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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-human CD3
catalog :
317344
quantity :
100 tests
price :
360 USD
clonality :
monoclonal
host :
mouse
conjugate :
BV421
clone name :
OKT3
reactivity :
human
application :
flow cytometry
more info or order :
citations: 20
Reference
Lah S, Kim S, Kang I, Kim H, Hupperetz C, Jung H, et al. Engineering second-generation TCR-T cells by site-specific integration of TRAF-binding motifs into the CD247 locus. J Immunother Cancer. 2023;11: pubmed publisher
Lellahi S, Azeem W, Hua Y, Gabriel B, Paulsen Rye K, Reikvam H, et al. GM-CSF, Flt3-L and IL-4 affect viability and function of conventional dendritic cell types 1 and 2. Front Immunol. 2022;13:1058963 pubmed publisher
Hong C, Pyo H, Baek I, Kim T. Rapid identification of CMV-specific TCRs via reverse TCR cloning system based on bulk TCR repertoire data. Front Immunol. 2022;13:1021067 pubmed publisher
Cox M, Manriquez Roman C, Tapper E, Siegler E, Chappell D, Durrant C, et al. GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity. Leukemia. 2022;36:1635-1645 pubmed publisher
Schloss M, Hulsmans M, Rohde D, Lee I, Severe N, Foy B, et al. B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis. Nat Immunol. 2022;23:605-618 pubmed publisher
Qi S, Ngwa C, Morales Scheihing D, Al Mamun A, Ahnstedt H, Finger C, et al. Sex differences in the immune response to acute COVID-19 respiratory tract infection. Biol Sex Differ. 2021;12:66 pubmed publisher
Gamradt S, Hasselmann H, Taenzer A, Brasanac J, Stiglbauer V, Sattler A, et al. Reduced mitochondrial respiration in T cells of patients with major depressive disorder. iScience. 2021;24:103312 pubmed publisher
Nian Z, Zheng X, Dou Y, Du X, Zhou L, Fu B, et al. Rapamycin Pretreatment Rescues the Bone Marrow AML Cell Elimination Capacity of CAR-T Cells. Clin Cancer Res. 2021;27:6026-6038 pubmed publisher
Hirschberger S, Strauß G, Effinger D, Marstaller X, Ferstl A, Müller M, et al. Very-low-carbohydrate diet enhances human T-cell immunity through immunometabolic reprogramming. EMBO Mol Med. 2021;13:e14323 pubmed publisher
Zong D, Huang B, LI Y, Lu Y, Xiang N, Guo C, et al. Chromatin accessibility landscapes of immune cells in rheumatoid arthritis nominate monocytes in disease pathogenesis. BMC Biol. 2021;19:79 pubmed publisher
Wang L, Verschuuren E, Paap D, Rondaan C, Raveling Eelsing E, Liu S, et al. Ageing of Immune System and Response to a Live-Attenuated Herpes Zoster Vaccine in Lung Transplant Candidates. Vaccines (Basel). 2021;9: pubmed publisher
Qiu J, Nordling S, Vasavada H, Butcher E, Hirschi K. Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification. Cell Rep. 2020;33:108465 pubmed publisher
Port J, Wozniak D, Oestereich L, Pallasch E, Becker Ziaja B, M xfc ller J, et al. Severe Human Lassa Fever Is Characterized by Nonspecific T-Cell Activation and Lymphocyte Homing to Inflamed Tissues. J Virol. 2020;94: pubmed publisher
Vera Aguilera J, Paludo J, McWilliams R, Zhang H, Li Y, Kumar A, et al. Chemo-immunotherapy combination after PD-1 inhibitor failure improves clinical outcomes in metastatic melanoma patients. Melanoma Res. 2020;30:364-375 pubmed publisher
Di Genua C, Valletta S, Buono M, Stoilova B, Sweeney C, Rodriguez Meira A, et al. C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor. Cancer Cell. 2020;37:690-704.e8 pubmed publisher
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Willcox C, Vantourout P, Salim M, Zlatareva I, Melandri D, Zanardo L, et al. Butyrophilin-like 3 Directly Binds a Human Vγ4+ T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen. Immunity. 2019;51:813-825.e4 pubmed publisher
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product information
Antigen :
CD3
Apps. Abbrev. :
FC
Cat # :
317344
Clone :
OKT3
Item :
Brilliant Violet 421™ anti-human CD3
Isotype :
Mouse IgG2a, κ
Other Names :
T3, CD3ε
Size :
100 tests
Price (USD) :
360 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BV421
Application Notes :
The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex.Clone OKT3 can block the binding of clones SK7 and UCHT1.^4 The OKT3 antibody is able to induce T cell activation. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections and activation of T cells. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 317304). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 317326) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA