APC anti-human CD3 | BioLegend 317318 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-human CD3

catalog :

317318

quantity :

100 tests

price :

77 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

OKT3

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:1000; loading ...	Zhang T, Xia W, Song X, Mao Q, Huang X, Chen B, et al. Super-enhancer hijacking LINC01977 promotes malignancy of early-stage lung adenocarcinoma addicted to the canonical TGF-β/SMAD3 pathway. J Hematol Oncol. 2022;15:114 pubmed publisher
	Bäcker Koduah P, Infante Duarte C, Ivaldi F, Uccelli A, Bellmann Strobl J, Wernecke K, et al. Effect of vitamin D supplementation on N-glycan branching and cellular immunophenotypes in MS. Ann Clin Transl Neurol. 2020;: pubmed publisher
	Li Z, Deng M, Huang F, Jin C, Sun S, Chen H, et al. LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells. Cell Mol Immunol. 2020;17:272-282 pubmed publisher
	Selich A, Ha T, Morgan M, Falk C, von Kaisenberg C, Schambach A, et al. Cytokine Selection of MSC Clones with Different Functionality. Stem Cell Reports. 2019;13:262-273 pubmed publisher
	Chen J, Chernatynskaya A, Li J, Kimbrell M, Cassidy R, Perry D, et al. T cells display mitochondria hyperpolarization in human type 1 diabetes. Sci Rep. 2017;7:10835 pubmed publisher
	Siedlik J, Deckert J, Benedict S, Bhatta A, Dunbar A, Vardiman J, et al. T cell activation and proliferation following acute exercise in human subjects is altered by storage conditions and mitogen selection. J Immunol Methods. 2017;446:7-14 pubmed publisher
	Fisher J, Abramowski P, Wisidagamage Don N, Flutter B, Capsomidis A, Cheung G, et al. Avoidance of On-Target Off-Tumor Activation Using a Co-stimulation-Only Chimeric Antigen Receptor. Mol Ther. 2017;25:1234-1247 pubmed publisher
	Sharei A, Trifonova R, Jhunjhunwala S, Hartoularos G, Eyerman A, Lytton Jean A, et al. Ex vivo cytosolic delivery of functional macromolecules to immune cells. PLoS ONE. 2015;10:e0118803 pubmed publisher

product information

Antigen :

CD3

Apps. Abbrev. :

Cat # :

317318

Clone :

OKT3

Item :

APC anti-human CD3

Isotype :

Mouse IgG2a, κ

Other Names :

T3, CD3ε

Size :

100 tests

Price (USD) :

77 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

APC

Application Notes :

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex.Clone OKT3 can block the binding of clones SK7 and UCHT1.^4 The OKT3 antibody is able to induce T cell activation. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections and activation of T cells. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 317304). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 317326) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage