CD4.^9;

more info or order :

BioLegend product webpage