Brilliant Violet 421™ anti-human CD3 | BioLegend 317344 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 421™ anti-human CD3

catalog :

317344

quantity :

100 tests

price :

360 USD

clonality :

monoclonal

host :

mouse

conjugate :

BV421

clone name :

OKT3

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 8

Reference
Qiu J, Nordling S, Vasavada H, Butcher E, Hirschi K. Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification. Cell Rep. 2020;33:108465 pubmed publisher
Vera Aguilera J, Paludo J, McWilliams R, Zhang H, Li Y, Kumar A, et al. Chemo-immunotherapy combination after PD-1 inhibitor failure improves clinical outcomes in metastatic melanoma patients. Melanoma Res. 2020;30:364-375 pubmed publisher
Di Genua C, Valletta S, Buono M, Stoilova B, Sweeney C, Rodriguez Meira A, et al. C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor. Cancer Cell. 2020;37:690-704.e8 pubmed publisher
PLUM T, Wang X, Rettel M, Krijgsveld J, Feyerabend T, Rodewald H. Human Mast Cell Proteome Reveals Unique Lineage, Putative Functions, and Structural Basis for Cell Ablation. Immunity. 2020;52:404-416.e5 pubmed publisher
Willcox C, Vantourout P, Salim M, Zlatareva I, Melandri D, Zanardo L, et al. Butyrophilin-like 3 Directly Binds a Human Vγ4+ T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen. Immunity. 2019;51:813-825.e4 pubmed publisher
Yan Y, Cao S, Liu X, Harrington S, Bindeman W, Adjei A, et al. CX3CR1 identifies PD-1 therapy-responsive CD8+ T cells that withstand chemotherapy during cancer chemoimmunotherapy. JCI Insight. 2018;3: pubmed publisher
Telford W, Stickland L, Koschorreck M. Ultraviolet 320 nm laser excitation for flow cytometry. Cytometry A. 2017;91:314-325 pubmed publisher
Walker Sperling V, Pohlmeyer C, Veenhuis R, May M, Luna K, Kirkpatrick A, et al. Factors Associated With the Control of Viral Replication and Virologic Breakthrough in a Recently Infected HIV-1 Controller. EBioMedicine. 2017;16:141-149 pubmed publisher

product information

Antigen :

CD3

Apps. Abbrev. :

Cat # :

317344

Clone :

OKT3

Item :

Brilliant Violet 421™ anti-human CD3

Isotype :

Mouse IgG2a, κ

Other Names :

T3, CD3ε

Size :

100 tests

Price (USD) :

360 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

BV421

Application Notes :

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex.Clone OKT3 can block the binding of clones SK7 and UCHT1.^4 The OKT3 antibody is able to induce T cell activation. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections and activation of T cells. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 317304). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 317326) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage