Biotin anti-human CD4 | BioLegend 317405 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Biotin anti-human CD4

catalog :

317405

quantity :

25 μg

price :

33 USD

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

OKT4

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 4

Reference
Delacher M, Simon M, Sanderink L, Hotz Wagenblatt A, Wuttke M, Schambeck K, et al. Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells. Immunity. 2021;54:702-720.e17 pubmed publisher
Hirota K, Hashimoto M, Ito Y, Matsuura M, Ito H, Tanaka M, et al. Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis. Immunity. 2018;48:1220-1232.e5 pubmed publisher
Kanakasabapathy M, Pandya H, Draz M, Chug M, Sadasivam M, Kumar S, et al. Rapid, label-free CD4 testing using a smartphone compatible device. Lab Chip. 2017;17:2910-2919 pubmed publisher
Liu M, Yang G, Wiehe K, Nicely N, Vandergrift N, Rountree W, et al. Polyreactivity and autoreactivity among HIV-1 antibodies. J Virol. 2015;89:784-98 pubmed publisher

product information

Antigen :

CD4

Apps. Abbrev. :

Cat # :

317405

Clone :

OKT4

Item :

Biotin anti-human CD4

Isotype :

Mouse IgG2b, κ

Other Names :

Size :

25 μg

Price (USD) :

33 USD

Reactivity :

Human, Cynomolgus, Rhesus

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

BIOTIN

Immunogen :

Human peripheral T cells

Application Notes :

The OKT4 antibody binds to the D3 domain of CD4 and does not block HIV binding. Additional reported applications (for the relevant formats) include: immunohistochemistry of frozen sections and blocking of T cell activation. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 317453 and 317454).In a small subset of individuals, the OKT4 clone does not bind to CD4 due to polymorphisms in CD4.^9;

more info or order :

BioLegend product webpage