Pacific Blue™ anti-human CD3 | BioLegend 317314 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Pacific Blue™ anti-human CD3

catalog :

317314

quantity :

100 μg

price :

265 USD

clonality :

monoclonal

host :

mouse

conjugate :

Pacific Blue

clone name :

OKT3

reactivity :

human

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 14

Reference
Beck C, Casey N, Persiconi I, Moharrami N, Sike A, Jin Y, et al. Development of a TGFβ-IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy. Biomedicines. 2023;11: pubmed publisher
Lao L, Zeng W, Huang P, Chen H, Jia Z, Wang P, et al. CD8+ T cell-Dependent Remodeling of the Tumor Microenvironment Overcomes Chemoresistance. Cancer Immunol Res. 2023;11:320-338 pubmed publisher
C xf4 rte Real B, Arroyo Hornero R, Dyczko A, Hamad I, Kleinewietfeld M. Dissecting the role of CSF2RB expression in human regulatory T cells. Front Immunol. 2022;13:1005965 pubmed publisher
LaSalle T, Gonye A, Freeman S, Kaplonek P, Gushterova I, Kays K, et al. Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patients. Cell Rep Med. 2022;3:100779 pubmed publisher
Xia Q, Huang H, Davis M. A High-Throughput Strategy for T-Cell Receptor Cloning and Expression. Methods Mol Biol. 2022;2574:251-264 pubmed publisher
Welbourn S, Chakraborty S, Yang J, Gleinich A, Gangadhara S, Khan S, et al. A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence. PLoS Pathog. 2022;18:e1010488 pubmed publisher
Qian Y, Arellano G, Ifergan I, Lin J, Snowden C, Kim T, et al. ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis. Cell Rep. 2021;36:109602 pubmed publisher
Charles T, Burton S, Arunachalam P, Cottrell C, Sewall L, Bollimpelli V, et al. The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection. PLoS Pathog. 2021;17:e1009257 pubmed publisher
Bernardes J, Mishra N, Tran F, Bahmer T, Best L, Blase J, et al. Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19. Immunity. 2020;53:1296-1314.e9 pubmed publisher
Daniels J, Doukas P, Escala M, Ringbloom K, Shih D, Yang J, et al. Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas. Nat Commun. 2020;11:1806 pubmed publisher
Zaikos T, Terry V, Sebastian Kettinger N, Lubow J, Painter M, Virgilio M, et al. Hematopoietic Stem and Progenitor Cells Are a Distinct HIV Reservoir that Contributes to Persistent Viremia in Suppressed Patients. Cell Rep. 2018;25:3759-3773.e9 pubmed publisher
Guo X, Dash P, CALVERLEY M, Tomchuck S, Dallas M, Thomas P. Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis. Mol Ther Methods Clin Dev. 2016;3:15054 pubmed publisher
Collins D, Lubow J, Lukic Z, Mashiba M, Collins K. Vpr Promotes Macrophage-Dependent HIV-1 Infection of CD4+ T Lymphocytes. PLoS Pathog. 2015;11:e1005054 pubmed publisher
Hope C, Grace B, Pilkington K, Coates P, Bergmann I, Carroll R. The immune phenotype may relate to cancer development in kidney transplant recipients. Kidney Int. 2014;86:175-83 pubmed publisher

product information

Antigen :

CD3

Apps. Abbrev. :

Cat # :

317314

Clone :

OKT3

Item :

Pacific Blue™ anti-human CD3

Isotype :

Mouse IgG2a, κ

Other Names :

T3, CD3ε

Size :

100 μg

Price (USD) :

265 USD

Reactivity :

Human

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

Application Notes :

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex.Clone OKT3 can block the binding of clones SK7 and UCHT1.^4 The OKT3 antibody is able to induce T cell activation. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections and activation of T cells. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 317304). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 317326) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage