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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PerCP/Cyanine5.5 anti-human CD3
catalog :
317336
quantity :
100 tests
price :
229 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OKT3
reactivity :
human
application :
flow cytometry
more info or order :
citations: 28
Reference
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Fernandez R, Mayoral J, Pierre Louis L, Yao Y, Xu Y, Mu S, et al. Improving NK cell function in multiple myeloma with NKTR-255, a novel polymer-conjugated human IL-15. Blood Adv. 2023;7:9-19 pubmed publisher
Khuisangeam N, Jewmoung S, Thaiwong R, Tudsamran S, Hirankarn N, Suppipat K, et al. An In Vitro Comparison of Costimulatory Domains in Chimeric Antigen Receptor T Cell for Breast Cancer Treatment. J Immunol Res. 2022;2022:2449373 pubmed publisher
Barnes C, Schoofs T, Gnanapragasam P, Golijanin J, Huey Tubman K, Gruell H, et al. A naturally arising broad and potent CD4-binding site antibody with low somatic mutation. Sci Adv. 2022;8:eabp8155 pubmed publisher
Aschmoneit N, Kocher K, Siegemund M, Lutz M, Kühl L, Seifert O, et al. Fc-based Duokines: dual-acting costimulatory molecules comprising TNFSF ligands in the single-chain format fused to a heterodimerizing Fc (scDk-Fc). Oncoimmunology. 2022;11:2028961 pubmed publisher
Hakki S, Robinson E, Robson M. Circulating Interleukin-6 and CD16 positive monocytes increase following angioplasty of an arteriovenous fistula. Sci Rep. 2022;12:1427 pubmed publisher
Mudd P, Minervina A, Pogorelyy M, Turner J, Kim W, Kalaidina E, et al. SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans. Cell. 2022;185:603-613.e15 pubmed publisher
Kasper M, Heming M, Schafflick D, Li X, Lautwein T, Meyer Zu Hörste M, et al. Intraocular dendritic cells characterize HLA-B27-associated acute anterior uveitis. elife. 2021;10: pubmed publisher
Aschmoneit N, K xfc hl L, Seifert O, Kontermann R. Fc-comprising scDb-based trivalent, bispecific T-cell engagers for selective killing of HER3-expressing cancer cells independent of cytokine release. J Immunother Cancer. 2021;9: pubmed publisher
Bulgarelli J, Piccinini C, Petracci E, Pancisi E, Granato A, De Rosa F, et al. Radiotherapy and High-Dose Interleukin-2: Clinical and Immunological Results of a Proof of Principle Study in Metastatic Melanoma and Renal Cell Carcinoma. Front Immunol. 2021;12:778459 pubmed publisher
Billing F, Walter B, Fink S, Arefaine E, Pickarski L, Maier S, et al. Altered Proinflammatory Responses to Polyelectrolyte Multilayer Coatings Are Associated with Differences in Protein Adsorption and Wettability. ACS Appl Mater Interfaces. 2021;13:55534-55549 pubmed publisher
Wu X, Sharma A, Oldenburg J, Weiher H, Essler M, Skowasch D, et al. NKG2D Engagement Alone Is Sufficient to Activate Cytokine-Induced Killer Cells While 2B4 Only Provides Limited Coactivation. Front Immunol. 2021;12:731767 pubmed publisher
Eiva M, Omran D, Chacon J, Powell D. Systematic analysis of CD39, CD103, CD137, and PD-1 as biomarkers for naturally occurring tumor antigen-specific TILs. Eur J Immunol. 2022;52:96-108 pubmed publisher
Wu J, Chen Z, Wickström S, Gao J, He X, Jing X, et al. Interleukin-33 is a Novel Immunosuppressor that Protects Cancer Cells from TIL Killing by a Macrophage-Mediated Shedding Mechanism. Adv Sci (Weinh). 2021;8:e2101029 pubmed publisher
Zhang Z, Liu Q, Tan J, Zhan X, Liu T, Wang Y, et al. Coating with flexible DNA network enhanced T-cell activation and tumor killing for adoptive cell therapy. Acta Pharm Sin B. 2021;11:1965-1977 pubmed publisher
Lee E, Szvetecz S, Polli R, Grauel A, Chen J, Judge J, et al. PAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer. Sci Rep. 2021;11:14841 pubmed publisher
Tian X, Cui Z, Wang S, Pan Y, Lata A, Chen X, et al. Low serum IgG4 level: a potential diagnostic biomarker for IgA nephropathy. Ann Transl Med. 2021;9:781 pubmed publisher
Aschmoneit N, Steinlein S, Kühl L, Seifert O, Kontermann R. A scDb-based trivalent bispecific antibody for T-cell-mediated killing of HER3-expressing cancer cells. Sci Rep. 2021;11:13880 pubmed publisher
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Riquelme S, Liimatta K, Wong Fok Lung T, Fields B, Ahn D, Chen D, et al. Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation. Cell Metab. 2020;31:1091-1106.e6 pubmed publisher
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product information
Antigen :
CD3
Apps. Abbrev. :
FC
Cat # :
317336
Clone :
OKT3
Item :
PerCP/Cyanine5.5 anti-human CD3
Isotype :
Mouse IgG2a, κ
Other Names :
T3, CD3ε
Size :
100 tests
Price (USD) :
229 USD
Reactivity :
Human
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PERCP_CYANINE5.5
Application Notes :
The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex.Clone OKT3 can block the binding of clones SK7 and UCHT1.^4 The OKT3 antibody is able to induce T cell activation. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections and activation of T cells. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 317304). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 317326) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA