Pacific Blue™ anti-human CD3 | BioLegend 317314 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Pacific Blue™ anti-human CD3

catalog :

317314

quantity :

100 μg

price :

265 USD

clonality :

monoclonal

host :

mouse

conjugate :

Pacific Blue

clone name :

OKT3

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 6

Reference
Bernardes J, Mishra N, Tran F, Bahmer T, Best L, Blase J, et al. Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19. Immunity. 2020;53:1296-1314.e9 pubmed publisher
Daniels J, Doukas P, Escala M, Ringbloom K, Shih D, Yang J, et al. Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas. Nat Commun. 2020;11:1806 pubmed publisher
Zaikos T, Terry V, Sebastian Kettinger N, Lubow J, Painter M, Virgilio M, et al. Hematopoietic Stem and Progenitor Cells Are a Distinct HIV Reservoir that Contributes to Persistent Viremia in Suppressed Patients. Cell Rep. 2018;25:3759-3773.e9 pubmed publisher
Guo X, Dash P, CALVERLEY M, Tomchuck S, Dallas M, Thomas P. Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis. Mol Ther Methods Clin Dev. 2016;3:15054 pubmed publisher
Collins D, Lubow J, Lukic Z, Mashiba M, Collins K. Vpr Promotes Macrophage-Dependent HIV-1 Infection of CD4+ T Lymphocytes. PLoS Pathog. 2015;11:e1005054 pubmed publisher
Hope C, Grace B, Pilkington K, Coates P, Bergmann I, Carroll R. The immune phenotype may relate to cancer development in kidney transplant recipients. Kidney Int. 2014;86:175-83 pubmed publisher

product information

Antigen :

CD3

Apps. Abbrev. :

Cat # :

317314

Clone :

OKT3

Item :

Pacific Blue™ anti-human CD3

Isotype :

Mouse IgG2a, κ

Other Names :

T3, CD3ε

Size :

100 μg

Price (USD) :

265 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Application Notes :

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex.Clone OKT3 can block the binding of clones SK7 and UCHT1.^4 The OKT3 antibody is able to induce T cell activation. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections and activation of T cells. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 317304). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 317326) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage